$139 Cheap Flights from Myrtle Beach (MYR) to Guayaquil (GYE)

View $139 flight on Wed, Jan 7, 2026Opens in a new window

Popular airlines from Myrtle Beach Intl. Airport (MYR) to Jose Joaquin de Olmedo Intl. Airport (GYE)

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Cheap Flights from Myrtle Beach to Guayaquil (MYR-GYE)

Prices were available within the past 7 days and start at $139 for one-way flights and $339 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Tue, Jan 13 - Wed, Jan 14
MYR
Myrtle Beach
GYE
Guayaquil
$339 Roundtrip, found 3 days ago
$339
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Tue, Jan 13 from Myrtle Beach to Guayaquil, returning Wed, Jan 14, priced at $339 found 3 days ago
Spirit Airlines
Tue, Feb 3 - Tue, Feb 24
MYR
Myrtle Beach
GYE
Guayaquil
$352 Roundtrip, found 3 days ago
$352
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Tue, Feb 3 from Myrtle Beach to Guayaquil, returning Tue, Feb 24, priced at $352 found 3 days ago
Spirit Airlines
Mon, Dec 8 - Tue, Jan 13
MYR
Myrtle Beach
GYE
Guayaquil
$405 Roundtrip, found 3 days ago
$405
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Mon, Dec 8 from Myrtle Beach to Guayaquil, returning Tue, Jan 13, priced at $405 found 3 days ago
Spirit Airlines
Thu, Dec 25 - Wed, Dec 31
MYR
Myrtle Beach
GYE
Guayaquil
$443 Roundtrip, found 1 day ago
$443
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Thu, Dec 25 from Myrtle Beach to Guayaquil, returning Wed, Dec 31, priced at $443 found 1 day ago
Delta
Wed, Jan 14 - Wed, Jan 28
MYR
Myrtle Beach
GYE
Guayaquil
$534 Roundtrip, found 3 hours ago
$534
Roundtrip
found 3 hours ago
Select Delta flight, departing Wed, Jan 14 from Myrtle Beach to Guayaquil, returning Wed, Jan 28, priced at $534 found 3 hours ago
Delta
Sun, Jan 18 - Wed, Jan 28
MYR
Myrtle Beach
GYE
Guayaquil
$544 Roundtrip, found 3 hours ago
$544
Roundtrip
found 3 hours ago
Select Delta flight, departing Sun, Jan 18 from Myrtle Beach to Guayaquil, returning Wed, Jan 28, priced at $544 found 3 hours ago
United
Wed, Jan 21 - Thu, Feb 5
MYR
Myrtle Beach
GYE
Guayaquil
$552 Roundtrip, found 3 hours ago
$552
Roundtrip
found 3 hours ago
Select United flight, departing Wed, Jan 21 from Myrtle Beach to Guayaquil, returning Thu, Feb 5, priced at $552 found 3 hours ago
United
Tue, Mar 3 - Fri, Mar 13
MYR
Myrtle Beach
GYE
Guayaquil
$554 Roundtrip, found 3 days ago
$554
Roundtrip
found 3 days ago
Select United flight, departing Tue, Mar 3 from Myrtle Beach to Guayaquil, returning Fri, Mar 13, priced at $554 found 3 days ago
American Airlines
Mon, Dec 8 - Tue, Jan 13
MYR
Myrtle Beach
GYE
Guayaquil
$560 Roundtrip, found 3 days ago
$560
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Dec 8 from Myrtle Beach to Guayaquil, returning Tue, Jan 13, priced at $560 found 3 days ago
LATAM Airlines Group
Mon, Jan 26 - Wed, Feb 11
MYR
Myrtle Beach
GYE
Guayaquil
$633 Roundtrip, found 3 hours ago
$633
Roundtrip
found 3 hours ago
Select LATAM Airlines Group flight, departing Mon, Jan 26 from Myrtle Beach to Guayaquil, returning Wed, Feb 11, priced at $633 found 3 hours ago

Frequently asked questions

How much does a flight from Myrtle Beach Intl. Airport (MYR) to Jose Joaquin de Olmedo Intl. Airport (GYE) cost?
Secure a cheap one-way flight from $139 or cheap return flight from $339 from Myrtle Beach Intl. Airport (MYR) to Jose Joaquin de Olmedo Intl. Airport (GYE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Myrtle Beach Intl. Airport (MYR) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
The cheapest month to fly from MYR to GYE is January, when demand is low. Off-peak months are often when you'll find cheap fares for travel between these airports.
What is the cheapest airline that flies from Myrtle Beach Intl. Airport (MYR) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
To find the cheapest airline that'll fly you from MYR to GYE, use Expedia's filter tool. Tailor your search based on what's important to you, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Myrtle Beach Intl. Airport (MYR) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
You'll need to hop on a flight with a layover if you're traveling from Myrtle Beach Intl. Airport (MYR) to Jose Joaquin de Olmedo Intl. Airport (GYE). There are no daily direct flights on this route. However, just filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from MYR to GYE?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Myrtle Beach Intl. Airport (MYR) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
Opt for a flight from Myrtle Beach Intl. Airport (MYR) to Jose Joaquin de Olmedo Intl. Airport (GYE) that takes off before 3 PM to reduce the likelihood of delays. Departures after this time have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Myrtle Beach Intl. Airport (MYR) to Jose Joaquin de Olmedo Intl. Airport (GYE) last-minute?
Last-minute bookings from MYR to GYE are generally more expensive. For the best prices, start looking for flights early. That being said, if you're flexible with your travel plans, you may land a cheap fare right before your journey.
Is it cheaper to book a MYR to GYE flight and hotel package?
Compared with arranging flights and hotels separately, booking a MYR to GYE flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one easy place will take the hassle out of planning your trip. Just pick your flights and choose from our wide range of stays, then customize your trip with other add-ons like car rentals and activities.
Can I cancel or change the date of my flight from Myrtle Beach Intl. Airport (MYR) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
Typically, you can modify or cancel your MYR to GYE flight. However, additional fees may apply, especially if you made your booking over 24 hours ago. Check your itinerary for the airline's fees and rules on flight changes, or if you want further information, head to our Customer Service portal.

Travel information

Origin airport
Myrtle Beach Intl.
Destination airport
Jose Joaquin de Olmedo Intl.
Airlines serving
American Airlines, Delta, LATAM Airlines Group, Spirit Airlines, United
Roundtrip price
$338
Distance
2476 mi

Book with confidence

Myrtle Beach to Guayaquil Flights

The cheapest times to fly from Myrtle Beach to Guayaquil

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Myrtle Beach to Guayaquil are during the month of January. You can find some of the cheapest flights from Myrtle Beach to Guayaquil with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Myrtle Beach to Guayaquil

Sunday is one of the best days to book for cheap flights from Myrtle Beach to Guayaquil: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Myrtle Beach to Guayaquil

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Myrtle Beach to Guayaquil in 2025. You can also book with separate airlines for your outbound and return journeys, from $139 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Myrtle Beach to Guayaquil flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Myrtle Beach to Guayaquil airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Myrtle Beach to Guayaquil Flights

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