$128 Cheap Flights from Charlotte (CLT) to Des Moines (DSM)

View $128 flight on Wed, Jan 7, 2026Opens in a new window

Popular airlines from Charlotte-Douglas Intl. Airport (CLT) to Des Moines International Airport (DSM)

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Cheap Flights from Charlotte to Des Moines (CLT-DSM)

Prices were available within the past 7 days and start at $128 for one-way flights and $261 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Thu, Jan 15 - Tue, Jan 20
CLT
Charlotte
DSM
Des Moines
$261 Roundtrip, found 11 hours ago
$261
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Thu, Jan 15 from Charlotte to Des Moines, returning Tue, Jan 20, priced at $261 found 11 hours ago
Frontier Airlines
Thu, Nov 6 - Tue, Nov 11
CLT
Charlotte
DSM
Des Moines
$262 Roundtrip, found 15 hours ago
$262
Roundtrip
found 15 hours ago
Select Frontier Airlines flight, departing Thu, Nov 6 from Charlotte to Des Moines, returning Tue, Nov 11, priced at $262 found 15 hours ago
Southwest Airlines
Thu, Jan 15 - Tue, Jan 20
CLT
Charlotte
DSM
Des Moines
$289 Roundtrip, found 11 hours ago
$289
Roundtrip
found 11 hours ago
Select Southwest Airlines flight, departing Thu, Jan 15 from Charlotte to Des Moines, returning Tue, Jan 20, priced at $289 found 11 hours ago
Frontier Airlines
Thu, Nov 6 - Tue, Nov 11
CLT
Charlotte
DSM
Des Moines
$291 Roundtrip, found 15 hours ago
$291
Roundtrip
found 15 hours ago
Select Frontier Airlines flight, departing Thu, Nov 6 from Charlotte to Des Moines, returning Tue, Nov 11, priced at $291 found 15 hours ago
Southwest Airlines
Thu, Jan 15 - Tue, Jan 20
CLT
Charlotte
DSM
Des Moines
$295 Roundtrip, found 11 hours ago
$295
Roundtrip
found 11 hours ago
Select Southwest Airlines flight, departing Thu, Jan 15 from Charlotte to Des Moines, returning Tue, Jan 20, priced at $295 found 11 hours ago
Frontier Airlines
Mon, Dec 22 - Wed, Jan 7
CLT
Charlotte
DSM
Des Moines
$303 Roundtrip, found 2 days ago
$303
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Mon, Dec 22 from Charlotte to Des Moines, returning Wed, Jan 7, priced at $303 found 2 days ago
American Airlines
Thu, Jan 15 - Tue, Jan 20
CLT
Charlotte
DSM
Des Moines
$305 Roundtrip, found 11 hours ago
$305
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Thu, Jan 15 from Charlotte to Des Moines, returning Tue, Jan 20, priced at $305 found 11 hours ago
Southwest Airlines
Thu, Jan 15 - Tue, Jan 20
CLT
Charlotte
DSM
Des Moines
$309 Roundtrip, found 11 hours ago
$309
Roundtrip
found 11 hours ago
Select Southwest Airlines flight, departing Thu, Jan 15 from Charlotte to Des Moines, returning Tue, Jan 20, priced at $309 found 11 hours ago
Delta
Sat, Jan 3 - Tue, Jan 6
CLT
Charlotte
DSM
Des Moines
$393 Roundtrip, found 1 day ago
$393
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Jan 3 from Charlotte to Des Moines, returning Tue, Jan 6, priced at $393 found 1 day ago
United
Tue, Dec 30 - Sat, Jan 3
CLT
Charlotte
DSM
Des Moines
$393 Roundtrip, found 4 days ago
$393
Roundtrip
found 4 days ago
Select United flight, departing Tue, Dec 30 from Charlotte to Des Moines, returning Sat, Jan 3, priced at $393 found 4 days ago

Find the cheapest month to fly from Charlotte (CLT) to Des Moines (DSM)

March is typically the cheapest month to fly

From $170 - $567 per traveler.

Alternative airports near Des Moines

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Des Moines Intl. DSM. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $520
DSM
Des Moines Intl.
CheapestClosest
Average driving time to city center10 min
Flights from $520

Frequently asked questions

How much does a flight from Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM) cost?
Grab a cheap one-way flight from $128 or cheap return flight from $261 from Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM)?
Planning your getaway for January is a good way to save, as it's the cheapest month for flights between CLT and DSM. You'll often find the lowest prices during off-peak months.
Which airlines fly direct from Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM)?
If you're departing from Charlotte-Douglas Intl. Airport (CLT), you can board a direct flight to Des Moines Intl. Airport (DSM) with American Airlines.
What is the cheapest airline that flies from Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM)?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll fly you from CLT to DSM. Then, sort your results by "Price (lowest to highest)" to score the best deal available.
How many flights per day from Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM)?
Each day, an average of 2 nonstop flights take off from Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM). Choose the departure date that best suits your travel plans.
What are the most popular departure times for flights from Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM)?
The 12 PM departures from CLT to DSM are typically the busiest. These flights can come with a higher price due to their popularity. If you want to save on your fare, book during off-peak hours.
What day of the week has the most flights from CLT to DSM?
Depart on a Monday if you're searching for the best selection of flights from Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM).
What is the earliest flight from Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM)?
Hop on the earliest flight at around 12:06PM UTC-5, departing from Charlotte-Douglas Intl. Airport (CLT). You'll be in the air for about 2h 30m, coming in to land at Des Moines Intl. Airport (DSM) at approximately 1:36PM UTC-6.
How long does it take to fly from Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM)?
It takes approximately 2 hours and 32 minutes to cover the 810 mi from CLT to DSM.
What airline has the least delays from CLT to DSM?
With 80% of journeys typically landing on time, American Airlines has the best on-time performance for nonstop flights from Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM). To monitor your flight status and receive notifications if anything changes, simply head to the Expedia App.
What is the best time to fly from Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM)?
To touch down at Des Moines Intl. Airport (DSM) on schedule, book a flight that leaves from Charlotte-Douglas Intl. Airport (CLT) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Des Moines from Charlotte-Douglas Intl. Airport (CLT)?
If you're on a direct flight from Charlotte-Douglas Intl. Airport (CLT) to Des Moines, Des Moines Intl. Airport (DSM) is the only airport you can touch down at.
Is it cheaper to buy a plane ticket from Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM) last-minute?
Holding off until just before your departure to book a flight from CLT to DSM often results in higher prices. While you might find some last-minute offers, they're not always guaranteed. Be flexible with your travel plans to maximize your chances of snagging a bargain.
Is it cheaper to book a CLT to DSM flight and hotel package?
Opting for a CLT to DSM flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Pick from our impressive range of stays and then add car rentals, activities and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Charlotte-Douglas Intl. Airport (CLT) to Des Moines Intl. Airport (DSM)?
If you booked your CLT to DSM flight within the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the fare type you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Charlotte-Douglas Intl.
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$261
Distance
813 mi
Average flight time
1 hour 40 mins

Book with confidence

Charlotte to Des Moines Flights

The cheapest times to fly from Charlotte to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charlotte to Des Moines are during the month of January. You can find some of the cheapest flights from Charlotte to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Charlotte to Des Moines

Sunday is one of the best days to book for cheap flights from Charlotte to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Charlotte to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charlotte to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $128 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charlotte to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Charlotte to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Charlotte to Des Moines Flights

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*Available to One Key members.