Cheap Flights from Destin (DSI) to Panama City (PTY)

Popular airlines from Destin-Fort Walton Beach Airport (DSI) to Tocumen Intl. Airport (PTY)

Frequently asked questions

How much does a flight from Destin-Fort Walton Beach Airport (DSI) to Tocumen Intl. Airport (PTY) cost?
Secure a cheap one-way flight or cheap return flight from Destin-Fort Walton Beach Airport (DSI) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Destin-Fort Walton Beach Airport (DSI) to Tocumen Intl. Airport (PTY)?
The cheapest month to fly from DSI to PTY is , when demand is low. Off-peak season is generally when airlines offer better prices between these airports.
What is the cheapest airline that flies from Destin-Fort Walton Beach Airport (DSI) to Tocumen Intl. Airport (PTY)?
Use the filters on Expedia to compare different airlines and find the cheapest carrier that'll fly you from DSI to PTY. Then, sort your results by "Price (lowest to highest)" to snag a great deal.
How many flights per day from Destin-Fort Walton Beach Airport (DSI) to Tocumen Intl. Airport (PTY)?
There aren't any daily nonstop flights available from Destin-Fort Walton Beach Airport (DSI) to Tocumen Intl. Airport (PTY). But you can choose flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be cruising above the clouds in no time at all.
What day of the week has the most flights from DSI to PTY?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary based on a number of factors, such as the season and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Destin-Fort Walton Beach Airport (DSI) to Tocumen Intl. Airport (PTY)?
To avoid possible delays on the Destin-Fort Walton Beach Airport (DSI) to Tocumen Intl. Airport (PTY) route, travel before 3 PM. Flights after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Destin-Fort Walton Beach Airport (DSI) to Tocumen Intl. Airport (PTY) last-minute?
Booking your ticket from DSI to PTY right before your getaway is typically more expensive. However, if there's some wiggle room with your travel times and dates, you could bag a cheap last-minute fare.
Is it cheaper to book a DSI to PTY flight and hotel package?
You can save money by securing a DSI to PTY flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one convenient place. Once you've chosen your preferred flights and accommodations, consider adding extras such as car rentals, activities and tours.
Can I cancel or change the date of my flight from Destin-Fort Walton Beach Airport (DSI) to Tocumen Intl. Airport (PTY)?
Typically, you're able to cancel or reschedule your DSI to PTY flight. However, there may be additional charges, especially if you booked more than 24 hours ago. Check your itinerary for the airline's guidelines and fees on flight changes, or if you'd like more information, go to our Customer Service portal.

Travel information

Origin airport
Destin-Fort Walton Beach
Destination airport
Tocumen Intl.
Distance
1542 mi

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Destin to Panama City Flights

The cheapest times to fly from Destin to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Destin to Panama City are during the month of . You can find some of the cheapest flights from Destin to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Destin to Panama City

Sunday is one of the best days to book for cheap flights from Destin to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Destin to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Destin to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Destin to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Destin to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Destin to Panama City Flights

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*Available to One Key members.