$212 Cheap Flights from Santo Domingo (SDQ) to Myrtle Beach (MYR)

View $212 flight on Wed, Dec 24, 2025Opens in a new window

Popular airlines from Las Americas Intl. Airport (SDQ) to Myrtle Beach Intl. Airport (MYR)

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Cheap Flights from Santo Domingo to Myrtle Beach (SDQ-MYR)

Prices were available within the past 7 days and start at $212 for one-way flights and $515 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Mon, Oct 27 - Tue, Nov 11
SDQ
Santo Domingo
MYR
Myrtle Beach
$515 Roundtrip, found 1 day ago
$515
Roundtrip
found 1 day ago
Select United flight, departing Mon, Oct 27 from Santo Domingo to Myrtle Beach, returning Tue, Nov 11, priced at $515 found 1 day ago
Delta
Wed, Feb 11 - Tue, Feb 24
SDQ
Santo Domingo
MYR
Myrtle Beach
$516 Roundtrip, found 1 day ago
$516
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Feb 11 from Santo Domingo to Myrtle Beach, returning Tue, Feb 24, priced at $516 found 1 day ago
Delta
Tue, Oct 28 - Mon, Nov 10
SDQ
Santo Domingo
MYR
Myrtle Beach
$519 Roundtrip, found 1 day ago
$519
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Oct 28 from Santo Domingo to Myrtle Beach, returning Mon, Nov 10, priced at $519 found 1 day ago
Delta
Wed, Feb 11 - Mon, Feb 23
SDQ
Santo Domingo
MYR
Myrtle Beach
$521 Roundtrip, found 1 day ago
$521
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Feb 11 from Santo Domingo to Myrtle Beach, returning Mon, Feb 23, priced at $521 found 1 day ago
Spirit Airlines
Thu, Dec 18 - Mon, Jan 5
SDQ
Santo Domingo
MYR
Myrtle Beach
$526 Roundtrip, found 2 hours ago
$526
Roundtrip
found 2 hours ago
Select Spirit Airlines flight, departing Thu, Dec 18 from Santo Domingo to Myrtle Beach, returning Mon, Jan 5, priced at $526 found 2 hours ago
American Airlines
Thu, Dec 18 - Mon, Jan 5
SDQ
Santo Domingo
MYR
Myrtle Beach
$527 Roundtrip, found 2 hours ago
$527
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Thu, Dec 18 from Santo Domingo to Myrtle Beach, returning Mon, Jan 5, priced at $527 found 2 hours ago
American Airlines
Wed, Nov 26 - Sun, Nov 30
SDQ
Santo Domingo
MYR
Myrtle Beach
$527 Roundtrip, found 1 day ago
$527
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Nov 26 from Santo Domingo to Myrtle Beach, returning Sun, Nov 30, priced at $527 found 1 day ago
American Airlines
Thu, Dec 18 - Mon, Jan 5
SDQ
Santo Domingo
MYR
Myrtle Beach
$528 Roundtrip, found 2 hours ago
$528
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Thu, Dec 18 from Santo Domingo to Myrtle Beach, returning Mon, Jan 5, priced at $528 found 2 hours ago
United
Thu, Oct 23 - Tue, Nov 11
SDQ
Santo Domingo
MYR
Myrtle Beach
$530 Roundtrip, found 1 day ago
$530
Roundtrip
found 1 day ago
Select United flight, departing Thu, Oct 23 from Santo Domingo to Myrtle Beach, returning Tue, Nov 11, priced at $530 found 1 day ago
Frontier Airlines
Fri, Sep 26 - Thu, Oct 2
SDQ
Santo Domingo
MYR
Myrtle Beach
$588 Roundtrip, found 3 days ago
$588
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Fri, Sep 26 from Santo Domingo to Myrtle Beach, returning Thu, Oct 2, priced at $588 found 3 days ago

Find the cheapest month to fly from Santo Domingo (SDQ) to Myrtle Beach (MYR)

June is typically the cheapest month to fly

From $314 - $872 per traveler.

Frequently asked questions

How much does a flight from Las Americas Intl. Airport (SDQ) to Myrtle Beach Intl. Airport (MYR) cost?
Secure a cheap one-way flight from $212 or cheap return flight from $515 from Las Americas Intl. Airport (SDQ) to Myrtle Beach Intl. Airport (MYR) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Las Americas Intl. Airport (SDQ) to Myrtle Beach Intl. Airport (MYR)?
October is the cheapest month to fly from SDQ to MYR. Traveling during an off-peak travel window is often the key to landing a great deal.
What is the cheapest airline that flies from Las Americas Intl. Airport (SDQ) to Myrtle Beach Intl. Airport (MYR)?
To find the cheapest airline flying from SDQ to MYR, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Las Americas Intl. Airport (SDQ) to Myrtle Beach Intl. Airport (MYR)?
You'll have to take a flight with a layover if you're traveling from Las Americas Intl. Airport (SDQ) to Myrtle Beach Intl. Airport (MYR). There are no daily direct flights on this route. However, simply filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from SDQ to MYR?
You'll generally find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Las Americas Intl. Airport (SDQ) to Myrtle Beach Intl. Airport (MYR)?
Opt for a flight from Las Americas Intl. Airport (SDQ) to Myrtle Beach Intl. Airport (MYR) that takes off before 3 PM to reduce the risk of cancellations and delays. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Las Americas Intl. Airport (SDQ) to Myrtle Beach Intl. Airport (MYR) last-minute?
Last-minute fares from SDQ to MYR are generally more expensive. For the lowest prices, start searching for flights as early as possible. That said, if you can play around with your travel dates, you may land a cheap ticket right before your journey.
Is it cheaper to book a SDQ to MYR flight and hotel package?
You can save money by securing a SDQ to MYR flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one place. Once you've chosen your preferred accommodations and flights, consider adding extras including tours, car rentals and activities.
Can I cancel or change the date of my flight from Las Americas Intl. Airport (SDQ) to Myrtle Beach Intl. Airport (MYR)?
In most cases, you can cancel or modify your SDQ to MYR flight. However, there may be additional fees, especially if your booking was made more than 24 hours ago. Double-check your itinerary for the airline's policies and fees on flight changes, or if you want further information, head to our Customer Service portal.

Travel information

Travel information

Origin airport
Las Americas Intl.
Destination airport
Myrtle Beach Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Spirit Airlines, United
Roundtrip price
$514
Distance
1198 mi

Book with confidence

Book with confidence

Santo Domingo to Myrtle Beach Flights

The cheapest times to fly from Santo Domingo to Myrtle Beach

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santo Domingo to Myrtle Beach are during the month of October. You can find some of the cheapest flights from Santo Domingo to Myrtle Beach with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santo Domingo to Myrtle Beach

Sunday is one of the best days to book for cheap flights from Santo Domingo to Myrtle Beach: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santo Domingo to Myrtle Beach

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santo Domingo to Myrtle Beach in 2025. You can also book with separate airlines for your outbound and return journeys, from $212 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santo Domingo to Myrtle Beach flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santo Domingo to Myrtle Beach airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santo Domingo to Myrtle Beach Flights

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*Available to One Key members.