$254 Cheap Flights from Mobile (MOB) to Columbus (CMH)

View $254 flight on Mon, Jun 8, 2026Opens in a new window

Popular airlines from Mobile Regional Airport (MOB) to John Glenn Columbus Intl. Airport (CMH)

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Cheap Flights from Mobile to Columbus (MOB-CMH)

Prices were available within the past 7 days and start at $254 for one-way flights and $311 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Aug 5 - Tue, Aug 11
MOB
Mobile
CMH
Columbus
$311 Roundtrip, found 11 hours ago
$311
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Wed, Aug 5 from Mobile to Columbus, returning Tue, Aug 11, priced at $311 found 11 hours ago
Delta
Wed, Aug 5 - Tue, Aug 11
MOB
Mobile
CMH
Columbus
$311 Roundtrip, found 11 hours ago
$311
Roundtrip
found 11 hours ago
Select Delta flight, departing Wed, Aug 5 from Mobile to Columbus, returning Tue, Aug 11, priced at $311 found 11 hours ago
United
Wed, Aug 5 - Tue, Aug 11
MOB
Mobile
CMH
Columbus
$311 Roundtrip, found 11 hours ago
$311
Roundtrip
found 11 hours ago
Select United flight, departing Wed, Aug 5 from Mobile to Columbus, returning Tue, Aug 11, priced at $311 found 11 hours ago
United
Wed, Aug 5 - Tue, Aug 11
MOB
Mobile
CMH
Columbus
$316 Roundtrip, found 11 hours ago
$316
Roundtrip
found 11 hours ago
Select United flight, departing Wed, Aug 5 from Mobile to Columbus, returning Tue, Aug 11, priced at $316 found 11 hours ago
United
Wed, Aug 5 - Mon, Aug 10
MOB
Mobile
CMH
Columbus
$320 Roundtrip, found 22 hours ago
$320
Roundtrip
found 22 hours ago
Select United flight, departing Wed, Aug 5 from Mobile to Columbus, returning Mon, Aug 10, priced at $320 found 22 hours ago
Delta
Tue, Aug 4 - Mon, Aug 10
MOB
Mobile
CMH
Columbus
$327 Roundtrip, found 2 days ago
$327
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Aug 4 from Mobile to Columbus, returning Mon, Aug 10, priced at $327 found 2 days ago
United
Sat, May 2 - Sat, May 9
MOB
Mobile
CMH
Columbus
$334 Roundtrip, found 5 days ago
$334
Roundtrip
found 5 days ago
Select United flight, departing Sat, May 2 from Mobile to Columbus, returning Sat, May 9, priced at $334 found 5 days ago
United
Sat, May 2 - Sat, May 9
MOB
Mobile
CMH
Columbus
$339 Roundtrip, found 5 days ago
$339
Roundtrip
found 5 days ago
Select United flight, departing Sat, May 2 from Mobile to Columbus, returning Sat, May 9, priced at $339 found 5 days ago
Delta
Fri, Aug 7 - Mon, Aug 10
MOB
Mobile
CMH
Columbus
$343 Roundtrip, found 2 days ago
$343
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Aug 7 from Mobile to Columbus, returning Mon, Aug 10, priced at $343 found 2 days ago
United
Wed, Aug 5 - Tue, Aug 11
MOB
Mobile
CMH
Columbus
$347 Roundtrip, found 11 hours ago
$347
Roundtrip
found 11 hours ago
Select United flight, departing Wed, Aug 5 from Mobile to Columbus, returning Tue, Aug 11, priced at $347 found 11 hours ago

Frequently asked questions

How much does a flight from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) cost?
You can find cheap one-way flights from $254 and cheap return flights from $311 Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) with Expedia. One-way flights typically cost between $242 and $710, and return flights often range between $326 and $1073. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
April is the cheapest month to fly from Mobile (MOB) to Columbus (CMH), with average return fares around $304. This price is about 16% lower than the average for the year, as spring travel often sees reduced demand. Other affordable months to consider are July and September.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
Enter MOB to CMH and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
American Airlines is one of the cheapest airlines offering connecting flights from Mobile, AL (MOB) to Columbus, OH (CMH), with round-trip tickets starting from around $248. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
To find a cheap flight from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
The best times to fly from Mobile, AL (MOB) to Columbus, OH (CMH) are April and September. Average return flight prices are around $304, making these months both affordable and convenient. These months typically see less travel demand, allowing for a smoother journey.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
The earliest flight from Mobile, AL (MOB) to Columbus, OH (CMH) generally departs at around 5:05 AM, operated by American Airlines. This seasonal service is available in November, allowing you to make the most of your travel day. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
The most popular departure times for flights from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) are in the early morning, from 6am to 9am. This time window accounts for about 24% of total traffic. Many major carriers, including Delta and United, offer flights during this period. Early departures are favored as they allow you to arrive in Columbus with plenty of time to explore the city.
How long does it take to fly from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
Flights from MOB to CMH with one stop typically take around 5 hours 20 minutes, covering approximately 711 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
First class seats are offered on the MOB to CMH route. First class cabins are available on:

  • Delta Air Lines
  • American Airlines
  • United Airlines

How do I earn miles on a Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) flight with Expedia?
It's easy to earn miles on a Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Columbus from Mobile Regional (MOB)?
From Mobile Regional (MOB), you can fly into John Glenn Columbus Intl. (CMH) and Columbus Metropolitan (CSG) in Columbus. Some flights may connect through major hubs like George Bush Intercontinental (IAH), Washington Dulles Intl. (IAD), Charlotte-Douglas Intl. (CLT) before reaching Columbus. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) at the last minute?
Typically, booking a last minute flight from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) flight and hotel package?
Securing a Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) Columbus Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
If you booked your Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Mobile Regional
Destination airport
John Glenn Columbus Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$310
Distance
710 mi

Book with confidence

Mobile to Columbus Flights

The cheapest times to fly from Mobile to Columbus

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mobile to Columbus are during the month of August. You can find some of the cheapest flights from Mobile to Columbus with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mobile to Columbus

Sunday is one of the best days to book for cheap flights from Mobile to Columbus: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mobile to Columbus

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mobile to Columbus in 2026. You can also book with separate airlines for your outbound and return journeys, from $254 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mobile to Columbus flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mobile to Columbus airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Mobile to Columbus Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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