$375 Cheap Flights from Guadalajara (GDL) to Panama City (PTY)

View $375 flight on Tue, Aug 26, 2025Opens in a new window

Popular airlines from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Tocumen Intl. Airport (PTY)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • one key icon

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Guadalajara to Panama City (GDL-PTY)

Prices were available within the past 7 days and start at $375 for one-way flights and $427 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Thu, Aug 28 - Fri, Sep 5
GDL
Guadalajara
PTY
Panama City
$427 Roundtrip, found 3 hours ago
$427
Roundtrip
found 3 hours ago
Select Aeromexico flight, departing Thu, Aug 28 from Guadalajara to Panama City, returning Fri, Sep 5, priced at $427 found 3 hours ago
Copa
Fri, Oct 17 - Fri, Nov 14
GDL
Guadalajara
PTY
Panama City
$430 Roundtrip, found 1 day ago
$430
Roundtrip
found 1 day ago
Select Copa flight, departing Fri, Oct 17 from Guadalajara to Panama City, returning Fri, Nov 14, priced at $430 found 1 day ago
Aeromexico
Wed, Sep 10 - Wed, Sep 17
GDL
Guadalajara
PTY
Panama City
$431 Roundtrip, found 23 hours ago
$431
Roundtrip
found 23 hours ago
Select Aeromexico flight, departing Wed, Sep 10 from Guadalajara to Panama City, returning Wed, Sep 17, priced at $431 found 23 hours ago
Aeromexico
Sat, Jan 10 - Sat, Jan 24
GDL
Guadalajara
PTY
Panama City
$436 Roundtrip, found 4 days ago
$436
Roundtrip
found 4 days ago
Select Aeromexico flight, departing Sat, Jan 10 from Guadalajara to Panama City, returning Sat, Jan 24, priced at $436 found 4 days ago
Aeromexico
Fri, Oct 17 - Fri, Nov 14
GDL
Guadalajara
PTY
Panama City
$457 Roundtrip, found 1 day ago
$457
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Fri, Oct 17 from Guadalajara to Panama City, returning Fri, Nov 14, priced at $457 found 1 day ago
Copa
Wed, Aug 27 - Thu, Aug 28
GDL
Guadalajara
PTY
Panama City
$475 Roundtrip, found 3 days ago
$475
Roundtrip
found 3 days ago
Select Copa flight, departing Wed, Aug 27 from Guadalajara to Panama City, returning Thu, Aug 28, priced at $475 found 3 days ago
Copa
Tue, Oct 14 - Sun, Nov 16
GDL
Guadalajara
PTY
Panama City
$478 Roundtrip, found 1 day ago
$478
Roundtrip
found 1 day ago
Select Copa flight, departing Tue, Oct 14 from Guadalajara to Panama City, returning Sun, Nov 16, priced at $478 found 1 day ago
Aeromexico
Fri, Oct 17 - Fri, Nov 14
GDL
Guadalajara
PTY
Panama City
$483 Roundtrip, found 1 day ago
$483
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Fri, Oct 17 from Guadalajara to Panama City, returning Fri, Nov 14, priced at $483 found 1 day ago
American Airlines
Fri, Sep 19 - Wed, Sep 24
GDL
Guadalajara
PTY
Panama City
$1,125 Roundtrip, found 1 day ago
$1,125
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Sep 19 from Guadalajara to Panama City, returning Wed, Sep 24, priced at $1,125 found 1 day ago
United
Fri, Oct 31 - Tue, Nov 4
GDL
Guadalajara
PTY
Panama City
$1,137 Roundtrip, found 11 hours ago
$1,137
Roundtrip
found 11 hours ago
Select United flight, departing Fri, Oct 31 from Guadalajara to Panama City, returning Tue, Nov 4, priced at $1,137 found 11 hours ago

Find the cheapest month to fly from Guadalajara (GDL) to Panama City (PTY)

June is typically the cheapest month to fly

From $362 - $1,089 per traveler.

Graph displaying average flight prices per month

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $427
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $427
Flights from Guadalajara (GDL) to Panama City (PTY)
Origin airport
Don Miguel Hidalgo y Costilla Intl.
Destination airport
Tocumen Intl.
Airlines serving
Aeromexico, American Airlines, Copa, Delta, United
Roundtrip price
$426
Distance
1779 mi
Average flight time
4 hours 14 mins

Guadalajara to Panama City Flights

The cheapest times to fly from Guadalajara to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Guadalajara to Panama City are during the month of August. You can find some of the cheapest flights from Guadalajara to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Guadalajara to Panama City

Sunday is one of the best days to book for cheap flights from Guadalajara to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Guadalajara to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Guadalajara to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $375 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Guadalajara to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Guadalajara to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Tocumen Intl. Airport (PTY) cost?
You can find cheap return fares from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Tocumen Intl. Airport (PTY) starting from $477. Book your seat and get ready for takeoff. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Copa flight leaving GDL on August 15 2025 and touching down at PTY. The price was last updated on July 23 2025 and has not changed since.
What is the cheapest month to fly from GDL to PTY?
The cheapest flights from GDL to PTY are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Tocumen Intl. Airport (PTY)?
Fly directly from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Tocumen Intl. Airport (PTY) on a Copa Airlines flight.
What is the cheapest airline that flies from GDL to PTY?
With fares starting at $676 for a one-way flight from GDL to PTY, Copa is currently the cheapest airline for this route. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from GDL on October 4 2025. Prices were last updated on July 23 2025 and have not changed since.
How many flights per day from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Tocumen Intl. Airport (PTY)?
On average, Don Miguel Hidalgo y Costilla Intl. Airport (GDL) offers 4 nonstop flights to Tocumen Intl. Airport (PTY) weekly. For more choice, take advantage of Expedia's filter tool to search for flights with a layover. Squeeze in a visit to another location or simply break up your journey.
What are the most popular departure times for flights from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Tocumen Intl. Airport (PTY)?
More people fly between GDL and PTY at 12 AM than at any other point in the day. Rather go when it's quieter? Consider flying outside peak hours and you're likely to save on your fare as well.
What day of the week has the most flights from GDL to PTY?
If you travel on a Friday, you'll get the largest range of options for flights from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Tocumen Intl. Airport (PTY).
What is the earliest flight from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Tocumen Intl. Airport (PTY)?
Don Miguel Hidalgo y Costilla Intl. Airport (GDL)'s earliest flight to Tocumen Intl. Airport (PTY) is at approximately 12:01AM UTC-6. With a total journey time of 4h 8m, you'll touch down at around 5:09AM UTC-5.
How long does it take to fly from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Tocumen Intl. Airport (PTY)?
Flights from GDL to PTY have an average travel time of 4 hours and 8 minutes. The distance between these two airports is 1,800 mi.
What airline has the least delays from GDL to PTY?
Copa Airlines has the strongest track record for on-time direct flights from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Tocumen Intl. Airport (PTY), with an on-time rating of 92%. Use the Expedia App to see your flight schedule before you jet off and get real-time alerts about any changes.
What is the best time to fly from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Tocumen Intl. Airport (PTY)?
To avoid possible delays on the Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Tocumen Intl. Airport (PTY) route, aim to travel before 3 PM. Departures after this time have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Panama City from Don Miguel Hidalgo y Costilla Intl. Airport (GDL)?
If you're taking a direct flight from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Panama City, Tocumen Intl. Airport (PTY) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Tocumen Intl. Airport (PTY) last-minute?
Last-minute fares from GDL to PTY are typically more expensive. For the lowest prices, start looking for flights well in advance. That said, if your travel plans are flexible, it's possible to score a cheap ticket right before you leave.
Is it cheaper to book a GDL to PTY flight and hotel package?
Opting for a GDL to PTY flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Tocumen Intl. Airport (PTY)?
Typically, you're able to reschedule or cancel your GDL to PTY flight. However, there may be additional fees, especially if you made your booking over 24 hours ago. Double-check your itinerary for the airline's fees and policies on flight changes, or if you'd like more details, visit our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.