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$117 Cheap Flights from Portland (PWM) to Greenville (GSP)

Photo by Visit Greenville, South Carolina
Open Photo by Visit Greenville, South Carolina

Cheap Flights from Portland to Greenville (PWM-GSP)

Prices were available within the past 7 days and start at $117 for one-way flights and $237 for roundtrip, for the period specified. Prices and availability are subject to change.

Alternative airports near Greenville

Prices were available within the past 7 days. Prices and availability are subject to change.

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Portland (PWM) to Greenville (GSP) at a glance

Travel from Portland (PWM) to Greenville (GSP) with a range of airlines on this short domestic route. Compare options from both full-service and budget carriers to discover the best flights to Greenville that align with your travel plans, schedule, and budget. Whether you're planning a trip from Maine to Greenville for sightseeing or exploring the area’s vibrant neighborhoods, you’ll find all the essential details for your journey from Portland International Jetport Airport to Greenville-Spartanburg International Airport.

  • Fastest flight duration: around 4h 15m non-stop
  • Route distance: roughly 900 miles (1,450 km)
  • Flights per week: around 9 departures on average
  • Typical fares (one-way): economy tickets often range from $105–$400, depending on seasonality and how far ahead you book

Flights from Portland International Jetport Airport (PWM) to Greenville-Spartanburg International Airport (GSP)

Based on the latest traveler bookings, here are the top airlines preferred for flights from Portland to Greenville, featuring both one-stop and non-stop options. Many travelers opt for convenient layovers at key airports like Philadelphia International Airport (PHL, approximately 1-hour layover), LaGuardia Airport (LGA, about 1 hour and 15 minutes layover), and Baltimore Washington International Thurgood Marshall Airport (BWI, around 1-hour layover). This variety allows you to balance price, total travel time, and cabin class to create the best itinerary for your journey.

  • American Airlines: This full-service airline provides one-stop options, with one-way ticket prices generally falling between $120 and $385. It represents about 49% of departures along this route, featuring an in-flight duration of 3 hours and 30 minutes, totaling approximately 4 hours and 45 minutes when including layover time.
  • Delta: As a full-service carrier, Delta offers one-stop flights with one-way fares ranging from $120 to $410. It makes up roughly 18% of departures on this route, with a flight time of 3 hours and 30 minutes and a total travel time of about 4 hours and 45 minutes, factoring in layovers.
  • Southwest Airlines: This budget-friendly airline provides one-stop services, with one-way fares typically priced between $150 and $400. It accounts for approximately 13% of flights on this route, featuring an in-flight duration of 3 hours and 30 minutes, and a total travel time of around 4 hours and 45 minutes, including layovers.
  • United: A full-service airline, United offers one-stop travel options with one-way fares generally ranging from $165 to $425. It constitutes about 11% of departures for this route, with a flight time of 3 hours and 30 minutes, leading to a total journey time of roughly 4 hours and 45 minutes, including layovers.
  • Breeze: As a low-cost airline, Breeze provides non-stop services, featuring one-way fares that typically range from $105 to $340. It covers around 8% of departures on this route, with a total travel duration of 4 hours and 15 minutes.

Best time to fly from Portland (PWM) to Greenville (GSP)

The most popular months for travelers flying from Portland to Greenville are March, June, and September, when peak temperatures in Greenville reach up to 76.1°F in June. If you prefer quieter travel, consider August, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 77.5°F. For better deals, May usually offers the lowest average one-way fare around $166. Flight availability peaks in June, with approximately 12 flights per week, making it easier to find convenient departure times.

  • Cheapest time to fly: May usually offers good deals with average one-way fare around $166, roughly 27% cheaper than the yearly average.
  • Another budget-friendly time to fly: September typically offers an average one-way fare of around $187.
  • Most flight options: June has the highest number of flights from Portland to Greenville, with approximately 12 flights per week, giving you more flexibility in scheduling your trip.
MonthTemperatureDemandWeekly FlightsAverage one-way Fare
January41.4°F (5.2°C)Moderately Low9$200
February45.3°F (7.4°C)Average9$247
March51.8°F (11.0°C)Moderately High9$243
April59.9°F (15.5°C)Average8$245
May68.4°F (20.2°C)Average8$166
June76.1°F (24.5°C)Moderately High12$209
July79.5°F (26.4°C)Average11$275
August77.5°F (25.3°C)Moderately Low8$191
September72.3°F (22.4°C)Moderately High11$187
October61.9°F (16.6°C)Average10$259
November51.1°F (10.6°C)Average11$246
December45.3°F (7.4°C)Moderately Low8$272

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from Portland (PWM) to Greenville (GSP)

  • Portland to Greenville (PWM-GMU): Greenville Downtown Airport (GMU) is located approximately 8 miles from Greenville-Spartanburg International Airport (GSP), providing convenient access for travelers.
  • Sanford to Greenville (SFM-GSP): Sanford Seacoast Regional Airport (SFM) is roughly 26 miles from Portland International Jetport Airport (PWM), making it a practical departure point for flights.
  • Sanford to Spartanburg (SFM-SPA): Sanford Seacoast Regional Airport (SFM) is about 26 miles from Portland International Jetport Airport (PWM), while Spartanburg Downtown Memorial Airport (SPA) lies nearly 15 miles from Greenville-Spartanburg International Airport (GSP).

How to find the best prices for flights from Portland (PWM) to Greenville (GSP)

Getting some of the best deals on flights from Portland to Greenville is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking at least two months in advance, although most travelers book their flights two to eight weeks ahead. Departures in the afternoon, from 12 PM to 6 PM, tend to be more affordable and are also the most popular. Additionally, flying on Thursday offers both lower prices and is the favored travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Greenville hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Greenville-Spartanburg International Airport from Portland International Jetport Airport

Greenville welcomes travelers from Portland with a range of transport options based on price, convenience, and proximity. Greenville city center is approximately a 20-minute drive (covering about 16 miles) from Greenville-Spartanburg International Airport, depending on traffic. Here's how to reach Greenville efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Greenville, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Greenville-Spartanburg International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Greenville-Spartanburg International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.

Portland to Greenville Flights

The cheapest times to fly from Portland to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Portland to Greenville are during the month of November. You can find some of the cheapest flights from Portland to Greenville with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Portland to Greenville

Sunday is one of the best days to book for cheap flights from Portland to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Portland to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Portland to Greenville in 2026. You can also book with separate airlines for your outbound and return journeys, from $117 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Portland to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Portland to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently Asked Questions

How much does a flight from Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) cost?

You can find cheap one-way flights from $117 and cheap return flights $237 Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) with Expedia. One-way flights generally range between $148 and $586, and roundtrip flights usually range from $352 to $1124. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) ticket fares go up or down.

*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.

What is the cheapest month to fly from Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

August is the cheapest month to fly from Portland, ME (PWM) to Greenville, SC (GSP), with average round-trip fares around $322. This price is about 21% lower than the average throughout the year, as travel demand typically decreases after the summer season. Other economical months to consider are September and October.

*Averages based on flights available on Expedia in the last year.

Which airlines fly direct from Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

Enter PWM to GSP and your travel dates, then apply the 'Nonstop' filter to see only direct flights.

How do I find cheap flights from Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

To find a cheap flight from Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.

What is the best time to fly from Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

The best time to fly from Portland, ME (PWM) to Greenville, SC (GSP) is typically in August or September. During these months, you can expect average return flight prices around $322. August is ideal for budget-conscious travelers, while September offers a good balance of price and travel options, making it a popular choice.

*Prices based on flights available on Expedia in the last year.

What is the earliest flight from Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

The earliest flight from Portland International Jetport (PWM) to Greenville-Spartanburg International Airport (GSP) typically departs at 5:05 AM, operated by American Airlines. This seasonal service is active in June and July, allowing you to make the most of your time in Greenville. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.

What are the most popular departure times for flights from Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

The most popular departure times for flights from Portland, ME (PWM) to Greenville, SC (GSP) are in the early morning, from 6am to 9am. About 33% of passengers prefer this time window. Many major carriers, including American Airlines, Delta and United, offer flights during this window. This timing works well because it allows you to arrive in Greenville with plenty of time to start your day.

How long does it take to fly from Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

Flying from PWM to GSP with a connection usually takes about 5 hours, traveling roughly 877 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.

Can you fly business or first class from Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

You can fly first class between PWM and GSP. First class cabins are available on:

  • Delta Air Lines
  • American Airlines
  • United Airlines

How do I earn miles on a Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight with Expedia?

It's easy to earn miles on a Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

What airports do you fly into for Greenville from Portland Intl. Jetport (PWM)?

When traveling from Portland Intl. Jetport (PWM) to Greenville, you can fly into Pitt-Greenville (PGV) and Greenville-Spartanburg Intl. (GSP). Some flights may connect through major hubs like Philadelphia Intl. (PHL), Ronald Reagan Washington National (DCA), LaGuardia (LGA) before reaching Greenville. Compare routes and airports on Expedia to find the best flight options for your travel plans.

Is it cheaper to buy a plane ticket from Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) at the last minute?

Typically, booking a last minute flight from Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.

Is it cheaper to book a Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package?

Securing a Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.

Can I cancel or change the date of my flight from Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

If you booked your Portland, ME (PWM-Portland Intl. Jetport) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Portland Intl. Jetport Airport
Destination airport
Greenville-Spartanburg Intl. Airport
Distance
876 miles away
Airlines serving
American Airlines, Delta, United, Southwest Airlines, Breeze Airways
Popular airline
American Airlines
Roundtrip price
$237
Average flight time
4 hours 20 mins
*Available to One Key members.