$64 Cheap Flights from Denver (DEN) to Des Moines (DSM)

View $64 flight on Wed, Oct 8, 2025Opens in a new window

Popular airlines from Denver Intl. Airport (DEN) to Des Moines International Airport (DSM)

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Cheap Flights from Denver to Des Moines (DEN-DSM)

Prices were available within the past 7 days and start at $64 for one-way flights and $108 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Wed, Oct 8 - Wed, Oct 15
DEN
Denver
DSM
Des Moines
$108 Roundtrip, found 3 days ago
$108
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Wed, Oct 8 from Denver to Des Moines, returning Wed, Oct 15, priced at $108 found 3 days ago
Frontier Airlines
Wed, Oct 15 - Wed, Oct 22
DEN
Denver
DSM
Des Moines
$118 Roundtrip, found 7 hours ago
$118
Roundtrip
found 7 hours ago
Select Frontier Airlines flight, departing Wed, Oct 15 from Denver to Des Moines, returning Wed, Oct 22, priced at $118 found 7 hours ago
Frontier Airlines
Thu, Sep 11 - Thu, Sep 18
DEN
Denver
DSM
Des Moines
$120 Roundtrip, just found
$120
Roundtrip
just found
Select Frontier Airlines flight, departing Thu, Sep 11 from Denver to Des Moines, returning Thu, Sep 18, priced at $120 just found
Frontier Airlines
Wed, Oct 22 - Sun, Oct 26
DEN
Denver
DSM
Des Moines
$123 Roundtrip, found 6 days ago
$123
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Wed, Oct 22 from Denver to Des Moines, returning Sun, Oct 26, priced at $123 found 6 days ago
Frontier Airlines
Wed, Oct 8 - Mon, Oct 13
DEN
Denver
DSM
Des Moines
$123 Roundtrip, found 14 hours ago
$123
Roundtrip
found 14 hours ago
Select Frontier Airlines flight, departing Wed, Oct 8 from Denver to Des Moines, returning Mon, Oct 13, priced at $123 found 14 hours ago
Frontier Airlines
Fri, Sep 5 - Mon, Sep 8
DEN
Denver
DSM
Des Moines
$126 Roundtrip, found 2 days ago
$126
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Fri, Sep 5 from Denver to Des Moines, returning Mon, Sep 8, priced at $126 found 2 days ago
United
Sat, Aug 9 - Wed, Aug 13
DEN
Denver
DSM
Des Moines
$127 Roundtrip, found 4 days ago
$127
Roundtrip
found 4 days ago
Select United flight, departing Sat, Aug 9 from Denver to Des Moines, returning Wed, Aug 13, priced at $127 found 4 days ago
Southwest Airlines
Thu, Sep 11 - Sat, Sep 13
DEN
Denver
DSM
Des Moines
$131 Roundtrip, found 4 days ago
$131
Roundtrip
found 4 days ago
Select Southwest Airlines flight, departing Thu, Sep 11 from Denver to Des Moines, returning Sat, Sep 13, priced at $131 found 4 days ago
American Airlines
Sat, Oct 18 - Sat, Oct 25
DEN
Denver
DSM
Des Moines
$139 Roundtrip, found 6 days ago
$139
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sat, Oct 18 from Denver to Des Moines, returning Sat, Oct 25, priced at $139 found 6 days ago
Delta
Fri, Oct 10 - Tue, Oct 14
DEN
Denver
DSM
Des Moines
$207 Roundtrip, just found
$207
Roundtrip
just found
Select Delta flight, departing Fri, Oct 10 from Denver to Des Moines, returning Tue, Oct 14, priced at $207 just found

Find the cheapest month to fly from Denver (DEN) to Des Moines (DSM)

August is typically the cheapest month to fly

From $53 - $237 per traveler.

Graph displaying average flight prices per month

Flights from Denver (DEN) to Des Moines (DSM)
Origin airport
Denver Intl.
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$108
Distance
588 mi
Average flight time
2 hours 48 mins

Denver to Des Moines Flights

The cheapest times to fly from Denver to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Denver to Des Moines are during the month of October. You can find some of the cheapest flights from Denver to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Denver to Des Moines

Sunday is one of the best days to book for cheap flights from Denver to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Denver to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Denver to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $64 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Denver to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Denver to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM) cost?
Cheap return flights from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM) start at $108. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Frontier Airlines flight leaving DEN on August 9 2025 and touching down at DSM. The price was last updated on July 13 2025 and has not changed since.
What is the cheapest month to fly from DEN to DSM?
The cheapest flights from DEN to DSM are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM)?
You can fly nonstop from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM) on a United Airlines flight.
What is the cheapest airline that flies from DEN to DSM?
Currently, the cheapest carrier operating one-way flights from DEN to DSM is Southwest Airlines. You can take off on this route from $59. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from DEN on October 8 2025. Prices were last updated on July 13 2025 and have not changed since.
How many flights per day from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM)?
With an average of 5 direct flights that operate from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM) each day, you'll be jetting off in no time.
What are the most popular departure times for flights from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM)?
More travelers fly between DEN and DSM at 5 PM than at any other point in the day. Looking to skip the crowds? Pick a flight outside the busiest times and you could save on your fare as well.
What day of the week has the most flights from DEN to DSM?
If you jet off on a Monday, you'll get the largest range of choices for flights from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM).
What is the earliest flight from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM)?
The first flight of the day jetting off from Denver Intl. Airport (DEN) is at around 9:55AM UTC-7. Hop on this flight and you'll touch down at Des Moines Intl. Airport (DSM) at approximately 12:55PM UTC-6. The total time in the air is 2h.
How long does it take to fly from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM)?
Flights from DEN to DSM have an average travel time of 1 hour and 50 minutes. The distance between the two is 590 mi.
What is the best time to fly from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM)?
Opt for a flight from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM) that takes off before 3 PM to reduce the risk of cancellations. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Des Moines from Denver Intl. Airport (DEN)?
If you're on a direct flight from Denver Intl. Airport (DEN) to Des Moines, Des Moines Intl. Airport (DSM) is the only airport you can touch down at.
Is it cheaper to buy a plane ticket from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM) last-minute?
Last-minute fares from DEN to DSM are generally more expensive. For the cheapest rates, start searching for flights well ahead of time. That said, if you can play around with your travel dates, you may find a cheap fare right before your journey.
Is it cheaper to book a DEN to DSM flight and hotel package?
Opting for a DEN to DSM flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip in one place. Select from our impressive range of accommodations and then add car rentals, activities and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM)?
If you reserved your DEN to DSM flight in the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the fare type you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more details.

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*Available to One Key members.