$96 Cheap Flights from Istanbul (IST) to Brussels (BRU)

View $96 flight on Sun, Dec 14, 2025Opens in a new window

Popular airlines from Istanbul Airport (IST) to Brussels Airport (BRU)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • one key icon

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Istanbul to Brussels (IST-BRU)

Prices were available within the past 7 days and start at $96 for one-way flights and $242 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aegean
Sun, Nov 9 - Thu, Nov 13
IST
Istanbul
BRU
Brussels
$242 Roundtrip, found 18 hours ago
$242
Roundtrip
found 18 hours ago
Select Aegean flight, departing Sun, Nov 9 from Istanbul to Brussels, returning Thu, Nov 13, priced at $242 found 18 hours ago
Lufthansa
Fri, Oct 3 - Tue, Oct 14
IST
Istanbul
BRU
Brussels
$268 Roundtrip, found 5 days ago
$268
Roundtrip
found 5 days ago
Select Lufthansa flight, departing Fri, Oct 3 from Istanbul to Brussels, returning Tue, Oct 14, priced at $268 found 5 days ago
LOT-Polish Airlines
Thu, Mar 12 - Tue, Mar 17
IST
Istanbul
BRU
Brussels
$272 Roundtrip, found 1 day ago
$272
Roundtrip
found 1 day ago
Select LOT-Polish Airlines flight, departing Thu, Mar 12 from Istanbul to Brussels, returning Tue, Mar 17, priced at $272 found 1 day ago
Turkish Airlines
Tue, Dec 9 - Tue, Jan 13
IST
Istanbul
BRU
Brussels
$289 Roundtrip, found 2 days ago
$289
Roundtrip
found 2 days ago
Select Turkish Airlines flight, departing Tue, Dec 9 from Istanbul to Brussels, returning Tue, Jan 13, priced at $289 found 2 days ago
SKY express
Mon, Aug 4 - Wed, Aug 6
IST
Istanbul
BRU
Brussels
$322 Roundtrip, found 16 hours ago
$322
Roundtrip
found 16 hours ago
Select SKY express flight, departing Mon, Aug 4 from Istanbul to Brussels, returning Wed, Aug 6, priced at $322 found 16 hours ago
Vueling Airlines
Tue, Dec 9 - Tue, Jan 13
IST
Istanbul
BRU
Brussels
$322 Roundtrip, found 2 days ago
$322
Roundtrip
found 2 days ago
Select Vueling Airlines flight, departing Tue, Dec 9 from Istanbul to Brussels, returning Tue, Jan 13, priced at $322 found 2 days ago
Air Serbia
Wed, Oct 8 - Wed, Oct 8
IST
Istanbul
BRU
Brussels
$343 Roundtrip, found 15 hours ago
$343
Roundtrip
found 15 hours ago
Select Air Serbia flight, departing Wed, Oct 8 from Istanbul to Brussels, returning Wed, Oct 8, priced at $343 found 15 hours ago
British Airways
Thu, Mar 12 - Tue, Mar 17
IST
Istanbul
BRU
Brussels
$374 Roundtrip, found 1 day ago
$374
Roundtrip
found 1 day ago
Select British Airways flight, departing Thu, Mar 12 from Istanbul to Brussels, returning Tue, Mar 17, priced at $374 found 1 day ago
Tarom-Romanian Air Transport
Sun, Nov 9 - Thu, Nov 13
IST
Istanbul
BRU
Brussels
$376 Roundtrip, found 18 hours ago
$376
Roundtrip
found 18 hours ago
Select Tarom-Romanian Air Transport flight, departing Sun, Nov 9 from Istanbul to Brussels, returning Thu, Nov 13, priced at $376 found 18 hours ago
KM Malta Airlines
Tue, Dec 9 - Tue, Jan 13
IST
Istanbul
BRU
Brussels
$475 Roundtrip, found 2 days ago
$475
Roundtrip
found 2 days ago
Select KM Malta Airlines flight, departing Tue, Dec 9 from Istanbul to Brussels, returning Tue, Jan 13, priced at $475 found 2 days ago

Find the cheapest month to fly from Istanbul (IST) to Brussels (BRU)

May is typically the cheapest month to fly

From $108 - $288 per traveler.

Graph displaying average flight prices per month

Alternative airports near Brussels

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Brussels South Charleroi CRL. Average driving time to city center is 42 minutes. Flights from $374
CRL
Brussels South Charleroi
Average driving time to city center42 min
Flights from $374
Flights from Istanbul (SAW) to Charleroi (CRL)
Origin airport
Sabiha Gokcen Intl.
Destination airport
Brussels South Charleroi
Airlines serving
Aegean, Air Baltic, Air Serbia, British Airways, ITA Airways, Iberia, KLM, KM Malta Airlines, LOT-Polish Airlines, Lufthansa, SKY express, Tarom-Romanian Air Transport, Turkish Airlines
Roundtrip price
$185
Distance
1360 mi
Average flight time
2 hours 30 mins

Istanbul to Brussels Flights

The cheapest times to fly from Istanbul to Brussels

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Istanbul to Brussels are during the month of November. You can find some of the cheapest flights from Istanbul to Brussels with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Istanbul to Brussels

Sunday is one of the best days to book for cheap flights from Istanbul to Brussels: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Istanbul to Brussels

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Istanbul to Brussels in 2025. You can also book with separate airlines for your outbound and return journeys, from $96 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Istanbul to Brussels flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Istanbul to Brussels airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Istanbul (IST) to Brussels - National Airport (BRU) cost?
Cheap round-trip flights from Istanbul (IST) to Brussels - National Airport (BRU) start at $303. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Turkish Airlines and Pegasus Airlines flight leaving IST on August 6 2025 and touching down at BRU. The price was last updated on July 23 2025 and has not changed since.
What is the cheapest month to fly from IST to BRU?
The cheapest flights from IST to BRU are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Istanbul (IST) to Brussels - National Airport (BRU)?
There are no direct routes from Istanbul (IST) to Brussels - National Airport (BRU). However, you'll find other airports that have nonstop flights. Begin your journey at Ataturk Intl. Airport (IST) and head straight to Brussels without a layover.
What is the cheapest airline that flies from IST to BRU?
With fares starting at $184 for a one-way flight from IST to BRU, Turkish Airlines is currently the cheapest carrier on this route. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from IST on October 14 2025. Prices were last updated on July 23 2025 and have not changed since.
How many flights per day from Istanbul (IST) to Brussels - National Airport (BRU)?
There aren't any daily nonstop flights departing from Istanbul (IST) to Brussels - National Airport (BRU). But you can opt for flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be cruising above the clouds in no time.
What day of the week has the most flights from IST to BRU?
Typically you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can change depending on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Istanbul (IST) to Brussels - National Airport (BRU)?
To avoid possible delays on the Istanbul (IST) to Brussels - National Airport (BRU) route, aim to fly before 3 PM. Later departures have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Istanbul (IST) to Brussels - National Airport (BRU) last-minute?
Booking your flight from IST to BRU shortly before your journey is typically more expensive. However, if there's some wiggle room with your itinerary, you could bag a cheap last-minute fare.
Is it cheaper to book an IST to BRU flight and hotel package?
Compared with arranging flights and hotels separately, booking an IST to BRU flight and hotel package with Expedia could result in significant savings. What's more, having everything in one easy place takes the hassle out of planning your trip. Simply secure your flights and select from our extensive range of hotels, then tailor your trip with other add-ons like activities, tours and car rentals.
Can I cancel or change the date of my flight from Istanbul (IST) to Brussels - National Airport (BRU)?
It's usually possible to reschedule or cancel your IST to BRU flight. However, if it's been more than 24 hours since booking, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more information on our Customer Service portal.

Explore a world of travel with Expedia

Brussels nearby Airports

Charleroi

Istanbul to Brussels South Charleroi
$185.47

Antwerp

Istanbul nearby Airports

Istanbul

Sabiha Gokcen Intl. to Brussels
$185.47
*Available to One Key members.