$112 Cheap American Airlines flights Milwaukee (MKE) to San Diego (SAN)

Set the “Price (lowest to highest)” filter on Expedia to look for cheap American Airlines return flights from $257 from MKE to SAN. Affordable one-way options from $112 are available too.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

January is one of the cheapest months to travel to San Diego with American Airlines. You could also find excellent prices on return and one-way tickets in November.

Look for cheap American Airlines flights from General Mitchell Intl. Airport (MKE) to San Diego Intl. Airport (SAN) one to three months before your departure day. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare class and itinerary, the best day of the week to book a domestic flight is generally Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Click on the “Nonstop” filter when looking for direct American Airlines flights from MKE to SAN. You’ll also be able to compare other airlines servicing the same direct route.

Sort your results by “Early Morning” and “Morning” to see the earliest flights from MKE to SAN. Taking off early means you’re 20% less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Catch an American Airlines flight from General Mitchell Intl. Airport (MKE) to San Diego, and you’ll likely come in to San Diego Intl. Airport (SAN). This is the airline’s main hub here.

Depending on the ticket type you purchased, a fee typically applies if you cancel or change your booking more than 24 hours after it has been confirmed. To find plane tickets with more flexibility, select our “Changes included” or “No cancel fee” filter when looking for flights. For more information on canceling or modifying your reservation, visit “Trips,” select your flight and tick “Manage Booking.”