$109 Cheap American Airlines flights Detroit (DTW) to Memphis (MEM)

You can find budget-friendly return American Airlines flights from $187 from DTW to MEM by organizing your results from "Price (lowest to highest)" on Expedia. Or search for bargains from $109 for a one-way journey.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for affordable American Airlines flights from Detroit Metropolitan Wayne County Airport (DTW) to Memphis Intl. Airport (MEM) one to three months prior to your departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare class and journey, the best day of the week to book a domestic flight is usually Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departure from DTW to MEM with American Airlines, filter your results by "Morning" and "Early Morning." Choosing an early flight generally means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.