Find 5 Star Hotels in Palermo from $65

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Compare Palermo 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Palermo 5-star hotels

Soho Point Central
Garden

Soho Point Central

5.0 star property
8.8 out of 10, Excellent, (49)
"Really great property and location with welcoming and helpful staff. Nice living area and two bedrooms with comfortable beds. Highly recommend!"
$65 nightly
The price is $68
Sep 8 - Sep 9
Soho Point Central
BT Homes - FITZ ROY 2077
Outdoor spa tub

BT Homes - FITZ ROY 2077

5.0 star property
9.0 out of 10, Wonderful, (8)
"Es un departamento muy acogedor "
BT Homes - FITZ ROY 2077
Spacious New York-Style Apt in Palermo by BT Homes
Exterior

Spacious New York-Style Apt in Palermo by BT Homes

5.0 star property
Spacious New York-Style Apt in Palermo by BT Homes
Luxe Loft Art and Elegance in the Heart of Palermo by BT Homes
Deluxe Apartment, 3 Bedrooms, Balcony, Pool View | Dining room

Luxe Loft Art and Elegance in the Heart of Palermo by BT Homes

5.0 star property
10.0 out of 10, Exceptional, (1)
"Great apartment in a great location. "
Luxe Loft Art and Elegance in the Heart of Palermo by BT Homes
Renovated and Modern Studio in Palermo by BT Homes
Apartment, Balcony, City View | Dining room

Renovated and Modern Studio in Palermo by BT Homes

5.0 star property
10.0 out of 10, Exceptional, (3)
"I like the neighborhood "
Renovated and Modern Studio in Palermo by BT Homes
Spacious and modern Studio in Palermo by BT Homes
Outdoor spa tub

Spacious and modern Studio in Palermo by BT Homes

5.0 star property
6.0 out of 10, (2)
"Everything was amazing in general. The only things I can think of that could’ve been better are: - sometimes the lobby smelled really funky/bad; there’s a cleaning service there daily and it’s usually okay, but sometimes it’s an unfortunate smell. Maybe some scenting in the lobby would help avoid it. - I wish body lotion was provided. Shampoo, conditioner and body wash was plentiful and really great, adding lotion would make it complete. - extra trash bags. The trash cans are small and can...
Spacious and modern Studio in Palermo by BT Homes
Deaf Twins 2B Botanico Super Calido
Exterior

Deaf Twins 2B Botanico Super Calido

5.0 star property
10.0 out of 10, Exceptional, (1)
"Excelente todo"
Deaf Twins 2B Botanico Super Calido
Hollywood Suites & Lofts 2 - Las Suites
Breakfast area

Hollywood Suites & Lofts 2 - Las Suites

5.0 star property
8.4 out of 10, Very Good, (59)
Hollywood Suites & Lofts 2 - Las Suites
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Palermo.
Casa Joseph

Casa Joseph

4600 Charcas, Buenos Aires
$62 nightly
The price is $65 total per night from Sep 7 to Sep 8
$65 total
Sep 7 - Sep 8
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Palermo

Art enthusiasts, fashionistas, gourmands, nature lovers and partygoers frequent this chic and sprawling neighborhood loved for its tree-lined streets and parks.

See all hotels in Palermo
Japanese Garden showing a pond and a park

Top Palermo Hotel Reviews

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Frequently asked questions

How much does it cost to stay in a 5-star hotel in Palermo?
You can find a range of pricing options for a 5-star hotel in Palermo on Expedia. The amount you pay will depend on when you plan to travel, trip length and other factors. Compare available accommodations for your desired dates and make use of our pricing and other filters to discover the perfect luxury stay.

  • Search for the lowest price per night from $65

What makes a hotel 5 stars in Palermo?
Flawless guest service is the foundation of every 5-star hotel in Palermo. From the second you arrive, staff attend to your every need, whether recommending activities or providing in-room massage treatments. Additionally, hotels must feature top-rate conveniences to qualify for a 5-star rating. These can include luxury baths, a wellness center, swimming pools, fine dining restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Palermo?
Use our filter tool to find a luxurious getaway in Palermo where everything you need is included. Next, narrow down your results for accommodations that have 5 stars and are deemed "All inclusive." The first thing on the agenda at these stays? Pure indulgence and relaxation.