$368 Cheap Flights from Myrtle Beach (MYR) to Cape Girardeau (CGI)

View $368 flight on Tue, Aug 19, 2025Opens in a new window

Popular airlines from Myrtle Beach Intl. Airport (MYR) to Cape Girardeau, MO (CGI-Cape Girardeau Municipal)

Cheap Flights from Myrtle Beach to Cape Girardeau (MYR-CGI)

Prices were available within the past 7 days and start at $368 for one-way flights and $878 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sun, Aug 17 - Mon, Aug 18
MYR
Myrtle Beach
CGI
Cape Girardeau
$878 Roundtrip, found 3 hours ago
$878
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Sun, Aug 17 from Myrtle Beach to Cape Girardeau, returning Mon, Aug 18, priced at $878 found 3 hours ago
American Airlines
Sun, Aug 17 - Mon, Aug 18
MYR
Myrtle Beach
CGI
Cape Girardeau
$898 Roundtrip, found 3 hours ago
$898
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Sun, Aug 17 from Myrtle Beach to Cape Girardeau, returning Mon, Aug 18, priced at $898 found 3 hours ago
American Airlines
Sun, Aug 17 - Mon, Aug 18
MYR
Myrtle Beach
CGI
Cape Girardeau
$907 Roundtrip, found 3 hours ago
$907
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Sun, Aug 17 from Myrtle Beach to Cape Girardeau, returning Mon, Aug 18, priced at $907 found 3 hours ago
American Airlines
Sun, Aug 17 - Mon, Aug 18
MYR
Myrtle Beach
CGI
Cape Girardeau
$916 Roundtrip, found 3 hours ago
$916
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Sun, Aug 17 from Myrtle Beach to Cape Girardeau, returning Mon, Aug 18, priced at $916 found 3 hours ago
American Airlines
Sun, Aug 17 - Mon, Aug 18
MYR
Myrtle Beach
CGI
Cape Girardeau
$927 Roundtrip, found 3 hours ago
$927
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Sun, Aug 17 from Myrtle Beach to Cape Girardeau, returning Mon, Aug 18, priced at $927 found 3 hours ago
American Airlines
Sun, Aug 17 - Mon, Aug 18
MYR
Myrtle Beach
CGI
Cape Girardeau
$945 Roundtrip, found 3 hours ago
$945
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Sun, Aug 17 from Myrtle Beach to Cape Girardeau, returning Mon, Aug 18, priced at $945 found 3 hours ago
American Airlines
Sun, Aug 17 - Mon, Aug 18
MYR
Myrtle Beach
CGI
Cape Girardeau
$1,000 Roundtrip, found 3 hours ago
$1,000
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Sun, Aug 17 from Myrtle Beach to Cape Girardeau, returning Mon, Aug 18, priced at $1,000 found 3 hours ago
American Airlines
Sun, Aug 17 - Mon, Aug 18
MYR
Myrtle Beach
CGI
Cape Girardeau
$1,029 Roundtrip, found 3 hours ago
$1,029
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Sun, Aug 17 from Myrtle Beach to Cape Girardeau, returning Mon, Aug 18, priced at $1,029 found 3 hours ago
Flights from Myrtle Beach (MYR) to Cape Girardeau (CGI)
Origin airport
Myrtle Beach Intl.
Destination airport
Cape Girardeau Municipal
Roundtrip price
$877
Distance
646 mi

Myrtle Beach to Cape Girardeau Flights

The cheapest times to fly from Myrtle Beach to Cape Girardeau

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Myrtle Beach to Cape Girardeau are during the month of August. You can find some of the cheapest flights from Myrtle Beach to Cape Girardeau with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Myrtle Beach to Cape Girardeau

Sunday is one of the best days to book for cheap flights from Myrtle Beach to Cape Girardeau: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Myrtle Beach to Cape Girardeau

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Myrtle Beach to Cape Girardeau in 2025. You can also book with separate airlines for your outbound and return journeys, from $368 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Myrtle Beach to Cape Girardeau flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Myrtle Beach to Cape Girardeau airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Myrtle Beach Intl. Airport (MYR) to Cape Girardeau Municipal Airport (CGI) cost?
Get a cheap one-way flight from $368 or cheap return flight from $878 from Myrtle Beach Intl. Airport (MYR) to Cape Girardeau Municipal Airport (CGI) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Myrtle Beach Intl. Airport (MYR) to Cape Girardeau Municipal Airport (CGI)?
Traveling in August can help you save, as it's the cheapest month for flights between MYR and CGI. You'll typically find the lowest prices during off-peak months.
What is the cheapest airline that flies from Myrtle Beach Intl. Airport (MYR) to Cape Girardeau Municipal Airport (CGI)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest MYR to CGI flight.
How many flights per day from Myrtle Beach Intl. Airport (MYR) to Cape Girardeau Municipal Airport (CGI)?
Nonstop flights from Myrtle Beach Intl. Airport (MYR) to Cape Girardeau Municipal Airport (CGI) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your travel details and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MYR to CGI?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Myrtle Beach Intl. Airport (MYR) to Cape Girardeau Municipal Airport (CGI)?
To reach Cape Girardeau Municipal Airport (CGI) on time, book a flight that takes off from Myrtle Beach Intl. Airport (MYR) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Myrtle Beach Intl. Airport (MYR) to Cape Girardeau Municipal Airport (CGI) last-minute?
Last-minute fares from MYR to CGI are usually more expensive. To secure the best rates, start searching for flights as soon as possible. That said, if your travel plans are flexible, it's possible to land a cheap fare just before your departure.
Is it cheaper to book a MYR to CGI flight and hotel package?
Opting for a MYR to CGI flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Pick from our wide range of hotels and then add car rentals, activities and flights to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Myrtle Beach Intl. Airport (MYR) to Cape Girardeau Municipal Airport (CGI)?
In most cases, you can cancel or reschedule your MYR to CGI flight. However, additional fees may apply, especially if you booked over 24 hours ago. Double-check your itinerary for the airline's policies and fees on flight changes, or if you'd like more information, go to our Customer Service portal.

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*Available to One Key members.