$167 Cheap Flights from Cali (CLO) to Guayaquil (GYE)

View $167 flight on Tue, Nov 11, 2025Opens in a new window

Popular airlines from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Joaquin de Olmedo Intl. Airport (GYE)

Cheap Flights from Cali to Guayaquil (CLO-GYE)

Prices were available within the past 7 days and start at $167 for one-way flights and $272 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Sat, Nov 8 - Tue, Nov 11
CLO
Cali
GYE
Guayaquil
$272 Roundtrip, found 2 days ago
$272
Roundtrip
found 2 days ago
Select Copa flight, departing Sat, Nov 8 from Cali to Guayaquil, returning Tue, Nov 11, priced at $272 found 2 days ago
Copa
Mon, Dec 22 - Thu, Jan 1
CLO
Cali
GYE
Guayaquil
$292 Roundtrip, found 12 hours ago
$292
Roundtrip
found 12 hours ago
Select Copa flight, departing Mon, Dec 22 from Cali to Guayaquil, returning Thu, Jan 1, priced at $292 found 12 hours ago
Copa
Sat, Nov 8 - Tue, Nov 11
CLO
Cali
GYE
Guayaquil
$300 Roundtrip, found 2 days ago
$300
Roundtrip
found 2 days ago
Select Copa flight, departing Sat, Nov 8 from Cali to Guayaquil, returning Tue, Nov 11, priced at $300 found 2 days ago
Copa
Sat, Nov 8 - Wed, Nov 12
CLO
Cali
GYE
Guayaquil
$312 Roundtrip, found 2 days ago
$312
Roundtrip
found 2 days ago
Select Copa flight, departing Sat, Nov 8 from Cali to Guayaquil, returning Wed, Nov 12, priced at $312 found 2 days ago
Copa
Wed, Nov 19 - Mon, Nov 24
CLO
Cali
GYE
Guayaquil
$323 Roundtrip, found 3 days ago
$323
Roundtrip
found 3 days ago
Select Copa flight, departing Wed, Nov 19 from Cali to Guayaquil, returning Mon, Nov 24, priced at $323 found 3 days ago
Copa
Sat, Nov 8 - Wed, Nov 12
CLO
Cali
GYE
Guayaquil
$324 Roundtrip, found 2 days ago
$324
Roundtrip
found 2 days ago
Select Copa flight, departing Sat, Nov 8 from Cali to Guayaquil, returning Wed, Nov 12, priced at $324 found 2 days ago
Copa
Tue, Nov 11 - Wed, Nov 19
CLO
Cali
GYE
Guayaquil
$326 Roundtrip, found 2 days ago
$326
Roundtrip
found 2 days ago
Select Copa flight, departing Tue, Nov 11 from Cali to Guayaquil, returning Wed, Nov 19, priced at $326 found 2 days ago
Copa
Fri, May 1 - Tue, May 5
CLO
Cali
GYE
Guayaquil
$332 Roundtrip, found 3 days ago
$332
Roundtrip
found 3 days ago
Select Copa flight, departing Fri, May 1 from Cali to Guayaquil, returning Tue, May 5, priced at $332 found 3 days ago
Copa
Fri, Nov 7 - Wed, Nov 19
CLO
Cali
GYE
Guayaquil
$336 Roundtrip, found 2 days ago
$336
Roundtrip
found 2 days ago
Select Copa flight, departing Fri, Nov 7 from Cali to Guayaquil, returning Wed, Nov 19, priced at $336 found 2 days ago
LATAM Airlines Group
Wed, Nov 19 - Mon, Nov 24
CLO
Cali
GYE
Guayaquil
$371 Roundtrip, found 3 days ago
$371
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Wed, Nov 19 from Cali to Guayaquil, returning Mon, Nov 24, priced at $371 found 3 days ago

Find the cheapest month to fly from Cali (CLO) to Guayaquil (GYE)

November is typically the cheapest month to fly

From $251 - $466 per traveler.

Alternative airports near Guayaquil

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Jose Joaquin de Olmedo Intl. GYE. Cheapest and Closest option available. Average driving time to city center is 9 minutes. Flights from $487
GYE
Jose Joaquin de Olmedo Intl.
CheapestClosest
Average driving time to city center9 min
Flights from $487
Flights from Cali (CLO) to Guayaquil (GYE)
Origin airport
Alfonso Bonilla Aragon Intl.
Destination airport
Jose Joaquin de Olmedo Intl.
Airlines serving
Copa, LATAM Airlines Group, avianca
Roundtrip price
$272
Distance
461 mi

Cali to Guayaquil Flights

The cheapest times to fly from Cali to Guayaquil

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cali to Guayaquil are during the month of November. You can find some of the cheapest flights from Cali to Guayaquil with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cali to Guayaquil

Sunday is one of the best days to book for cheap flights from Cali to Guayaquil: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cali to Guayaquil

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cali to Guayaquil in 2025. You can also book with separate airlines for your outbound and return journeys, from $167 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cali to Guayaquil flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cali to Guayaquil airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Joaquin de Olmedo Intl. Airport (GYE) cost?
Lock in a cheap one-way flight from $167 or cheap return flight from $272 from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Joaquin de Olmedo Intl. Airport (GYE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
November is the cheapest month to fly from CLO to GYE. Traveling outside of peak seasons is often the key to finding better deals on flights.
What is the cheapest airline that flies from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
Use the filters on Expedia to compare airlines and find the most affordable carrier that'll take you from CLO to GYE. Then, sort your results by "Price (lowest to highest)" to score a good deal.
How many flights per day from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
You'll have to hop on a flight with a layover when traveling from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Joaquin de Olmedo Intl. Airport (GYE). There are no daily direct flights on this route. However, just filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from CLO to GYE?
Friday is usually the busiest day for flights, while Tuesday is often the quietest.* Just remember that flight schedules can change based on a number of factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
To avoid potential delays on the Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Joaquin de Olmedo Intl. Airport (GYE) route, fly before 3 PM. Departures after this hour have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Joaquin de Olmedo Intl. Airport (GYE) last-minute?
Booking your plane ticket from CLO to GYE just before your journey is usually more expensive. But if there's some wiggle room with your schedule, you could grab a cheap last-minute fare.
Is it cheaper to book a CLO to GYE flight and hotel package?
Compared with arranging hotels and flights separately, booking a CLO to GYE flight and hotel package with Expedia could lead to significant savings. What's more, having everything in one easy place will take the stress out of planning your trip. Simply pick your flights and select from our extensive range of stays, then personalize your trip with other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from Alfonso Bonilla Aragon Intl. Airport (CLO) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
If you booked your CLO to GYE flight within the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the fare type you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

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*Available to One Key members.