$183 Cheap Flights from Santiago (STI) to St. Louis (STL)

View $183 flight on Sat, Oct 11, 2025Opens in a new window

Popular airlines from Cibao Intl. Airport (STI) to St. Louis Lambert Intl. Airport (STL)

Cheap Flights from Santiago to St. Louis (STI-STL)

Prices were available within the past 7 days and start at $183 for one-way flights and $597 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Sat, Nov 15 - Sun, Nov 16
STI
Santiago de los Caballeros
STL
St. Louis
$597 Roundtrip, found 5 days ago
$597
Roundtrip
found 5 days ago
Select United flight, departing Sat, Nov 15 from Santiago de los Caballeros to St. Louis, returning Sun, Nov 16, priced at $597 found 5 days ago
Delta
Sat, Nov 15 - Sun, Nov 16
STI
Santiago de los Caballeros
STL
St. Louis
$626 Roundtrip, found 5 days ago
$626
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Nov 15 from Santiago de los Caballeros to St. Louis, returning Sun, Nov 16, priced at $626 found 5 days ago
Delta
Fri, Nov 28 - Sat, Nov 29
STI
Santiago de los Caballeros
STL
St. Louis
$632 Roundtrip, found 5 days ago
$632
Roundtrip
found 5 days ago
Select Delta flight, departing Fri, Nov 28 from Santiago de los Caballeros to St. Louis, returning Sat, Nov 29, priced at $632 found 5 days ago
United
Sat, Nov 15 - Sun, Nov 16
STI
Santiago de los Caballeros
STL
St. Louis
$646 Roundtrip, found 5 days ago
$646
Roundtrip
found 5 days ago
Select United flight, departing Sat, Nov 15 from Santiago de los Caballeros to St. Louis, returning Sun, Nov 16, priced at $646 found 5 days ago
United
Sat, Nov 15 - Sun, Nov 16
STI
Santiago de los Caballeros
STL
St. Louis
$650 Roundtrip, found 5 days ago
$650
Roundtrip
found 5 days ago
Select United flight, departing Sat, Nov 15 from Santiago de los Caballeros to St. Louis, returning Sun, Nov 16, priced at $650 found 5 days ago
United
Mon, Dec 15 - Mon, Dec 29
STI
Santiago de los Caballeros
STL
St. Louis
$657 Roundtrip, found 5 days ago
$657
Roundtrip
found 5 days ago
Select United flight, departing Mon, Dec 15 from Santiago de los Caballeros to St. Louis, returning Mon, Dec 29, priced at $657 found 5 days ago
United
Mon, Dec 15 - Mon, Dec 29
STI
Santiago de los Caballeros
STL
St. Louis
$660 Roundtrip, found 5 days ago
$660
Roundtrip
found 5 days ago
Select United flight, departing Mon, Dec 15 from Santiago de los Caballeros to St. Louis, returning Mon, Dec 29, priced at $660 found 5 days ago
United
Mon, Dec 15 - Mon, Dec 29
STI
Santiago de los Caballeros
STL
St. Louis
$664 Roundtrip, found 5 days ago
$664
Roundtrip
found 5 days ago
Select United flight, departing Mon, Dec 15 from Santiago de los Caballeros to St. Louis, returning Mon, Dec 29, priced at $664 found 5 days ago
United
Mon, Dec 15 - Mon, Dec 29
STI
Santiago de los Caballeros
STL
St. Louis
$666 Roundtrip, found 5 days ago
$666
Roundtrip
found 5 days ago
Select United flight, departing Mon, Dec 15 from Santiago de los Caballeros to St. Louis, returning Mon, Dec 29, priced at $666 found 5 days ago
American Airlines
Sat, Nov 29 - Sat, Dec 13
STI
Santiago de los Caballeros
STL
St. Louis
$852 Roundtrip, found 9 hours ago
$852
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Sat, Nov 29 from Santiago de los Caballeros to St. Louis, returning Sat, Dec 13, priced at $852 found 9 hours ago
Flights from Santiago (STI) to St. Louis (STL)
Origin airport
Cibao Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$597
Distance
1783 mi

Santiago to St. Louis Flights

The cheapest times to fly from Santiago to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santiago to St. Louis are during the month of November. You can find some of the cheapest flights from Santiago to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santiago to St. Louis

Sunday is one of the best days to book for cheap flights from Santiago to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santiago to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santiago to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $183 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santiago to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santiago to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Cibao Intl. Airport (STI) to Lambert-St. Louis Intl. Airport (STL) cost?
Secure a cheap one-way flight from $183 or cheap return flight from $597 from Cibao Intl. Airport (STI) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Cibao Intl. Airport (STI) to Lambert-St. Louis Intl. Airport (STL)?
Traveling in November can help you save, as it's the cheapest month for flights between STI and STL. You'll typically find the lowest fares during off-peak months.
What is the cheapest airline that flies from Cibao Intl. Airport (STI) to Lambert-St. Louis Intl. Airport (STL)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest STI to STL flight.
How many flights per day from Cibao Intl. Airport (STI) to Lambert-St. Louis Intl. Airport (STL)?
You'll have to hop on a flight with a layover if you're traveling from Cibao Intl. Airport (STI) to Lambert-St. Louis Intl. Airport (STL). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to discover an option that works for you.
What day of the week has the most flights from STI to STL?
Friday is usually the busiest day for flights, while Tuesday is often the quietest.* Keep in mind that flight schedules can change depending on a range of factors, such as the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Cibao Intl. Airport (STI) to Lambert-St. Louis Intl. Airport (STL)?
To arrive at Lambert-St. Louis Intl. Airport (STL) without delays, book a flight that leaves Cibao Intl. Airport (STI) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Cibao Intl. Airport (STI) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Booking your plane ticket from STI to STL just before your journey is generally more expensive. But if you're flexible with your travel dates and times, you could score a cheap last-minute fare.
Is it cheaper to book a STI to STL flight and hotel package?
You can save money by securing a STI to STL flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one place. After choosing your ideal accommodations and flights, consider other add-ons like activities, tours and car rentals.
Can I cancel or change the date of my flight from Cibao Intl. Airport (STI) to Lambert-St. Louis Intl. Airport (STL)?
Typically, you're able to cancel or reschedule your STI to STL flight. However, there may be additional charges, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you want more details, visit our Customer Service portal.

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*Available to One Key members.