$384 Cheap Delta flights Panama City (PTY) to San Diego (SAN)

Landing cheap one-way Delta Air Lines flights from PTY to SAN from $384 on Expedia is a breeze --- just filter by "Price (lowest to highest)." Or check out our affordable return fares from $370 for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Getting the best Delta Air Lines deals from PTY to SAN is typically all about timing. You can save 17% on international flights when you book 18 to 29 days before takeoff instead of four to five months ahead. To top it off, you can pocket 17% on average by buying your fare on a Sunday compared to a Friday, which is often the most expensive day to book.* It's smart to kick off your flight search about one month before you want to travel.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Sort your results by "Morning" and "Early Morning" to browse the earliest departures from PTY to SAN. Heading off early means flight cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Heading from PTY to SAN with Delta Air Lines means enjoying a host of perks, including an excellent in-flight experience and a rewarding loyalty program. Plus, when you book through Expedia, One Key™ members can earn OneKeyCash™* to use on select future travel purchases. That's in addition to the Delta SkyMiles points you can earn with Delta Air Lines.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.