$160 Cheap Flights from Des Moines (DSM) to Lafayette (LFT)

View $160 flight on Thu, Jan 1, 2026Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Lafayette Regional Airport (LFT)

Cheap Flights from Des Moines to Lafayette (DSM-LFT)

Prices were available within the past 7 days and start at $160 for one-way flights and $249 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Nov 18 - Wed, Dec 3
DSM
Des Moines
LFT
Lafayette
$249 Roundtrip, found 6 days ago
$249
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Nov 18 from Des Moines to Lafayette, returning Wed, Dec 3, priced at $249 found 6 days ago
Delta
Sun, Nov 16 - Wed, Dec 3
DSM
Des Moines
LFT
Lafayette
$254 Roundtrip, found 6 days ago
$254
Roundtrip
found 6 days ago
Select Delta flight, departing Sun, Nov 16 from Des Moines to Lafayette, returning Wed, Dec 3, priced at $254 found 6 days ago
Delta
Sun, Nov 9 - Tue, Nov 18
DSM
Des Moines
LFT
Lafayette
$259 Roundtrip, found 6 days ago
$259
Roundtrip
found 6 days ago
Select Delta flight, departing Sun, Nov 9 from Des Moines to Lafayette, returning Tue, Nov 18, priced at $259 found 6 days ago
Delta
Mon, Nov 10 - Wed, Nov 26
DSM
Des Moines
LFT
Lafayette
$264 Roundtrip, found 5 days ago
$264
Roundtrip
found 5 days ago
Select Delta flight, departing Mon, Nov 10 from Des Moines to Lafayette, returning Wed, Nov 26, priced at $264 found 5 days ago
Delta
Sun, Nov 9 - Sat, Nov 15
DSM
Des Moines
LFT
Lafayette
$264 Roundtrip, found 6 days ago
$264
Roundtrip
found 6 days ago
Select Delta flight, departing Sun, Nov 9 from Des Moines to Lafayette, returning Sat, Nov 15, priced at $264 found 6 days ago
Delta
Sun, Nov 9 - Wed, Nov 26
DSM
Des Moines
LFT
Lafayette
$269 Roundtrip, found 5 days ago
$269
Roundtrip
found 5 days ago
Select Delta flight, departing Sun, Nov 9 from Des Moines to Lafayette, returning Wed, Nov 26, priced at $269 found 5 days ago
Delta
Mon, Nov 10 - Sat, Nov 15
DSM
Des Moines
LFT
Lafayette
$279 Roundtrip, found 5 days ago
$279
Roundtrip
found 5 days ago
Select Delta flight, departing Mon, Nov 10 from Des Moines to Lafayette, returning Sat, Nov 15, priced at $279 found 5 days ago
Delta
Thu, Nov 20 - Wed, Dec 3
DSM
Des Moines
LFT
Lafayette
$284 Roundtrip, found 6 days ago
$284
Roundtrip
found 6 days ago
Select Delta flight, departing Thu, Nov 20 from Des Moines to Lafayette, returning Wed, Dec 3, priced at $284 found 6 days ago
United
Tue, Nov 4 - Sun, Nov 9
DSM
Des Moines
LFT
Lafayette
$289 Roundtrip, found 6 days ago
$289
Roundtrip
found 6 days ago
Select United flight, departing Tue, Nov 4 from Des Moines to Lafayette, returning Sun, Nov 9, priced at $289 found 6 days ago
American Airlines
Fri, May 1 - Wed, May 6
DSM
Des Moines
LFT
Lafayette
$309 Roundtrip, found 1 day ago
$309
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, May 1 from Des Moines to Lafayette, returning Wed, May 6, priced at $309 found 1 day ago

Alternative airports near Lafayette

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lafayette Regional LFT. Cheapest and Closest option available. Average driving time to city center is 5 minutes. Flights from $264
LFT
Lafayette Regional
CheapestClosest
Average driving time to city center5 min
Flights from $264

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Lafayette Regional Airport (LFT) cost?
Lock in a cheap one-way flight from $160 or cheap return flight from $249 from Des Moines Intl. Airport (DSM) to Lafayette Regional Airport (LFT) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Lafayette Regional Airport (LFT)?
November is the cheapest month to fly from DSM to LFT. Avoiding peak travel times is often the key to scoring lower fares.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Lafayette Regional Airport (LFT)?
Use the filters on Expedia to compare different airlines and find the most affordable carrier that'll fly you from DSM to LFT. Then, sort your results by "Price (lowest to highest)" to score a great deal.
How many flights per day from Des Moines Intl. Airport (DSM) to Lafayette Regional Airport (LFT)?
You'll need to catch a flight with a layover if you're traveling from Des Moines Intl. Airport (DSM) to Lafayette Regional Airport (LFT). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from DSM to LFT?
Typically you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can change based on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Lafayette Regional Airport (LFT)?
To avoid potential delays on the Des Moines Intl. Airport (DSM) to Lafayette Regional Airport (LFT) route, aim to travel before 3 PM. Later flights have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Lafayette Regional Airport (LFT) last-minute?
Booking your plane ticket from DSM to LFT right before your getaway is usually more expensive. But if there's some wiggle room with your departure dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a DSM to LFT flight and hotel package?
Securing a DSM to LFT flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip in one place. Pick from our extensive range of stays and then add flights, car rentals and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Lafayette Regional Airport (LFT)?
In most instances, you're able to cancel or reschedule your DSM to LFT flight. However, additional fees may apply, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline's guidelines and fees on flight changes, or if you need further information, go to our Customer Service portal.

Travel information

Origin airport
Des Moines Intl.
Destination airport
Lafayette Regional
Airlines serving
American Airlines, Delta, United
Roundtrip price
$248
Distance
788 mi

Book with confidence

Des Moines to Lafayette Flights

The cheapest times to fly from Des Moines to Lafayette

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Lafayette are during the month of November. You can find some of the cheapest flights from Des Moines to Lafayette with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Lafayette

Sunday is one of the best days to book for cheap flights from Des Moines to Lafayette: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Lafayette

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Lafayette in 2025. You can also book with separate airlines for your outbound and return journeys, from $160 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Lafayette flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Lafayette airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to Lafayette Flights

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*Available to One Key members.