$515 Cheap Flights from Lyon (LYS) to San Francisco (SFO)

View $515 flight on Tue, May 19, 2026Opens in a new window

Popular airlines from Saint-Exupery Airport (LYS) to San Francisco Intl. Airport (SFO)

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Cheap Flights from Lyon to San Francisco (LYS-SFO)

Prices were available within the past 7 days and start at $515 for one-way flights and $519 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

TAP Portugal
Thu, Nov 20 - Fri, Nov 28
LYS
Lyon
SFO
San Francisco
$519 Roundtrip, found 2 days ago
$519
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Thu, Nov 20 from Lyon to San Francisco, returning Fri, Nov 28, priced at $519 found 2 days ago
TAP Portugal
Mon, Feb 2 - Mon, Feb 23
LYS
Lyon
SFO
San Francisco
$522 Roundtrip, found 6 hours ago
$522
Roundtrip
found 6 hours ago
Select TAP Portugal flight, departing Mon, Feb 2 from Lyon to San Francisco, returning Mon, Feb 23, priced at $522 found 6 hours ago
TAP Portugal
Mon, Feb 2 - Wed, Feb 25
LYS
Lyon
SFO
San Francisco
$526 Roundtrip, found 6 hours ago
$526
Roundtrip
found 6 hours ago
Select TAP Portugal flight, departing Mon, Feb 2 from Lyon to San Francisco, returning Wed, Feb 25, priced at $526 found 6 hours ago
Air Canada
Thu, Nov 20 - Fri, Nov 28
LYS
Lyon
SFO
San Francisco
$544 Roundtrip, found 2 days ago
$544
Roundtrip
found 2 days ago
Select Air Canada flight, departing Thu, Nov 20 from Lyon to San Francisco, returning Fri, Nov 28, priced at $544 found 2 days ago
Lufthansa
Tue, Apr 7 - Wed, Apr 15
LYS
Lyon
SFO
San Francisco
$546 Roundtrip, found 6 days ago
$546
Roundtrip
found 6 days ago
Select Lufthansa flight, departing Tue, Apr 7 from Lyon to San Francisco, returning Wed, Apr 15, priced at $546 found 6 days ago
Air Canada
Thu, Dec 4 - Wed, Feb 4
LYS
Lyon
SFO
San Francisco
$547 Roundtrip, found 1 day ago
$547
Roundtrip
found 1 day ago
Select Air Canada flight, departing Thu, Dec 4 from Lyon to San Francisco, returning Wed, Feb 4, priced at $547 found 1 day ago
Lufthansa
Fri, Nov 14 - Tue, Dec 2
LYS
Lyon
SFO
San Francisco
$552 Roundtrip, found 6 days ago
$552
Roundtrip
found 6 days ago
Select Lufthansa flight, departing Fri, Nov 14 from Lyon to San Francisco, returning Tue, Dec 2, priced at $552 found 6 days ago
British Airways
Sun, Jan 18 - Tue, Mar 17
LYS
Lyon
SFO
San Francisco
$553 Roundtrip, found 4 days ago
$553
Roundtrip
found 4 days ago
Select British Airways flight, departing Sun, Jan 18 from Lyon to San Francisco, returning Tue, Mar 17, priced at $553 found 4 days ago
Brussels Airlines
Tue, Apr 7 - Wed, Apr 15
LYS
Lyon
SFO
San Francisco
$586 Roundtrip, found 6 days ago
$586
Roundtrip
found 6 days ago
Select Brussels Airlines flight, departing Tue, Apr 7 from Lyon to San Francisco, returning Wed, Apr 15, priced at $586 found 6 days ago
Scandinavian Airlines
Sat, Jan 17 - Sat, Jan 31
LYS
Lyon
SFO
San Francisco
$667 Roundtrip, found 1 day ago
$667
Roundtrip
found 1 day ago
Select Scandinavian Airlines flight, departing Sat, Jan 17 from Lyon to San Francisco, returning Sat, Jan 31, priced at $667 found 1 day ago

Alternative airports near San Francisco

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Norman Y. Mineta San Jose Intl. SJC. Cheapest option available. Average driving time to city center is 50 minutes. Flights from $862
SJC
Norman Y. Mineta San Jose Intl.
Cheapest
Average driving time to city center50 min
Flights from $862

Frequently asked questions

How much does a flight from Saint-Exupery Airport (LYS) to San Francisco Intl. Airport (SFO) cost?
Snag a cheap one-way flight from $515 or cheap return flight from $519 from Saint-Exupery Airport (LYS) to San Francisco Intl. Airport (SFO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Saint-Exupery Airport (LYS) to San Francisco Intl. Airport (SFO)?
November is the cheapest month to fly from LYS to SFO. Traveling outside of peak seasons is often the key to better flight prices.
What is the cheapest airline that flies from Saint-Exupery Airport (LYS) to San Francisco Intl. Airport (SFO)?
Use the filters on Expedia to compare airlines and find the most affordable carrier that'll fly you from LYS to SFO. Then, sort your results by "Price (lowest to highest)" to pick up the best deal available.
How many flights per day from Saint-Exupery Airport (LYS) to San Francisco Intl. Airport (SFO)?
You'll have to book a flight with a layover if you're traveling from Saint-Exupery Airport (LYS) to San Francisco Intl. Airport (SFO). There are no daily direct flights on this route. However, just filter your search to include one or more stops to find an option that works for you.
What day of the week has the most flights from LYS to SFO?
Generally you'll have the most choice when it comes to flights on a Friday. Tuesdays are often the quietest.* But this can change based on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Saint-Exupery Airport (LYS) to San Francisco Intl. Airport (SFO)?
To avoid possible delays on the Saint-Exupery Airport (LYS) to San Francisco Intl. Airport (SFO) route, travel before 3 PM. Later flights are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Saint-Exupery Airport (LYS) to San Francisco Intl. Airport (SFO) last-minute?
Holding off until just before your trip to book a ticket from LYS to SFO generally means paying more. While you might find some last-minute offers, they're not always guaranteed. Keep your travel schedule open for a better chance of scoring a bargain.
Is it cheaper to book a LYS to SFO flight and hotel package?
You can save money by securing a LYS to SFO flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. Once you've chosen your preferred flights and accommodations, you can add extras such as activities, car rentals and tours.
Can I cancel or change the date of my flight from Saint-Exupery Airport (LYS) to San Francisco Intl. Airport (SFO)?
If you booked your LYS to SFO flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of fare you have, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more information.

Travel information

Origin airport
Saint-Exupery
Destination airport
San Francisco Intl.
Airlines serving
Aer Lingus, Air Canada, Air France, American Airlines, Austrian Airlines, British Airways, Brussels Airlines, Delta, Iberia, KLM, Lufthansa, Scandinavian Airlines, TAP Portugal, Turkish Airlines, United
Roundtrip price
$518
Distance
5819 mi

Book with confidence

Lyon to San Francisco Flights

The cheapest times to fly from Lyon to San Francisco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Lyon to San Francisco are during the month of November. You can find some of the cheapest flights from Lyon to San Francisco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Lyon to San Francisco

Sunday is one of the best days to book for cheap flights from Lyon to San Francisco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Lyon to San Francisco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Lyon to San Francisco in 2025. You can also book with separate airlines for your outbound and return journeys, from $515 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Lyon to San Francisco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Lyon to San Francisco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Lyon to San Francisco Flights

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*Available to One Key members.