$85 Cheap Flights from Cleveland (CLE) to Des Moines (DSM)

View $85 flight on Thu, Nov 6, 2025Opens in a new window

Popular airlines from Cleveland Hopkins International Airport (CLE) to Des Moines International Airport (DSM)

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Cheap Flights from Cleveland to Des Moines (CLE-DSM)

Prices were available within the past 7 days and start at $85 for one-way flights and $170 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Thu, Nov 6 - Mon, Nov 10
CLE
Cleveland
DSM
Des Moines
$170 Roundtrip, found 9 hours ago
$170
Roundtrip
found 9 hours ago
Select Frontier Airlines flight, departing Thu, Nov 6 from Cleveland to Des Moines, returning Mon, Nov 10, priced at $170 found 9 hours ago
Frontier Airlines
Thu, Nov 13 - Sun, Nov 16
CLE
Cleveland
DSM
Des Moines
$201 Roundtrip, found 1 day ago
$201
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Nov 13 from Cleveland to Des Moines, returning Sun, Nov 16, priced at $201 found 1 day ago
American Airlines
Fri, Oct 31 - Mon, Nov 10
CLE
Cleveland
DSM
Des Moines
$204 Roundtrip, found 5 hours ago
$204
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Fri, Oct 31 from Cleveland to Des Moines, returning Mon, Nov 10, priced at $204 found 5 hours ago
Delta
Mon, Nov 10 - Thu, Nov 13
CLE
Cleveland
DSM
Des Moines
$208 Roundtrip, found 18 hours ago
$208
Roundtrip
found 18 hours ago
Select Delta flight, departing Mon, Nov 10 from Cleveland to Des Moines, returning Thu, Nov 13, priced at $208 found 18 hours ago
Southwest Airlines
Tue, Nov 11 - Thu, Nov 13
CLE
Cleveland
DSM
Des Moines
$223 Roundtrip, found 1 day ago
$223
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Tue, Nov 11 from Cleveland to Des Moines, returning Thu, Nov 13, priced at $223 found 1 day ago
Frontier Airlines
Thu, Nov 6 - Thu, Nov 13
CLE
Cleveland
DSM
Des Moines
$227 Roundtrip, found 1 hour ago
$227
Roundtrip
found 1 hour ago
Select Frontier Airlines flight, departing Thu, Nov 6 from Cleveland to Des Moines, returning Thu, Nov 13, priced at $227 found 1 hour ago
American Airlines
Mon, Nov 10 - Thu, Nov 13
CLE
Cleveland
DSM
Des Moines
$233 Roundtrip, found 18 hours ago
$233
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Mon, Nov 10 from Cleveland to Des Moines, returning Thu, Nov 13, priced at $233 found 18 hours ago
Frontier Airlines
Thu, Oct 23 - Mon, Nov 10
CLE
Cleveland
DSM
Des Moines
$234 Roundtrip, found 1 day ago
$234
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Oct 23 from Cleveland to Des Moines, returning Mon, Nov 10, priced at $234 found 1 day ago
American Airlines
Thu, Feb 19 - Sat, Feb 21
CLE
Cleveland
DSM
Des Moines
$237 Roundtrip, found 4 days ago
$237
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Feb 19 from Cleveland to Des Moines, returning Sat, Feb 21, priced at $237 found 4 days ago
United
Fri, Oct 31 - Mon, Nov 10
CLE
Cleveland
DSM
Des Moines
$252 Roundtrip, found 5 hours ago
$252
Roundtrip
found 5 hours ago
Select United flight, departing Fri, Oct 31 from Cleveland to Des Moines, returning Mon, Nov 10, priced at $252 found 5 hours ago

Find the cheapest month to fly from Cleveland (CLE) to Des Moines (DSM)

January is typically the cheapest month to fly

From $129 - $596 per traveler.

Alternative airports near Des Moines

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Des Moines Intl. DSM. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $362
DSM
Des Moines Intl.
CheapestClosest
Average driving time to city center10 min
Flights from $362

Frequently asked questions

How much does a flight from Hopkins Intl. Airport (CLE) to Des Moines Intl. Airport (DSM) cost?
Lock in a cheap one-way flight from $85 or cheap return flight from $170 from Hopkins Intl. Airport (CLE) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Hopkins Intl. Airport (CLE) to Des Moines Intl. Airport (DSM)?
The cheapest month to fly from CLE to DSM is November, when there's less demand. Off-peak months are generally when better flight deals are available between these airports.
What is the cheapest airline that flies from Hopkins Intl. Airport (CLE) to Des Moines Intl. Airport (DSM)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest CLE to DSM flight.
How many flights per day from Hopkins Intl. Airport (CLE) to Des Moines Intl. Airport (DSM)?
Nonstop flights from Hopkins Intl. Airport (CLE) to Des Moines Intl. Airport (DSM) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your travel dates and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from CLE to DSM?
Friday is usually the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can change depending on a number of factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Hopkins Intl. Airport (CLE) to Des Moines Intl. Airport (DSM)?
To touch down at Des Moines Intl. Airport (DSM) on schedule, pick a flight that takes off from Hopkins Intl. Airport (CLE) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Hopkins Intl. Airport (CLE) to Des Moines Intl. Airport (DSM) last-minute?
Booking your flight from CLE to DSM shortly before your getaway is generally more expensive. However, if there's some wiggle room with your travel times and dates, you could land a cheap last-minute fare.
Is it cheaper to book a CLE to DSM flight and hotel package?
Booking a CLE to DSM flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Choose from our impressive range of stays and then add activities, car rentals and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Hopkins Intl. Airport (CLE) to Des Moines Intl. Airport (DSM)?
Typically, you're able to reschedule or cancel your CLE to DSM flight. However, additional fees may apply, especially if you made your booking more than 24 hours ago. Double-check your itinerary for the airline's fees and rules on flight changes, or if you'd like more information, head to our Customer Service portal.

Travel information

Origin airport
Hopkins Intl.
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$170
Distance
610 mi

Book with confidence

Cleveland to Des Moines Flights

The cheapest times to fly from Cleveland to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cleveland to Des Moines are during the month of November. You can find some of the cheapest flights from Cleveland to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cleveland to Des Moines

Sunday is one of the best days to book for cheap flights from Cleveland to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cleveland to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cleveland to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $85 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cleveland to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cleveland to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Cleveland to Des Moines Flights

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*Available to One Key members.