$169 Cheap American Airlines flights Denver (DEN) to Guadalajara (GDL)

Landing cheap one-way American Airlines flights from DEN to GDL from $169 on Expedia is simple --- just filter by "Price (lowest to highest)." Alternatively, check out our budget-friendly round-trip fares from $269 for your next exciting getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for American Airlines flights from DEN to GDL about one month before you want to leave. The most affordable time to book an international flight is generally 18 to 29 days ahead of your travel date when you can save 17% versus booking four to five months in advance. Regardless of itinerary or fare class, the best day of the week to book international airfare is usually Sunday. Friday can be the most expensive. Passengers who book on a Sunday can save an average of 17% compared to those who book on a Friday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Filter your results by "Morning" and "Early Morning" to find the earliest flights from DEN to GDL. Jetting off early means you're 20% less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.