Osco Vacation Rentals

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Vacation Rentals in Osco

3BR/2BA Beauty near TBK sports complex. Right off I74, close to everything!

10.0 out of 10, Exceptional, (30)
"Our stay was very nice! Everything we needed and easy to find!! Would definitely recommend this home!"
$274 nightly
The price is $307
Sep 7 - Sep 8
Total with taxes and fees
3BR/2BA Beauty near TBK sports complex. Right off I74, close to everything!

Minutes from anywhere

10.0 out of 10, Exceptional, (117)
"Great stay!! Location was super convenient, host was easy to communicate with, space was clean & had everything we needed plus some! Very much recommend this spot! "
$80 nightly
The price is $85
Sep 14 - Sep 15
Total with taxes and fees
Minutes from anywhere

Island House On Mississippi River

8.0 out of 10, Very Good, (35)
"Nice weekend away from home with the guys. View is great and we had beautiful weather. "
Island House On Mississippi River

Enchanting river front spot with deck and Tiki bar in charming Hampton, Illinois

10.0 out of 10, Exceptional, (5)
"An historic old general store that has been converted and updated to a modern, fun apartment. The back "Tiki Bar Deck" is literally "spitting distance" from the banks of the Mississippi River. the interior is completely modern with updated appliances, 4 TV's, an interior bar and a very comfortable living area. Also, the property is right on the river walk/bike trail. I have stayed at this property three times now and always go back when I am in the area. I highly recommend this property "
$140 nightly
The price is $148
Sep 10 - Sep 11
Total with taxes and fees
Enchanting river front spot with deck and Tiki bar in charming Hampton, Illinois

Home on Historic Campbell's Island with Mighty Mississippi River in the backyard

9.4 out of 10, Exceptional, (6)
$193 nightly
The price is $205
Sep 12 - Sep 13
Total with taxes and fees
Home on Historic Campbell's Island with Mighty Mississippi River in the backyard

Historical riverfront home in beautiful LeClaire. Kid and pet friendly!

9.4 out of 10, Exceptional, (9)
"We stayed one night to be in town for a friend’a birthday party and it was perfect for us. Cute place, great location, comfy bed!"
$205 nightly
The price is $230
Sep 7 - Sep 8
Total with taxes and fees
Historical riverfront home in beautiful LeClaire. Kid and pet friendly!

Charming 1920s, pet friendly home, centrally located!

9.2 out of 10, Wonderful, (26)
"Charming older home great when traveling with a pet. Host was very accommodating and responsive. "
$202 nightly
The price is $226
Sep 7 - Sep 8
Total with taxes and fees
Charming 1920s, pet friendly home, centrally located!

Awesome 3 Bedroom River Front Retreat right on the water!

10.0 out of 10, Exceptional, (25)
"Everything about this property was amazing. "
Awesome 3 Bedroom River Front Retreat right on the water!

Quiet neighborhood surrounded by parks near multipurpose trail through QC

10.0 out of 10, Exceptional, (36)
"Very clean and well maintained property. More than enough sheets, blankets, pillows, toiletries, silverware, ect..... So many rentals are barebones, this place has everything you'd need and then some. "
Quiet neighborhood surrounded by parks near multipurpose trail through QC

Pet Friendly & Spacious 3 BR in Silvis + Garage

10.0 out of 10, Exceptional, (4)
"Everything was as described. Great place for a quick 2 night stay. Thank you!"
Pet Friendly & Spacious 3 BR in Silvis + Garage

Renwick Mansion Guest House

9.6 out of 10, Exceptional, (81)
"Our stay was great! The owners were very friendly and helpful. The house is beautiful and inviting. It is in a great location for things to do. We would definitely stay here again!"
Renwick Mansion Guest House

The Nelson Lofts - Unit 7 (2 BR)

10.0 out of 10, Exceptional, (23)
"Clean place right next to multiple breweries "
$247 nightly
The price is $277
Sep 7 - Sep 8
Total with taxes and fees
The Nelson Lofts - Unit 7 (2 BR)

Riverfront Cabin:Wrap Around Deck & 3 Season Room

9.4 out of 10, Exceptional, (32)
"The property is meticulously maintained. The views of the river were claming after a long day of travel, the cabin was extremely comfortable, quiet and relaxing. Everything you could possibly need is present. My opinion is this place is a bargain for the price. Definately beats a hotel hands down. If I return to the area, I will definately book again! Thank you for your hospitality "
Riverfront Cabin:Wrap Around Deck & 3 Season Room

River Front House

8.6 out of 10, Excellent, (17)
"The owner was easy to get in touch with and very helpful. My coworker and I stayed here for a 3 week job."
$210 nightly
The price is $223
Sep 7 - Sep 8
Total with taxes and fees
River Front House

Rustic and Secluded 1 Bedroom Cabin Retreat. Located on Private Stocked Pond.

10.0 out of 10, Exceptional, (52)
"We loved our stay. Clean, quiet, and the owners were very accommodating to our needs. We plan to be back next year. "
Rustic and Secluded 1 Bedroom Cabin Retreat. Located on Private Stocked Pond.

Relax on the Rock River in fall, book our cozy 1-bedroom cabin!

9.6 out of 10, Exceptional, (30)
"I enjoyed everything about this quaint little cabin. It was the perfect way to peacefully enjoy the outdoors, watching the river flow, while sitting on the deck, by the fire. "
Relax on the Rock River in fall, book our cozy 1-bedroom cabin!

Moline 1 BR Near TaxSlayer and Downtown

7.6 out of 10, Good, (12)
"This home is pretty bare bones, but it was perfect for our needs! We really just needed a place to rest our heads between hanging out with family and a backyard for our dog to run around. We did have difficulty figuring out the lock, but the host was quick to answer our call and very polite and helpful! The only disappointment was that the coffee pot didn't work. If you just need a no frills place for a night or two, this is a great spot!"
Moline 1 BR Near TaxSlayer and Downtown

Quiet country home close to tbk sports complex

9.6 out of 10, Exceptional, (32)
"Was a great place for a group of friends on a weekend trip. "
Quiet country home close to tbk sports complex

Riverboat Paradise

10.0 out of 10, Exceptional, (42)
"This was a beautiful property. I was a lil worried about it being by the train tracks, but it was very quiet inside the apartment. Would absolutely stay again!"
Riverboat Paradise

Experience a 3 bedroom historic apartment Rock Island, IL

10.0 out of 10, Exceptional, (1)
"The apartment was wonderful, a step back in time! The beds were comfortable and the apartment was so charming. The gardens were so pretty, we enjoyed the peace and quiet of the area. Definitely would stay again! "
$372 nightly
The price is $417
Sep 7 - Sep 8
Total with taxes and fees
Experience a 3 bedroom historic apartment Rock Island, IL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Osco Hotel Reviews

Find out more about Osco

Find out more about Osco

Everything you need to know about Osco vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Osco vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Osco vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Osco vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Osco. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Osco in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $85 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Osco rentals

At Expedia, we put the best Osco vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Osco rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Osco vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Osco. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Osco?

Yes, you can find vacation rentals near popular local attractions in Osco, or you can select a secluded option if you'd like a relaxing place to stay.

What are some of the best vacation home rentals in Osco?

3BR/2BA Beauty near TBK sports complex. Right off I74, close to everything! : Visitors like this Osco vacation home rental. It is equipped with a fireplace, air-conditioning, and laundry facilities to help you feel comfortable during your stay.

What’s there to see and do in Osco?

Explore the area and family-friendly sights such as Niabi Zoo, or get out into nature at a spot like Illiniwek Forest Preserve. TPC Deere Run Golf Course and Deere and Company World Headquarters are a couple of places you'll find in the larger area.

What’s a vacation rental in Osco like?

Vacation rentals are privately owned properties you can stay in for short or long periods in Osco. Vacation rentals offer extras such as hot tubs, fire pits, and patios so you'll have a home away from home. If you're concerned about a sanitized environment, vacation rentals can provide a sense of safety away from public hotel elevators and busy concierge desks while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a popular choice for families.