$449 Cheap Flights from San Antonio (SAT) to Santiago (SCL)

View $449 flight on Tue, Mar 24, 2026Opens in a new window

Popular airlines from San Antonio International Airport (SAT) to Santiago Intl. Airport (SCL)

Cheap Flights from San Antonio to Santiago (SAT-SCL)

Prices were available within the past 7 days and start at $449 for one-way flights and $714 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Jan 6 - Thu, Jan 22
SAT
San Antonio
SCL
Santiago
$714 Roundtrip, found 1 hour ago
$714
Roundtrip
found 1 hour ago
Select Delta flight, departing Tue, Jan 6 from San Antonio to Santiago, returning Thu, Jan 22, priced at $714 found 1 hour ago
United
Wed, Dec 31 - Wed, Jan 21
SAT
San Antonio
SCL
Santiago
$714 Roundtrip, found 1 hour ago
$714
Roundtrip
found 1 hour ago
Select United flight, departing Wed, Dec 31 from San Antonio to Santiago, returning Wed, Jan 21, priced at $714 found 1 hour ago
United
Thu, Mar 5 - Wed, Mar 11
SAT
San Antonio
SCL
Santiago
$719 Roundtrip, found 12 hours ago
$719
Roundtrip
found 12 hours ago
Select United flight, departing Thu, Mar 5 from San Antonio to Santiago, returning Wed, Mar 11, priced at $719 found 12 hours ago
United
Tue, Jan 6 - Tue, Feb 3
SAT
San Antonio
SCL
Santiago
$720 Roundtrip, found 1 day ago
$720
Roundtrip
found 1 day ago
Select United flight, departing Tue, Jan 6 from San Antonio to Santiago, returning Tue, Feb 3, priced at $720 found 1 day ago
Delta
Tue, Jan 6 - Mon, Jan 19
SAT
San Antonio
SCL
Santiago
$723 Roundtrip, found 1 hour ago
$723
Roundtrip
found 1 hour ago
Select Delta flight, departing Tue, Jan 6 from San Antonio to Santiago, returning Mon, Jan 19, priced at $723 found 1 hour ago
Delta
Sun, Mar 15 - Thu, Mar 26
SAT
San Antonio
SCL
Santiago
$723 Roundtrip, found 20 hours ago
$723
Roundtrip
found 20 hours ago
Select Delta flight, departing Sun, Mar 15 from San Antonio to Santiago, returning Thu, Mar 26, priced at $723 found 20 hours ago
United
Tue, Jan 6 - Tue, Feb 3
SAT
San Antonio
SCL
Santiago
$727 Roundtrip, found 19 hours ago
$727
Roundtrip
found 19 hours ago
Select United flight, departing Tue, Jan 6 from San Antonio to Santiago, returning Tue, Feb 3, priced at $727 found 19 hours ago
American Airlines
Wed, Dec 10 - Wed, Dec 17
SAT
San Antonio
SCL
Santiago
$734 Roundtrip, found 5 days ago
$734
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Dec 10 from San Antonio to Santiago, returning Wed, Dec 17, priced at $734 found 5 days ago
LATAM Airlines Group
Tue, Jan 6 - Tue, Feb 10
SAT
San Antonio
SCL
Santiago
$734 Roundtrip, found 1 day ago
$734
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Tue, Jan 6 from San Antonio to Santiago, returning Tue, Feb 10, priced at $734 found 1 day ago
Aeromexico
Mon, Jan 19 - Mon, Mar 2
SAT
San Antonio
SCL
Santiago
$782 Roundtrip, found 4 days ago
$782
Roundtrip
found 4 days ago
Select Aeromexico flight, departing Mon, Jan 19 from San Antonio to Santiago, returning Mon, Mar 2, priced at $782 found 4 days ago

Alternative airports near Santiago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Arturo Merino Benitez SCL. Cheapest and Closest option available. Average driving time to city center is 17 minutes. Flights from $1,246
SCL
Arturo Merino Benitez
CheapestClosest
Average driving time to city center17 min
Flights from $1,246
Flights from San Antonio (SAT) to Santiago (SCL)
Origin airport
San Antonio Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Aeromexico, Air Canada, American Airlines, Delta, LATAM Airlines Group, United
Roundtrip price
$714
Distance
4709 mi

San Antonio to Santiago Flights

The cheapest times to fly from San Antonio to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from San Antonio to Santiago are during the month of January. You can find some of the cheapest flights from San Antonio to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from San Antonio to Santiago

Sunday is one of the best days to book for cheap flights from San Antonio to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from San Antonio to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from San Antonio to Santiago in 2026. You can also book with separate airlines for your outbound and return journeys, from $449 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap San Antonio to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your San Antonio to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from San Antonio Intl. Airport (SAT) to Arturo Merino Benitez Airport (SCL) cost?
Snag a cheap one-way flight from $449 or cheap return flight from $714 from San Antonio Intl. Airport (SAT) to Arturo Merino Benitez Airport (SCL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from San Antonio Intl. Airport (SAT) to Arturo Merino Benitez Airport (SCL)?
January is the most affordable month to fly from SAT to SCL. Timing your trip outside of the busy season is often the key to landing a great deal.
What is the cheapest airline that flies from San Antonio Intl. Airport (SAT) to Arturo Merino Benitez Airport (SCL)?
To find the cheapest airline that'll fly you from SAT to SCL, use Expedia's filter tool. Tailor your search based on your travel needs, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from San Antonio Intl. Airport (SAT) to Arturo Merino Benitez Airport (SCL)?
You'll need to hop on a flight with a layover when traveling from San Antonio Intl. Airport (SAT) to Arturo Merino Benitez Airport (SCL). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to find the best option for your trip.
What day of the week has the most flights from SAT to SCL?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from San Antonio Intl. Airport (SAT) to Arturo Merino Benitez Airport (SCL)?
Book a flight from San Antonio Intl. Airport (SAT) to Arturo Merino Benitez Airport (SCL) that leaves before 3 PM to reduce the risk of cancellations. Departures after this hour have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from San Antonio Intl. Airport (SAT) to Arturo Merino Benitez Airport (SCL) last-minute?
Booking your flight from SAT to SCL shortly before your getaway is typically more expensive. But if there's some wiggle room with your schedule, you could land a cheap last-minute fare.
Is it cheaper to book a SAT to SCL flight and hotel package?
You can save money by securing a SAT to SCL flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. After selecting your ideal accommodations and flights, you can add extras such as car rentals, activities and tours.
Can I cancel or change the date of my flight from San Antonio Intl. Airport (SAT) to Arturo Merino Benitez Airport (SCL)?
Generally, it's possible to cancel or reschedule your SAT to SCL flight. However, for bookings made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more details on our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.