$224 Cheap Alaska Airlines flights Des Moines (DSM) to San Diego (SAN)

Make use of the “Price (lowest to highest)” filter on Expedia to look for cheap Alaska Airlines return flights from $372 from DSM to SAN. Affordable one-way fares from $224 are available too.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Alaska Airlines flights to San Diego tend to be cheaper in the quieter months of January and November. Whether you’re searching for a one-way or round-trip ticket, you could land a better deal then.

For cheap Alaska Airlines fares from Des Moines Intl. Airport (DSM) to San Diego Intl. Airport (SAN), start searching one to three months before your intended departure. Securing domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also affect the price you pay. Sunday tends to be the most affordable, while Monday is often the most expensive for domestic flights. You can save 6% on average by choosing to book on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Enter your dates, hit search and select the “Nonstop” filter on Expedia to find any direct flights from DSM to SAN with Alaska Airlines or other airlines.

Browse Alaska Airlines’s earliest flights from DSM to SAN by checking the “Early Morning” and “Morning” filters. Not only will you get to your destination sooner, early departures are also 20% less likely to be canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

San Diego Intl. Airport (SAN) is the main San Diego gateway for Alaska Airlines flights from Des Moines Intl. Airport (DSM).

Alaska Airlines makes traveling from DSM to SAN enjoyable with top-tier customer service and a rewarding loyalty program. You may even earn points with Mileage Plan. Don’t forget to join Expedia’s free One Key™ rewards program to earn OneKeyCash™*, which can be redeemed on future bookings.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

It’s generally possible to cancel or reschedule your flight, although additional charges may apply if your booking was made more than 24 hours ago. Need to keep your options open? Use our “Changes included” or “No cancel fee” filter to find flights that won’t charge you extra if you need to alter your plans. To make changes, go to “Trips,” select your flight and click on “Manage Booking” for further information.