$100 Cheap American Airlines flights Washington (DCA) to Key West (EYW)

Scoring cheap one-way American Airlines flights from DCA to EYW from $100 on Expedia couldn't be simpler — just filter by "Price (lowest to highest)." Or check out our budget-friendly return fares from $259 for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Start searching one to three months before your departure to find cheap fares on American Airlines flights from Ronald Reagan Washington National Airport (DCA) to Key West Intl. Airport (EYW). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also reduce costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Get your timing right, and you can enjoy significant savings on domestic journeys.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Taking off from DCA at 7:43AM UTC-5, the earliest American Airlines flight to EYW lands at 11:00AM UTC-5. Traveling earlier in the day means you're less likely to experience cancellations.* Prefer a later start? The last American Airlines flight from DCA to EYW departs at 12:19PM UTC-5 and touches down at 3:30PM UTC-5.*Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.