$119 Cheap Flights from Manchester (MHT) to St. Louis (STL)

View $119 flight on Wed, Aug 27, 2025Opens in a new window

Popular airlines from Manchester-Boston Regional Airport (MHT) to St. Louis Lambert Intl. Airport (STL)

Cheap Flights from Manchester to St. Louis (MHT-STL)

Prices were available within the past 7 days and start at $119 for one-way flights and $237 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Sep 2 - Tue, Sep 16
MHT
Manchester
STL
St. Louis
$237 Roundtrip, found 17 hours ago
$237
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Tue, Sep 2 from Manchester to St. Louis, returning Tue, Sep 16, priced at $237 found 17 hours ago
Southwest Airlines
Tue, Sep 2 - Tue, Sep 16
MHT
Manchester
STL
St. Louis
$237 Roundtrip, found 17 hours ago
$237
Roundtrip
found 17 hours ago
Select Southwest Airlines flight, departing Tue, Sep 2 from Manchester to St. Louis, returning Tue, Sep 16, priced at $237 found 17 hours ago
United
Wed, Sep 24 - Tue, Sep 30
MHT
Manchester
STL
St. Louis
$242 Roundtrip, found 4 days ago
$242
Roundtrip
found 4 days ago
Select United flight, departing Wed, Sep 24 from Manchester to St. Louis, returning Tue, Sep 30, priced at $242 found 4 days ago
American Airlines
Thu, Aug 28 - Sun, Aug 31
MHT
Manchester
STL
St. Louis
$252 Roundtrip, found 20 hours ago
$252
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Thu, Aug 28 from Manchester to St. Louis, returning Sun, Aug 31, priced at $252 found 20 hours ago
Southwest Airlines
Fri, Oct 3 - Mon, Oct 6
MHT
Manchester
STL
St. Louis
$259 Roundtrip, found 17 hours ago
$259
Roundtrip
found 17 hours ago
Select Southwest Airlines flight, departing Fri, Oct 3 from Manchester to St. Louis, returning Mon, Oct 6, priced at $259 found 17 hours ago
American Airlines
Thu, Sep 18 - Tue, Sep 23
MHT
Manchester
STL
St. Louis
$263 Roundtrip, found 2 days ago
$263
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Sep 18 from Manchester to St. Louis, returning Tue, Sep 23, priced at $263 found 2 days ago
Southwest Airlines
Tue, Sep 2 - Tue, Sep 16
MHT
Manchester
STL
St. Louis
$264 Roundtrip, found 17 hours ago
$264
Roundtrip
found 17 hours ago
Select Southwest Airlines flight, departing Tue, Sep 2 from Manchester to St. Louis, returning Tue, Sep 16, priced at $264 found 17 hours ago
American Airlines
Thu, Aug 28 - Mon, Sep 1
MHT
Manchester
STL
St. Louis
$267 Roundtrip, found 20 hours ago
$267
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Thu, Aug 28 from Manchester to St. Louis, returning Mon, Sep 1, priced at $267 found 20 hours ago
American Airlines
Thu, Aug 21 - Wed, Aug 27
MHT
Manchester
STL
St. Louis
$268 Roundtrip, found 4 days ago
$268
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Aug 21 from Manchester to St. Louis, returning Wed, Aug 27, priced at $268 found 4 days ago
American Airlines
Thu, Aug 28 - Mon, Sep 1
MHT
Manchester
STL
St. Louis
$273 Roundtrip, found 20 hours ago
$273
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Thu, Aug 28 from Manchester to St. Louis, returning Mon, Sep 1, priced at $273 found 20 hours ago

Find the cheapest month to fly from Manchester (MHT) to St. Louis (STL)

August is typically the cheapest month to fly

From $179 - $752 per traveler.

Graph displaying average flight prices per month

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $422
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $422
Flights from Manchester (MHT) to St. Louis (STL)
Origin airport
Manchester-Boston Regional
Destination airport
Lambert-St. Louis Intl.
Airlines serving
American Airlines, Southwest Airlines, United
Roundtrip price
$236
Distance
1028 mi

Manchester to St. Louis Flights

The cheapest times to fly from Manchester to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Manchester to St. Louis are during the month of September. You can find some of the cheapest flights from Manchester to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Manchester to St. Louis

Sunday is one of the best days to book for cheap flights from Manchester to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Manchester to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Manchester to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $119 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Manchester to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Manchester to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Manchester-Boston Regional Airport (MHT) to Lambert-St. Louis Intl. Airport (STL) cost?
Discover the latest flight deals from MHT to STL by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from MHT to STL?
The cheapest flights from MHT to STL are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Manchester-Boston Regional Airport (MHT) to Lambert-St. Louis Intl. Airport (STL)?
You can't fly directly from Manchester, NH (MHT-Manchester-Boston Regional) to Lambert-St. Louis Intl. Airport (STL). However, there are other airports offering nonstop flights. Begin your journey at Logan Intl. Airport (BOS) and head straight to St. Louis without any detours.
What is the cheapest airline that flies from MHT to STL?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from MHT to STL. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Manchester-Boston Regional Airport (MHT) to Lambert-St. Louis Intl. Airport (STL)?
Nonstop flights from Manchester-Boston Regional Airport (MHT) to Lambert-St. Louis Intl. Airport (STL) aren't available daily, so you'll have to take a flight with a layover. Explore your options with our filter tool. Enter your travel details and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MHT to STL?
Generally you'll have the most choice when it comes to flights on a Friday. Tuesdays are often the quietest.* But this can vary depending on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Manchester-Boston Regional Airport (MHT) to Lambert-St. Louis Intl. Airport (STL)?
To avoid possible delays on the Manchester-Boston Regional Airport (MHT) to Lambert-St. Louis Intl. Airport (STL) route, travel before 3 PM. Later departures have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Manchester-Boston Regional Airport (MHT) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Holding off until just before your departure to book your flight from MHT to STL generally means paying more. While you may find some last-minute deals, they're not always guaranteed. Be flexible with your travel plans for a better chance of scoring a bargain.
Is it cheaper to book a MHT to STL flight and hotel package?
Booking a MHT to STL flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip all in one place. Select from our impressive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Manchester-Boston Regional Airport (MHT) to Lambert-St. Louis Intl. Airport (STL)?
Generally, it's possible to cancel or reschedule your MHT to STL flight. However, for bookings made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more information on our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.