$1,756 Cheap Lufthansa flights Lyon (LYS) to San Diego (SAN)

Finding cheap one-way Lufthansa flights from LYS to SAN from $1,756 on Expedia is simple --- just filter by "Price (lowest to highest)." Alternatively, check out our affordable round-trip fares from $730 for your next exciting getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

To find cheap flights from LYS to SAN with Lufthansa, start your search about one month before your planned departure. You can save 17% when you book your international tickets 18 to 29 days ahead instead of booking four to five months in advance. Another tip? Booking on Sunday offers average savings of 17% compared to Friday (the most expensive day).**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Filter your results by "Morning" and "Early Morning" to browse the earliest flights from LYS to SAN. Leaving early means flight cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

With a 5-star airline rating and an excellent in-flight experience, Lufthansa is a top choice for many passengers heading from LYS to SAN. Also, if you're a Lufthansa Miles and More and One Key™ member booking through Expedia, you could earn OneKeyCash™* on eligible flights on top of your airline miles, which can be spent on future travel.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.