$299 Cheap Flights from St. Louis (STL) to Mesa (AZA)

View $299 flight on Sun, Oct 5, 2025Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Phoenix - Mesa Gateway Airport (AZA)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • one key icon

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from St. Louis to Mesa (STL-AZA)

Prices were available within the past 7 days and start at $299 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frequently asked questions

How much does a flight from Lambert-St. Louis Intl. Airport (STL) to Phoenix - Mesa Gateway Airport (AZA) cost?
Secure a cheap one-way flight from $299 or cheap return flight from Lambert-St. Louis Intl. Airport (STL) to Phoenix - Mesa Gateway Airport (AZA) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Lambert-St. Louis Intl. Airport (STL) to Phoenix - Mesa Gateway Airport (AZA)?
Planning your getaway for is a great way to save, as it's the cheapest month for flights between STL and AZA. You'll often find the lowest prices during off-peak months.
What is the cheapest airline that flies from Lambert-St. Louis Intl. Airport (STL) to Phoenix - Mesa Gateway Airport (AZA)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest STL to AZA flight.
How many flights per day from Lambert-St. Louis Intl. Airport (STL) to Phoenix - Mesa Gateway Airport (AZA)?
There are no daily direct flights from Lambert-St. Louis Intl. Airport (STL) to Phoenix - Mesa Gateway Airport (AZA). But you can opt for flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be cruising above the clouds before you know it.
What day of the week has the most flights from STL to AZA?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Keep in mind that flight schedules can change based on various factors, including the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Lambert-St. Louis Intl. Airport (STL) to Phoenix - Mesa Gateway Airport (AZA)?
To land at Phoenix - Mesa Gateway Airport (AZA) on time, book a flight that leaves from Lambert-St. Louis Intl. Airport (STL) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Phoenix from Lambert-St. Louis Intl. Airport (STL)?
If you're boarding a direct flight from Lambert-St. Louis Intl. Airport (STL) to Phoenix, Sky Harbor Intl. Airport (PHX) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Lambert-St. Louis Intl. Airport (STL) to Phoenix - Mesa Gateway Airport (AZA) last-minute?
Waiting until right before your break to book a ticket from STL to AZA often results in higher prices. While you might find some last-minute offers, they're not always guaranteed. Be flexible with your itinerary for the best chance of landing a bargain.
Is it cheaper to book a STL to AZA flight and hotel package?
Booking a STL to AZA flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels in one place. Select from our extensive range of accommodations and then add car rentals, flights and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Lambert-St. Louis Intl. Airport (STL) to Phoenix - Mesa Gateway Airport (AZA)?
In most instances, you're able to cancel or reschedule your STL to AZA flight. However, additional charges may apply, especially if you made your booking more than 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you want further information, go to our Customer Service portal.

Travel information

Travel information

Origin airport
Lambert-St. Louis Intl.
Destination airport
Phoenix - Mesa Gateway
Distance
1244 mi

Book with confidence

Book with confidence

St. Louis to Mesa Flights

The cheapest times to fly from St. Louis to Mesa

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Mesa are during the month of . You can find some of the cheapest flights from St. Louis to Mesa with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to Mesa

Sunday is one of the best days to book for cheap flights from St. Louis to Mesa: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to Mesa

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Mesa in 2025. You can also book with separate airlines for your outbound and return journeys, from $299 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to Mesa flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to Mesa airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

St. Louis to Mesa Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.