$141 Cheap Flights from San Diego (SAN) to Panama City (PTY)

Popular airlines from San Diego Intl. Airport (SAN) to Tocumen Intl. Airport (PTY)

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Cheap Flights from San Diego to Panama City (SAN-PTY)

Prices were available within the past 7 days and start at $141 for one-way flights and $341 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Delta
United
United
United
United
American Airlines
United
United
avianca

Find the cheapest month to fly from San Diego (SAN) to Panama City (PTY)

September is typically the cheapest month to fly

From $340 - $903 per traveler.

Graph displaying average flight prices per month

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Flights from San Diego (SAN) to Panama City (PTY)
Origin airport
San Diego Intl.
Destination airport
Tocumen Intl.
Airlines serving
American Airlines, Copa, Delta, United, avianca
Roundtrip price
$340
Distance
2911 mi
Average flight time
5 hours 22 mins

San Diego to Panama City Flights

The cheapest times to fly from San Diego to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from San Diego to Panama City are during the month of October. You can find some of the cheapest flights from San Diego to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from San Diego to Panama City

Sunday is one of the best days to book for cheap flights from San Diego to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from San Diego to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from San Diego to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $141 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap San Diego to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your San Diego to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from San Diego Intl. Airport (SAN) to Tocumen Intl. Airport (PTY) cost?
Cheap return fares from San Diego Intl. Airport (SAN) to Tocumen Intl. Airport (PTY) start at $341. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Copa flight leaving SAN on August 6 2025 and touching down at PTY. The price was last updated on July 11 2025 and has not changed since.
What is the cheapest month to fly from SAN to PTY?
The cheapest flights from SAN to PTY are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from SAN to PTY?
Fly from SAN to PTY with Copa. This airline currently offers the cheapest one-way fare for this route, starting at $360. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from SAN on July 21 2025. Prices were last updated on July 11 2025 and have not changed since.
How many flights per day from San Diego Intl. Airport (SAN) to Tocumen Intl. Airport (PTY)?
Direct flights from San Diego Intl. Airport (SAN) to Tocumen Intl. Airport (PTY) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel dates and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from SAN to PTY?
Generally you'll find the widest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can vary based on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from San Diego Intl. Airport (SAN) to Tocumen Intl. Airport (PTY)?
To avoid possible delays on the San Diego Intl. Airport (SAN) to Tocumen Intl. Airport (PTY) route, aim to fly before 3 PM. Departures after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from San Diego Intl. Airport (SAN) to Tocumen Intl. Airport (PTY) last-minute?
Waiting until just before your departure to book a flight from SAN to PTY often results in higher prices. While you may come across some last-minute discounts, they're not always guaranteed. Keep your travel schedule open for a better chance of scoring a bargain.
Is it cheaper to book a SAN to PTY flight and hotel package?
Compared with arranging flights and hotels separately, booking a SAN to PTY flight and hotel package with Expedia could result in significant savings. Better still, having everything in one convenient place will take the stress out of planning your trip. Simply secure your flights and select from our wide range of hotels, then tailor your trip with other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from San Diego Intl. Airport (SAN) to Tocumen Intl. Airport (PTY)?
If you booked your SAN to PTY flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of fare you have, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

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