$329 Cheap Flights from Guadalajara (GDL) to Santiago (SCL)

View $329 flight on Mon, Jan 12, 2026Opens in a new window

Popular airlines from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Santiago Intl. Airport (SCL)

Cheap Flights from Guadalajara to Santiago (GDL-SCL)

Prices were available within the past 7 days and start at $329 for one-way flights and $632 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Thu, Oct 30 - Wed, Nov 12
GDL
Guadalajara
SCL
Santiago
$632 Roundtrip, found 19 hours ago
$632
Roundtrip
found 19 hours ago
Select Aeromexico flight, departing Thu, Oct 30 from Guadalajara to Santiago, returning Wed, Nov 12, priced at $632 found 19 hours ago
Aeromexico
Wed, Feb 18 - Mon, Feb 23
GDL
Guadalajara
SCL
Santiago
$637 Roundtrip, found 1 day ago
$637
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Wed, Feb 18 from Guadalajara to Santiago, returning Mon, Feb 23, priced at $637 found 1 day ago
Aeromexico
Thu, Nov 27 - Sat, Dec 6
GDL
Guadalajara
SCL
Santiago
$642 Roundtrip, found 6 days ago
$642
Roundtrip
found 6 days ago
Select Aeromexico flight, departing Thu, Nov 27 from Guadalajara to Santiago, returning Sat, Dec 6, priced at $642 found 6 days ago
Aeromexico
Thu, Nov 27 - Sat, Dec 6
GDL
Guadalajara
SCL
Santiago
$646 Roundtrip, found 6 days ago
$646
Roundtrip
found 6 days ago
Select Aeromexico flight, departing Thu, Nov 27 from Guadalajara to Santiago, returning Sat, Dec 6, priced at $646 found 6 days ago
Copa
Fri, Nov 28 - Thu, Dec 11
GDL
Guadalajara
SCL
Santiago
$660 Roundtrip, found 2 days ago
$660
Roundtrip
found 2 days ago
Select Copa flight, departing Fri, Nov 28 from Guadalajara to Santiago, returning Thu, Dec 11, priced at $660 found 2 days ago
Copa
Sat, Oct 25 - Wed, Oct 29
GDL
Guadalajara
SCL
Santiago
$681 Roundtrip, found 2 days ago
$681
Roundtrip
found 2 days ago
Select Copa flight, departing Sat, Oct 25 from Guadalajara to Santiago, returning Wed, Oct 29, priced at $681 found 2 days ago
Aeromexico
Thu, Nov 6 - Mon, Nov 10
GDL
Guadalajara
SCL
Santiago
$684 Roundtrip, found 3 days ago
$684
Roundtrip
found 3 days ago
Select Aeromexico flight, departing Thu, Nov 6 from Guadalajara to Santiago, returning Mon, Nov 10, priced at $684 found 3 days ago
United
Mon, Dec 1 - Wed, Dec 10
GDL
Guadalajara
SCL
Santiago
$1,353 Roundtrip, found 2 days ago
$1,353
Roundtrip
found 2 days ago
Select United flight, departing Mon, Dec 1 from Guadalajara to Santiago, returning Wed, Dec 10, priced at $1,353 found 2 days ago
American Airlines
Mon, Dec 1 - Wed, Dec 10
GDL
Guadalajara
SCL
Santiago
$1,703 Roundtrip, found 2 days ago
$1,703
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Dec 1 from Guadalajara to Santiago, returning Wed, Dec 10, priced at $1,703 found 2 days ago
Delta
Sun, Dec 21 - Mon, Dec 22
GDL
Guadalajara
SCL
Santiago
$2,655 Roundtrip, found 14 hours ago
$2,655
Roundtrip
found 14 hours ago
Select Delta flight, departing Sun, Dec 21 from Guadalajara to Santiago, returning Mon, Dec 22, priced at $2,655 found 14 hours ago

Find the cheapest month to fly from Guadalajara (GDL) to Santiago (SCL)

August is typically the cheapest month to fly

From $485 - $1,223 per traveler.

Alternative airports near Santiago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Arturo Merino Benitez SCL. Cheapest and Closest option available. Average driving time to city center is 17 minutes. Flights from $684
SCL
Arturo Merino Benitez
CheapestClosest
Average driving time to city center17 min
Flights from $684
Flights from Guadalajara (GDL) to Santiago (SCL)
Origin airport
Don Miguel Hidalgo y Costilla Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Aeromexico, American Airlines, Copa, Delta, United
Roundtrip price
$632
Distance
4297 mi

Guadalajara to Santiago Flights

The cheapest times to fly from Guadalajara to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Guadalajara to Santiago are during the month of October. You can find some of the cheapest flights from Guadalajara to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Guadalajara to Santiago

Sunday is one of the best days to book for cheap flights from Guadalajara to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Guadalajara to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Guadalajara to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $329 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Guadalajara to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Guadalajara to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Arturo Merino Benitez Airport (SCL) cost?
Secure a cheap one-way flight from $329 or cheap return flight from $632 from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Arturo Merino Benitez Airport (SCL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Arturo Merino Benitez Airport (SCL)?
The cheapest month to fly from GDL to SCL is October, when demand is low. Off-peak months are typically when you'll find cheap fares for travel between these airports.
What is the cheapest airline that flies from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Arturo Merino Benitez Airport (SCL)?
To find the cheapest airline that'll fly you from GDL to SCL, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Arturo Merino Benitez Airport (SCL)?
There are no daily direct flights departing from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Arturo Merino Benitez Airport (SCL). But you can opt for flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be cruising above the clouds before you know it.
What day of the week has the most flights from GDL to SCL?
Typically you'll find the greatest selection of flight options on a Friday. Tuesdays tend to be the quietest.* But this can change based on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Arturo Merino Benitez Airport (SCL)?
To reach Arturo Merino Benitez Airport (SCL) on time, opt for a flight that leaves Don Miguel Hidalgo y Costilla Intl. Airport (GDL) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Arturo Merino Benitez Airport (SCL) last-minute?
Booking your ticket from GDL to SCL right before your trip is typically more expensive. However, if there's some wiggle room with your schedule, you could grab a cheap last-minute fare.
Is it cheaper to book a GDL to SCL flight and hotel package?
Booking a GDL to SCL flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Pick from our extensive range of hotels and then add activities, car rentals and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Arturo Merino Benitez Airport (SCL)?
If you booked your GDL to SCL flight within the last 24 hours, you may be able to modify or cancel it without fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for more information.

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*Available to One Key members.