$129 Cheap Flights from Portland (PWM) to St. Louis (STL)

View $129 flight on Thu, Jan 8, 2026Opens in a new window

Popular airlines from Portland Intl. Jetport Airport (PWM) to St. Louis Lambert Intl. Airport (STL)

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Cheap Flights from Portland to St. Louis (PWM-STL)

Prices were available within the past 7 days and start at $129 for one-way flights and $238 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Oct 1 - Wed, Oct 8
PWM
Portland
STL
St. Louis
$238 Roundtrip, found 5 days ago
$238
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Oct 1 from Portland to St. Louis, returning Wed, Oct 8, priced at $238 found 5 days ago
American Airlines
Wed, Oct 1 - Wed, Oct 8
PWM
Portland
STL
St. Louis
$241 Roundtrip, found 5 days ago
$241
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Oct 1 from Portland to St. Louis, returning Wed, Oct 8, priced at $241 found 5 days ago
Southwest Airlines
Wed, Oct 1 - Wed, Oct 8
PWM
Portland
STL
St. Louis
$244 Roundtrip, found 5 days ago
$244
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Wed, Oct 1 from Portland to St. Louis, returning Wed, Oct 8, priced at $244 found 5 days ago
Delta
Sat, Oct 4 - Mon, Oct 6
PWM
Portland
STL
St. Louis
$247 Roundtrip, found 5 days ago
$247
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Oct 4 from Portland to St. Louis, returning Mon, Oct 6, priced at $247 found 5 days ago
Southwest Airlines
Wed, Oct 1 - Wed, Oct 8
PWM
Portland
STL
St. Louis
$249 Roundtrip, found 5 days ago
$249
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Wed, Oct 1 from Portland to St. Louis, returning Wed, Oct 8, priced at $249 found 5 days ago
United
Wed, Oct 1 - Wed, Oct 8
PWM
Portland
STL
St. Louis
$256 Roundtrip, found 5 days ago
$256
Roundtrip
found 5 days ago
Select United flight, departing Wed, Oct 1 from Portland to St. Louis, returning Wed, Oct 8, priced at $256 found 5 days ago
Delta
Thu, Jan 8 - Mon, Jan 12
PWM
Portland
STL
St. Louis
$257 Roundtrip, found 6 days ago
$257
Roundtrip
found 6 days ago
Select Delta flight, departing Thu, Jan 8 from Portland to St. Louis, returning Mon, Jan 12, priced at $257 found 6 days ago
Southwest Airlines
Wed, Oct 1 - Wed, Oct 8
PWM
Portland
STL
St. Louis
$259 Roundtrip, found 5 days ago
$259
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Wed, Oct 1 from Portland to St. Louis, returning Wed, Oct 8, priced at $259 found 5 days ago
Southwest Airlines
Wed, Oct 1 - Wed, Oct 8
PWM
Portland
STL
St. Louis
$264 Roundtrip, found 5 days ago
$264
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Wed, Oct 1 from Portland to St. Louis, returning Wed, Oct 8, priced at $264 found 5 days ago
Delta
Fri, Oct 3 - Wed, Oct 8
PWM
Portland
STL
St. Louis
$267 Roundtrip, found 5 days ago
$267
Roundtrip
found 5 days ago
Select Delta flight, departing Fri, Oct 3 from Portland to St. Louis, returning Wed, Oct 8, priced at $267 found 5 days ago

Find the cheapest month to fly from Portland (PWM) to St. Louis (STL)

September is typically the cheapest month to fly

From $209 - $630 per traveler.
Flights from Portland (PWM) to St. Louis (STL)
Origin airport
Portland Intl. Jetport
Destination airport
Lambert-St. Louis Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$238
Distance
1093 mi

Portland to St. Louis Flights

The cheapest times to fly from Portland to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Portland to St. Louis are during the month of October. You can find some of the cheapest flights from Portland to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Portland to St. Louis

Sunday is one of the best days to book for cheap flights from Portland to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Portland to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Portland to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $129 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Portland to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Portland to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Portland Intl. Jetport Airport (PWM) to Lambert-St. Louis Intl. Airport (STL) cost?
Grab a cheap one-way flight from $129 or cheap return flight from $238 from Portland Intl. Jetport Airport (PWM) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Portland Intl. Jetport Airport (PWM) to Lambert-St. Louis Intl. Airport (STL)?
Traveling in October is a great way to save, as it's the cheapest month for flights between PWM and STL. You'll typically find the lowest prices during off-peak months.
What is the cheapest airline that flies from Portland Intl. Jetport Airport (PWM) to Lambert-St. Louis Intl. Airport (STL)?
Use the filter tool on Expedia to compare different airlines and find the most affordable carrier that'll take you from PWM to STL. Then, sort your results by "Price (lowest to highest)" to score a good deal.
How many flights per day from Portland Intl. Jetport Airport (PWM) to Lambert-St. Louis Intl. Airport (STL)?
You'll have to take a flight with a layover if you're traveling from Portland Intl. Jetport Airport (PWM) to Lambert-St. Louis Intl. Airport (STL). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from PWM to STL?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can vary based on various factors, including the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Portland Intl. Jetport Airport (PWM) to Lambert-St. Louis Intl. Airport (STL)?
To avoid possible delays on the Portland Intl. Jetport Airport (PWM) to Lambert-St. Louis Intl. Airport (STL) route, aim to fly before 3 PM. Later departures have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Portland Intl. Jetport Airport (PWM) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Holding off until right before your break to book a flight from PWM to STL often results in higher prices. While you may come across some last-minute discounts, they aren't always guaranteed. Be flexible with your itinerary for a better chance of snagging a bargain.
Is it cheaper to book a PWM to STL flight and hotel package?
Compared with arranging hotels and flights separately, booking a PWM to STL flight and hotel package with Expedia could result in significant savings. Better still, having everything in one place will take the hassle out of travel planning. Simply secure your flights and select from our wide range of hotels, then personalize your trip with other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Portland Intl. Jetport Airport (PWM) to Lambert-St. Louis Intl. Airport (STL)?
In most instances, you can cancel or reschedule your PWM to STL flight. However, there may be additional charges, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline's fees and guidelines on flight changes, or if you'd like more information, go to our Customer Service portal.

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*Available to One Key members.