$106 Cheap Flights from Santo Domingo (SDQ) to Medellín (MDE)

View $106 flight on Mon, Sep 1, 2025Opens in a new window

Popular airlines from Las Americas Intl. Airport (SDQ) to Jose Maria Cordova Intl. Airport (MDE)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • one key icon

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Santo Domingo to Medellín (SDQ-MDE)

Prices were available within the past 7 days and start at $106 for one-way flights and $225 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Arajet
Fri, Sep 5 - Mon, Sep 8
SDQ
Santo Domingo
MDE
Medellin
$225 Roundtrip, found 1 hour ago
$225
Roundtrip
found 1 hour ago
Select Arajet flight, departing Fri, Sep 5 from Santo Domingo to Medellin, returning Mon, Sep 8, priced at $225 found 1 hour ago
Arajet
Fri, Oct 3 - Wed, Dec 31
SDQ
Santo Domingo
MDE
Medellin
$226 Roundtrip, found 16 hours ago
$226
Roundtrip
found 16 hours ago
Select Arajet flight, departing Fri, Oct 3 from Santo Domingo to Medellin, returning Wed, Dec 31, priced at $226 found 16 hours ago
Arajet
Sun, Feb 1 - Fri, Feb 6
SDQ
Santo Domingo
MDE
Medellin
$227 Roundtrip, found 3 hours ago
$227
Roundtrip
found 3 hours ago
Select Arajet flight, departing Sun, Feb 1 from Santo Domingo to Medellin, returning Fri, Feb 6, priced at $227 found 3 hours ago
Arajet
Wed, Sep 3 - Mon, Sep 8
SDQ
Santo Domingo
MDE
Medellin
$233 Roundtrip, found 1 hour ago
$233
Roundtrip
found 1 hour ago
Select Arajet flight, departing Wed, Sep 3 from Santo Domingo to Medellin, returning Mon, Sep 8, priced at $233 found 1 hour ago
Arajet
Fri, Oct 31 - Tue, Nov 4
SDQ
Santo Domingo
MDE
Medellin
$234 Roundtrip, found 1 hour ago
$234
Roundtrip
found 1 hour ago
Select Arajet flight, departing Fri, Oct 31 from Santo Domingo to Medellin, returning Tue, Nov 4, priced at $234 found 1 hour ago
Arajet
Tue, Nov 11 - Fri, Nov 14
SDQ
Santo Domingo
MDE
Medellin
$235 Roundtrip, found 12 hours ago
$235
Roundtrip
found 12 hours ago
Select Arajet flight, departing Tue, Nov 11 from Santo Domingo to Medellin, returning Fri, Nov 14, priced at $235 found 12 hours ago
BEK AIR
Tue, Sep 2 - Fri, Sep 5
SDQ
Santo Domingo
MDE
Medellin
$243 Roundtrip, found 8 hours ago
$243
Roundtrip
found 8 hours ago
Select BEK AIR flight, departing Tue, Sep 2 from Santo Domingo to Medellin, returning Fri, Sep 5, priced at $243 found 8 hours ago
Copa
Mon, Sep 1 - Wed, Sep 10
SDQ
Santo Domingo
MDE
Medellin
$265 Roundtrip, just found
$265
Roundtrip
just found
Select Copa flight, departing Mon, Sep 1 from Santo Domingo to Medellin, returning Wed, Sep 10, priced at $265 just found
avianca
Fri, Oct 3 - Mon, Oct 20
SDQ
Santo Domingo
MDE
Medellin
$321 Roundtrip, found 1 hour ago
$321
Roundtrip
found 1 hour ago
Select avianca flight, departing Fri, Oct 3 from Santo Domingo to Medellin, returning Mon, Oct 20, priced at $321 found 1 hour ago
World Ticket Ltd
Fri, Sep 5 - Mon, Sep 8
SDQ
Santo Domingo
MDE
Medellin
$398 Roundtrip, found 1 hour ago
$398
Roundtrip
found 1 hour ago
Select World Ticket Ltd flight, departing Fri, Sep 5 from Santo Domingo to Medellin, returning Mon, Sep 8, priced at $398 found 1 hour ago

Find the cheapest month to fly from Santo Domingo (SDQ) to Medellín (MDE)

June is typically the cheapest month to fly

From $202 - $357 per traveler.

Graph displaying average flight prices per month

Alternative airports near Medellín

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Jose Maria Cordova Intl. MDE. Cheapest option available. Average driving time to city center is 29 minutes. Flights from $265
MDE
Jose Maria Cordova Intl.
Cheapest
Average driving time to city center29 min
Flights from $265
Flights from Santo Domingo (SDQ) to Medellín (MDE)
Origin airport
Las Americas Intl.
Destination airport
José María Córdova Intl.
Airlines serving
American Airlines, Arajet, Copa, Hahn Air Technologies, JetBlue Airways, United, World Ticket Ltd, avianca
Roundtrip price
$224
Distance
931 mi
Average flight time
1 hour 33 mins

Santo Domingo to Medellín Flights

The cheapest times to fly from Santo Domingo to Medellín

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santo Domingo to Medellín are during the month of September. You can find some of the cheapest flights from Santo Domingo to Medellín with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santo Domingo to Medellín

Sunday is one of the best days to book for cheap flights from Santo Domingo to Medellín: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santo Domingo to Medellín

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santo Domingo to Medellín in 2025. You can also book with separate airlines for your outbound and return journeys, from $106 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santo Domingo to Medellín flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santo Domingo to Medellín airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Las Americas Intl. Airport (SDQ) to Jose Maria Cordova Intl. Airport (MDE) cost?
You can pick up cheap return flights starting from $225 from Las Americas Intl. Airport (SDQ) to Jose Maria Cordova Intl. Airport (MDE). This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Arajet flight leaving SDQ on August 19 2025 and touching down at MDE. The price was last updated on July 23 2025 and has not changed since.
What is the cheapest month to fly from SDQ to MDE?
The cheapest flights from SDQ to MDE are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Las Americas Intl. Airport (SDQ) to Jose Maria Cordova Intl. Airport (MDE)?
If you're departing from Las Americas Intl. Airport (SDQ), you can catch a nonstop flight to Jose Maria Cordova Intl. Airport (MDE) with Arajet.
What is the cheapest airline that flies from SDQ to MDE?
Jet off from SDQ to MDE with Arajet. This carrier currently offers the lowest one-way fare for this route, starting from $106. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from SDQ on October 3 2025. Prices were last updated on July 23 2025 and have not changed since.
How many flights per day from Las Americas Intl. Airport (SDQ) to Jose Maria Cordova Intl. Airport (MDE)?
On average, Las Americas Intl. Airport (SDQ) only offers 1 direct flight to Jose Maria Cordova Intl. Airport (MDE) every day. For more choices, try our easy-to-use filter tool. Just enter your details, then click on "1 Stop" or "2+ Stops" to discover flights with layovers.
What are the most popular departure times for flights from Las Americas Intl. Airport (SDQ) to Jose Maria Cordova Intl. Airport (MDE)?
The 6 PM departures from SDQ to MDE are the most sought after. Greater demand means you'll likely pay more for these departures. If you want to save on your trip, choose a less crowded time to fly.
What day of the week has the most flights from SDQ to MDE?
If you travel on a Friday, you'll get the largest range of choices for flights from Las Americas Intl. Airport (SDQ) to Jose Maria Cordova Intl. Airport (MDE).
What is the earliest flight from Las Americas Intl. Airport (SDQ) to Jose Maria Cordova Intl. Airport (MDE)?
Las Americas Intl. Airport (SDQ)'s first flight to Jose Maria Cordova Intl. Airport (MDE) is at approximately 6:06AM UTC-4. With a total flight time of 2h 32m, you'll arrive at around 7:38AM UTC-5.
How long does it take to fly from Las Americas Intl. Airport (SDQ) to Jose Maria Cordova Intl. Airport (MDE)?
It takes approximately 2 hours and 31 minutes to cover the 930 mi from SDQ to MDE.
What airline has the least delays from SDQ to MDE?
Consider traveling with Wingo if you'd like to go straight from Las Americas Intl. Airport (SDQ) to Jose Maria Cordova Intl. Airport (MDE) without any holdups. This airline has the strongest track record for punctuality, with an on-time performance of 88%. Want to get notified of any changes? You can keep an eye on your flight status using the Expedia App.
What is the best time to fly from Las Americas Intl. Airport (SDQ) to Jose Maria Cordova Intl. Airport (MDE)?
To reach Jose Maria Cordova Intl. Airport (MDE) on time, select a flight that leaves from Las Americas Intl. Airport (SDQ) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Medellin from Las Americas Intl. Airport (SDQ)?
Jose Maria Cordova Intl. Airport (MDE) is the only airport in Medellin with direct flights from Las Americas Intl. Airport (SDQ). Check out the options and discover cheap fares on Expedia.
Is it cheaper to buy a plane ticket from Las Americas Intl. Airport (SDQ) to Jose Maria Cordova Intl. Airport (MDE) last-minute?
Booking your ticket from SDQ to MDE just before your trip is usually more expensive. But if there's some wiggle room with your schedule, you could snag a cheap last-minute fare.
Is it cheaper to book a SDQ to MDE flight and hotel package?
Securing a SDQ to MDE flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Pick from our impressive range of stays and then add flights, car rentals and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Las Americas Intl. Airport (SDQ) to Jose Maria Cordova Intl. Airport (MDE)?
Typically, you can cancel or reschedule your SDQ to MDE flight. However, additional fees may apply, especially if you booked more than 24 hours ago. Check your itinerary for the airline's fees and guidelines on flight changes, or if you'd like further details, visit our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.