$129 Cheap American Airlines flights Des Moines (DSM) to San Jose (SJC)

Landing cheap one-way American Airlines flights from DSM to SJC from $129 on Expedia couldn’t be easier — just filter by “Price (lowest to highest).” Alternatively, check out our budget-friendly round-trip fares from $297 for your next exciting getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for one-way or return flights to San Jose in April or November. You could find a cheap fare with American Airlines during these off-peak months.

Look for cheap American Airlines flights from Des Moines Intl. Airport (DSM) to Norman Y. Mineta San Jose Intl. Airport (SJC) one to three months before your day of departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare type and journey, the best day to book a domestic flight is usually Sunday and the most expensive is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Click on the “Nonstop” filter when looking for direct American Airlines flights from DSM to SJC. It’s also a good way to compare other airlines offering the same direct route.

Find American Airlines’s earliest flights from DSM to SJC by checking the “Early Morning” and “Morning” filters. Not only will you arrive at your destination sooner, early departures are also 20% less likely to be canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Catch an American Airlines flight from Des Moines Intl. Airport (DSM) to San Jose, and you’re most likely to land at Norman Y. Mineta San Jose Intl. Airport (SJC). This is the airline’s main hub in this city.

Changes are typically free within 24 hours of booking, but your airline may charge a fee after that time. For further details about altering your flights, head to your “Trips,” select your flight and click on “Manage Booking.” If you want the flexibility to change your plans without additional charges, tick the “Changes included” or “No cancel fee” filter when planning your next escape.