Name: Comfort Inn & Suites Florence Center Area
Price range: $113 total
Rating: 9

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC

$62 nightly

$70 total

Dec 14 - Dec 15

Total with taxes and fees

Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

8.6/10 Excellent! (2,486 reviews)

Basic place to stay if you need to get off the highway and take a nap

Reviewed on Dec 12, 2025

Park Inn by Radisson Florence, SC

1729 Mandeville Road Florence SC

$94 nightly

$105 total

Dec 14 - Dec 15

Total with taxes and fees

Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...

8.8/10 Excellent! (2,194 reviews)

Everything was okay except we were on the 2nd floor and the guest above us were heavy steppers and kept pacing. It was disturbing while trying to fall asleep. But the late check-out of 12 noon made up for it.

Reviewed on Dec 6, 2025

Comfort Inn & Suites Florence Center Area

527 Woody Jones Blvd Florence SC

$101 nightly

$113 total

Jan 11 - Jan 12, 2026

Total with taxes and fees

Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...

9/10 Wonderful! (1,162 reviews)

Easy check in. Room was very clean. Easy on site parking.

Reviewed on Dec 10, 2025

See all 136 properties in Effingham

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Spacious 4BR Home Near Florence – Ideal for Nurses & Long-Term Stays

Effingham SC

Stay at this vacation home in Effingham. Enjoy laundry facilities and air conditioning. Popular attractions Greenwood Baseball Park and Playground and Old Greenwood ...

Secret SC Cabin on 100 acres Hot Tub Large Pond

Marion SC

Book a stay at this family-friendly cabin in Marion. Enjoy a water park, laundry facilities, and patios.

9.4/10 Exceptional! (109 reviews)

Host was very responsive. Cabin was very quaint and cozy. We thoroughly enjoyed the fireplace and just relaxing!

Reviewed on Dec 10, 2025

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

Florence SC

Stay at this vacation home in Florence. Enjoy a garden, laundry facilities, and patios. Popular attractions Regal Swamp Fox and Florence Veterans Park are located ...

10/10 Exceptional! (35 reviews)

Very welcoming. We have stayed at many rentals. This one, is by far the best. The home is exactly as described. It is clean and very comfortable. We make the trip from Fl to PA a few times a year. This is a perfect rental for the half way point.

Reviewed on Dec 1, 2025

See all properties in Effingham

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.