$115 Cheap Flights from Chicago (MDW) to Panama City (ECP)

View $115 flight on Sun, Dec 14, 2025Opens in a new window

Popular airlines from Chicago Midway Airport (MDW) to Northwest Florida Beaches Intl. Airport (ECP)

Cheap Flights from Chicago to Panama City (MDW-ECP)

Prices were available within the past 7 days and start at $115 for one-way flights and $166 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Wed, Jan 7 - Thu, Jan 8
MDW
Chicago
ECP
Panama City
$166 Roundtrip, found 5 days ago
$166
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Wed, Jan 7 from Chicago to Panama City, returning Thu, Jan 8, priced at $166 found 5 days ago
Southwest Airlines
Thu, Jan 8 - Mon, Jan 12
MDW
Chicago
ECP
Panama City
$175 Roundtrip, found 6 days ago
$175
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Thu, Jan 8 from Chicago to Panama City, returning Mon, Jan 12, priced at $175 found 6 days ago
Delta
Thu, Dec 11 - Sat, Dec 13
MDW
Chicago
ECP
Panama City
$179 Roundtrip, found 5 days ago
$179
Roundtrip
found 5 days ago
Select Delta flight, departing Thu, Dec 11 from Chicago to Panama City, returning Sat, Dec 13, priced at $179 found 5 days ago
Delta
Wed, Jan 7 - Thu, Jan 8
MDW
Chicago
ECP
Panama City
$186 Roundtrip, found 5 days ago
$186
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Jan 7 from Chicago to Panama City, returning Thu, Jan 8, priced at $186 found 5 days ago
Southwest Airlines
Thu, Dec 11 - Sat, Dec 13
MDW
Chicago
ECP
Panama City
$187 Roundtrip, found 5 days ago
$187
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Thu, Dec 11 from Chicago to Panama City, returning Sat, Dec 13, priced at $187 found 5 days ago
Delta
Fri, Jan 9 - Mon, Jan 12
MDW
Chicago
ECP
Panama City
$193 Roundtrip, found 6 days ago
$193
Roundtrip
found 6 days ago
Select Delta flight, departing Fri, Jan 9 from Chicago to Panama City, returning Mon, Jan 12, priced at $193 found 6 days ago
Southwest Airlines
Tue, Feb 17 - Tue, Feb 24
MDW
Chicago
ECP
Panama City
$195 Roundtrip, found 5 days ago
$195
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Tue, Feb 17 from Chicago to Panama City, returning Tue, Feb 24, priced at $195 found 5 days ago
Southwest Airlines
Thu, Feb 5 - Mon, Feb 9
MDW
Chicago
ECP
Panama City
$196 Roundtrip, found 6 days ago
$196
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Thu, Feb 5 from Chicago to Panama City, returning Mon, Feb 9, priced at $196 found 6 days ago
Southwest Airlines
Mon, Jan 5 - Tue, Jan 6
MDW
Chicago
ECP
Panama City
$198 Roundtrip, found 5 days ago
$198
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Mon, Jan 5 from Chicago to Panama City, returning Tue, Jan 6, priced at $198 found 5 days ago
Southwest Airlines
Tue, Jan 6 - Wed, Jan 7
MDW
Chicago
ECP
Panama City
$198 Roundtrip, found 5 days ago
$198
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Tue, Jan 6 from Chicago to Panama City, returning Wed, Jan 7, priced at $198 found 5 days ago

Find the cheapest month to fly from Chicago (MDW) to Panama City (ECP)

August is typically the cheapest month to fly

From $176 - $607 per traveler.

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Northwest Florida Beaches Intl. ECP. Cheapest and Closest option available. Average driving time to city center is 35 minutes. Flights from $269
ECP
Northwest Florida Beaches Intl.
CheapestClosest
Average driving time to city center35 min
Flights from $269
Flights from Chicago (MDW) to Panama City (ECP)
Origin airport
Midway Intl.
Destination airport
Northwest Florida Beaches Intl.
Airlines serving
Delta, Southwest Airlines
Roundtrip price
$166
Distance
797 mi
Average flight time
2 hours 10 mins

Chicago to Panama City Flights

The cheapest times to fly from Chicago to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Chicago to Panama City are during the month of January. You can find some of the cheapest flights from Chicago to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Chicago to Panama City

Sunday is one of the best days to book for cheap flights from Chicago to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Chicago to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Chicago to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $115 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Chicago to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Chicago to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Midway Intl. Airport (MDW) to Northwest Florida Beaches Intl. Airport (ECP) cost?
Secure a cheap one-way flight from $115 or cheap return flight from $166 from Midway Intl. Airport (MDW) to Northwest Florida Beaches Intl. Airport (ECP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Midway Intl. Airport (MDW) to Northwest Florida Beaches Intl. Airport (ECP)?
January is the least expensive month to fly from MDW to ECP. Traveling during quieter months is often the key to scoring lower fares.
What is the cheapest airline that flies from Midway Intl. Airport (MDW) to Northwest Florida Beaches Intl. Airport (ECP)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest MDW to ECP flight.
How many flights per day from Midway Intl. Airport (MDW) to Northwest Florida Beaches Intl. Airport (ECP)?
You'll have to take a flight with a layover when traveling from Midway Intl. Airport (MDW) to Northwest Florida Beaches Intl. Airport (ECP). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to discover an option that works for you.
What day of the week has the most flights from MDW to ECP?
Typically you'll find the greatest selection of flight options on a Friday. Tuesdays are often the quietest.* But this can vary based on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What airline has the least delays from MDW to ECP?
Consider booking with Southwest Airlines if you'd like to go straight from Midway Intl. Airport (MDW) to Northwest Florida Beaches Intl. Airport (ECP) without any holdups. This carrier has the best track record for punctuality, with an on-time score of 82%. Want real-time updates? You can check your flight status using the Expedia App.
What is the best time to fly from Midway Intl. Airport (MDW) to Northwest Florida Beaches Intl. Airport (ECP)?
Book a flight from Midway Intl. Airport (MDW) to Northwest Florida Beaches Intl. Airport (ECP) that takes off before 3 PM to reduce the risk of cancellations and delays. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Panama City from Midway Intl. Airport (MDW)?
If you're flying on a direct flight from Midway Intl. Airport (MDW) to Panama City, Northwest Florida Regional Airport (VPS) is the only airport you can touch down at.
Is it cheaper to buy a plane ticket from Midway Intl. Airport (MDW) to Northwest Florida Beaches Intl. Airport (ECP) last-minute?
Booking your ticket from MDW to ECP right before your journey is typically more expensive. However, if you're flexible with your itinerary, you could grab a cheap last-minute fare.
Is it cheaper to book a MDW to ECP flight and hotel package?
You'll generally save money by securing a MDW to ECP flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one convenient place. Once you've chosen your ideal flights and accommodations, consider other add-ons like car rentals, tours and activities.
Can I cancel or change the date of my flight from Midway Intl. Airport (MDW) to Northwest Florida Beaches Intl. Airport (ECP)?
If you reserved your MDW to ECP flight in the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the fare type you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for more details.

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*Available to One Key members.