
Popular airlines from Myrtle Beach Intl. Airport (MYR) to Popayan (PPN-Guillermo Leon Valencia)
- American Airlines
American Airlines
- United
United
- Southwest Airlines
Southwest Airlines
- Delta
Delta
- Frontier Airlines
Frontier Airlines
- JetBlue Airways
JetBlue Airways
- Alaska Airlines
Alaska Airlines
- Plan, book, fly with confidence
trending down icon Be in the knowGet alerts if flight prices drop or rise*bex rewards loyalty icon Book smarterSave up to 30% on select hotels after you book a flight*one key icon
Origin airport | Myrtle Beach Intl. |
Destination airport | Guillermo Leon Valencia |
Distance | 2162 mi |
Myrtle Beach to Popayan Flights
The cheapest times to fly from Myrtle Beach to Popayan
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Myrtle Beach to Popayan are during the month of . You can find some of the cheapest flights from Myrtle Beach to Popayan with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Myrtle Beach to Popayan
Sunday is one of the best days to book for cheap flights from Myrtle Beach to Popayan: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Myrtle Beach to Popayan
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Myrtle Beach to Popayan in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Myrtle Beach to Popayan flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Myrtle Beach to Popayan airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
Frequently asked questions
Explore a world of travel with Expedia
Lodging
- Cauca Hotels
- Hotels with Restaurants in Cauca
- Popayán Hotels
- Gay friendly Hotels in Popayán
- Resorts & Hotels with Spas in Popayán
- Hotel Wedding Venues Hotels in Popayán
- Apartments in Popayán
- Cabin Rentals in Popayán
- Casino Hotels in Popayán
- Hotels with Bars in Popayán
- Aparthotels in Popayán
- Pet-friendly Hotels in Popayán
- Hotels with Air Conditioning in Popayán
- Hotels near University of Cauca
- Hotels near Clínica La Estancia
- Las Américas Hotels
- Silvia Hotels
- 5 Star Hotels in Silvia
- Pet-friendly Hotels in Silvia
- Hotels near Parque Natural de Purace
- Piendamó Hotels
- Área en litigio Hotels
- La Sierra Hotels
- Extended Stay Hotels in Cauca
- Farmstay in Cauca
- Hotels near Natural History Museum
- El Recuerdo Hotels
- Boutique Hotels in Cauca
- Romantic Hotels in Silvia
- Golf Hotels in Cauca
- Pet-friendly Hotels in Cauca
- Totoró Hotels
- Beach Hotels in Cauca
- Hotels near Ermita Church
- Hotels with an Indoor Pool in Cauca
- Hotels near Museo Arquidiocesano de Arte Religioso
- Historic Hotels in Popayán
- Hotels near Santo Domingo Church
- Hotels with a View in Cauca
- Hotels near Iglesia de San Francisco
- Coconuco Hotels
- Winery Hotels in Cauca
- Adults Only Resorts & in Cauca
- Romantic Hotels in Popayán
- Hotels with a Gym in Cauca
- Rosas Hotels
- Cheap Hotels in Popayán
- Hotels near Popayán Cathedral
- Sotará Hotels
Packages
- Iglesia de San Francisco
- Negret Museum of Modern Art
- Museo Guillermo Leon Valencia
- Visit Cauca
- Cauca Vacations
- Caldas Park
- Visit Popayán
- Popayán Vacations
- Torre del Reloj
- Santo Domingo Church
- Popayán Cathedral
- Clínica La Estancia
- Natural History Museum
- Hospital La Milagrosa
- Visit Silvia
- Silvia Vacations
- Parque Natural de Purace
- Museo Arquidiocesano de Arte Religioso
- Visit Timbío
Cars
- Car rentals near Popayán
- Car rentals near Las Américas
- Car rentals near Calibío
- Car rentals near Rosas
- Car rentals near Silvia
- Sportscar Car Rentals in Silvia
- Avis Rental Cars in Popayán
- Ace Rental Cars in Silvia
- Car rentals near Iglesia de San Francisco
- Car rentals near La Sierra
- Leasys Rental Cars in Popayán
- Car rentals near Coconuco
- Car rentals near Totoró
- Car rentals near Morales
- Car rentals near El Recuerdo
- Pickup Car Rentals in Silvia
- Car rentals near La Vega
- Car rentals near El Tambo
- Car rentals near Cajibío