Cheap Flights from Portland (PDX) to La Serena (LSC)

Popular airlines from Portland International Airport (PDX) to La Serena (LSC-La Florida)

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Cheap Flights from Portland to La Serena (PDX-LSC)

Prices were available within the past 7 days and start at for one-way flights and $1,140 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, Oct 2 - Tue, Oct 14
PDX
Portland
LSC
La Serena
$1,140 Roundtrip, found 2 days ago
$1,140
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Oct 2 from Portland to La Serena, returning Tue, Oct 14, priced at $1,140 found 2 days ago
Alaska Airlines
Thu, Sep 25 - Thu, Oct 9
PDX
Portland
LSC
La Serena
$1,155 Roundtrip, found 2 days ago
$1,155
Roundtrip
found 2 days ago
Select Alaska Airlines flight, departing Thu, Sep 25 from Portland to La Serena, returning Thu, Oct 9, priced at $1,155 found 2 days ago
Delta
Wed, Oct 1 - Tue, Oct 14
PDX
Portland
LSC
La Serena
$1,156 Roundtrip, found 2 days ago
$1,156
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Oct 1 from Portland to La Serena, returning Tue, Oct 14, priced at $1,156 found 2 days ago
LATAM Airlines Group
Thu, Oct 2 - Thu, Oct 16
PDX
Portland
LSC
La Serena
$1,160 Roundtrip, found 2 days ago
$1,160
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Thu, Oct 2 from Portland to La Serena, returning Thu, Oct 16, priced at $1,160 found 2 days ago
Alaska Airlines
Mon, Sep 22 - Thu, Oct 9
PDX
Portland
LSC
La Serena
$1,165 Roundtrip, found 2 days ago
$1,165
Roundtrip
found 2 days ago
Select Alaska Airlines flight, departing Mon, Sep 22 from Portland to La Serena, returning Thu, Oct 9, priced at $1,165 found 2 days ago
LATAM Airlines Group
Wed, Oct 1 - Thu, Oct 16
PDX
Portland
LSC
La Serena
$1,176 Roundtrip, found 2 days ago
$1,176
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Wed, Oct 1 from Portland to La Serena, returning Thu, Oct 16, priced at $1,176 found 2 days ago
Delta
Thu, Sep 25 - Sat, Oct 11
PDX
Portland
LSC
La Serena
$1,180 Roundtrip, found 2 days ago
$1,180
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Sep 25 from Portland to La Serena, returning Sat, Oct 11, priced at $1,180 found 2 days ago
Delta
Sat, Oct 4 - Tue, Oct 14
PDX
Portland
LSC
La Serena
$1,190 Roundtrip, found 2 days ago
$1,190
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Oct 4 from Portland to La Serena, returning Tue, Oct 14, priced at $1,190 found 2 days ago
LATAM Airlines Group
Sun, Sep 28 - Mon, Oct 13
PDX
Portland
LSC
La Serena
$1,195 Roundtrip, found 2 days ago
$1,195
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Sun, Sep 28 from Portland to La Serena, returning Mon, Oct 13, priced at $1,195 found 2 days ago
Delta
Wed, Sep 24 - Sat, Oct 11
PDX
Portland
LSC
La Serena
$1,196 Roundtrip, found 2 days ago
$1,196
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Sep 24 from Portland to La Serena, returning Sat, Oct 11, priced at $1,196 found 2 days ago
Delta
Mon, Sep 8 - Wed, Sep 24
PDX
Portland
LSC
La Serena
$1,200 Roundtrip, found 2 days ago
$1,200
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Sep 8 from Portland to La Serena, returning Wed, Sep 24, priced at $1,200 found 2 days ago
Alaska Airlines
Mon, Sep 22 - Fri, Oct 10
PDX
Portland
LSC
La Serena
$1,205 Roundtrip, found 2 days ago
$1,205
Roundtrip
found 2 days ago
Select Alaska Airlines flight, departing Mon, Sep 22 from Portland to La Serena, returning Fri, Oct 10, priced at $1,205 found 2 days ago
Alaska Airlines
Mon, Sep 8 - Thu, Sep 25
PDX
Portland
LSC
La Serena
$1,210 Roundtrip, found 2 days ago
$1,210
Roundtrip
found 2 days ago
Select Alaska Airlines flight, departing Mon, Sep 8 from Portland to La Serena, returning Thu, Sep 25, priced at $1,210 found 2 days ago
LATAM Airlines Group
Tue, Sep 2 - Thu, Sep 25
PDX
Portland
LSC
La Serena
$1,215 Roundtrip, found 2 days ago
$1,215
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, Sep 2 from Portland to La Serena, returning Thu, Sep 25, priced at $1,215 found 2 days ago
LATAM Airlines Group
Wed, Oct 1 - Sat, Oct 18
PDX
Portland
LSC
La Serena
$1,216 Roundtrip, found 2 days ago
$1,216
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Wed, Oct 1 from Portland to La Serena, returning Sat, Oct 18, priced at $1,216 found 2 days ago
LATAM Airlines Group
Tue, Sep 2 - Sun, Sep 21
PDX
Portland
LSC
La Serena
$1,220 Roundtrip, found 2 days ago
$1,220
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, Sep 2 from Portland to La Serena, returning Sun, Sep 21, priced at $1,220 found 2 days ago
Alaska Airlines
Sun, Aug 24 - Wed, Sep 10
PDX
Portland
LSC
La Serena
$1,225 Roundtrip, found 2 days ago
$1,225
Roundtrip
found 2 days ago
Select Alaska Airlines flight, departing Sun, Aug 24 from Portland to La Serena, returning Wed, Sep 10, priced at $1,225 found 2 days ago
LATAM Airlines Group
Sun, Aug 31 - Tue, Sep 16
PDX
Portland
LSC
La Serena
$1,230 Roundtrip, found 2 days ago
$1,230
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Sun, Aug 31 from Portland to La Serena, returning Tue, Sep 16, priced at $1,230 found 2 days ago
Delta
Fri, Sep 5 - Wed, Sep 24
PDX
Portland
LSC
La Serena
$1,240 Roundtrip, found 2 days ago
$1,240
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Sep 5 from Portland to La Serena, returning Wed, Sep 24, priced at $1,240 found 2 days ago
LATAM Airlines Group
Fri, Oct 3 - Tue, Oct 14
PDX
Portland
LSC
La Serena
$1,247 Roundtrip, found 2 days ago
$1,247
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Fri, Oct 3 from Portland to La Serena, returning Tue, Oct 14, priced at $1,247 found 2 days ago

Alternative airports near La Serena

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to La Florida LSC. Cheapest and Closest option available. Average driving time to city center is 7 minutes. Flights from $1,300
LSC
La Florida
CheapestClosest
Average driving time to city center7 min
Flights from $1,300
Flights from Portland (PDX) to La Serena (LSC)
Origin airport
Portland Intl.
Destination airport
La Florida
Airlines serving
LATAM Airlines Group
Roundtrip price
$1,139
Distance
6129 mi

Portland to La Serena Flights

The cheapest times to fly from Portland to La Serena

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Portland to La Serena are during the month of October. You can find some of the cheapest flights from Portland to La Serena with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Portland to La Serena

Sunday is one of the best days to book for cheap flights from Portland to La Serena: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Portland to La Serena

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Portland to La Serena in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Portland to La Serena flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Portland to La Serena airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Portland Intl. Airport (PDX) to La Florida Airport (LSC) cost?
Get a cheap one-way flight or cheap return flight from $1,140 from Portland Intl. Airport (PDX) to La Florida Airport (LSC) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Portland Intl. Airport (PDX) to La Florida Airport (LSC)?
October is the least expensive month to fly from PDX to LSC. Traveling during an off-peak travel window is often the key to landing a great deal.
What is the cheapest airline that flies from Portland Intl. Airport (PDX) to La Florida Airport (LSC)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest PDX to LSC flight.
How many flights per day from Portland Intl. Airport (PDX) to La Florida Airport (LSC)?
You'll have to book a flight with a layover if you're traveling from Portland Intl. Airport (PDX) to La Florida Airport (LSC). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to find an option that works for you.
What day of the week has the most flights from PDX to LSC?
Usually you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can change based on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Portland Intl. Airport (PDX) to La Florida Airport (LSC)?
To touch down at La Florida Airport (LSC) on schedule, choose a flight that leaves Portland Intl. Airport (PDX) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Portland Intl. Airport (PDX) to La Florida Airport (LSC) last-minute?
Last-minute fares from PDX to LSC are generally more expensive. For the best rates, start looking for flights ahead of time. That being said, if you can play around with your travel dates, you may find a cheap fare right before your journey.
Is it cheaper to book a PDX to LSC flight and hotel package?
Compared with arranging hotels and flights separately, booking a PDX to LSC flight and hotel package with Expedia could lead to significant savings. Better yet, having everything in one convenient place takes the hassle out of travel planning. Just pick your flights and select from our extensive range of hotels, then tailor your trip with other add-ons like car rentals and activities.
Can I cancel or change the date of my flight from Portland Intl. Airport (PDX) to La Florida Airport (LSC)?
It's generally possible to cancel or reschedule your PDX to LSC flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.