$377 Cheap Flights from St. Louis (STL) to São Paulo (GRU)

View $377 flight on Wed, Nov 26, 2025Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to São Paulo/Guarulhos Intl. Airport

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Cheap Flights from St. Louis to São Paulo (STL-GRU)

Prices were available within the past 7 days and start at $377 for one-way flights and $769 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Canada
Tue, Nov 11 - Tue, Dec 9
STL
St. Louis
GRU
Sao Paulo
$769 Roundtrip, found 3 hours ago
$769
Roundtrip
found 3 hours ago
Select Air Canada flight, departing Tue, Nov 11 from St. Louis to Sao Paulo, returning Tue, Dec 9, priced at $769 found 3 hours ago
Air Canada
Thu, Mar 12 - Mon, Mar 23
STL
St. Louis
GRU
Sao Paulo
$775 Roundtrip, found 2 days ago
$775
Roundtrip
found 2 days ago
Select Air Canada flight, departing Thu, Mar 12 from St. Louis to Sao Paulo, returning Mon, Mar 23, priced at $775 found 2 days ago
Air Canada
Wed, Sep 17 - Thu, Sep 25
STL
St. Louis
GRU
Sao Paulo
$837 Roundtrip, found 5 hours ago
$837
Roundtrip
found 5 hours ago
Select Air Canada flight, departing Wed, Sep 17 from St. Louis to Sao Paulo, returning Thu, Sep 25, priced at $837 found 5 hours ago
Air Canada
Wed, Sep 17 - Thu, Sep 25
STL
St. Louis
GRU
Sao Paulo
$844 Roundtrip, found 5 hours ago
$844
Roundtrip
found 5 hours ago
Select Air Canada flight, departing Wed, Sep 17 from St. Louis to Sao Paulo, returning Thu, Sep 25, priced at $844 found 5 hours ago
Air Canada
Wed, Sep 24 - Wed, Oct 1
STL
St. Louis
GRU
Sao Paulo
$849 Roundtrip, found 5 hours ago
$849
Roundtrip
found 5 hours ago
Select Air Canada flight, departing Wed, Sep 24 from St. Louis to Sao Paulo, returning Wed, Oct 1, priced at $849 found 5 hours ago
Air Canada
Fri, Oct 31 - Mon, Nov 3
STL
St. Louis
GRU
Sao Paulo
$851 Roundtrip, found 1 day ago
$851
Roundtrip
found 1 day ago
Select Air Canada flight, departing Fri, Oct 31 from St. Louis to Sao Paulo, returning Mon, Nov 3, priced at $851 found 1 day ago
American Airlines
Tue, Nov 11 - Tue, Dec 9
STL
St. Louis
GRU
Sao Paulo
$855 Roundtrip, found 3 hours ago
$855
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Tue, Nov 11 from St. Louis to Sao Paulo, returning Tue, Dec 9, priced at $855 found 3 hours ago
LATAM Airlines Group
Thu, Mar 12 - Mon, Mar 23
STL
St. Louis
GRU
Sao Paulo
$1,060 Roundtrip, found 2 days ago
$1,060
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Thu, Mar 12 from St. Louis to Sao Paulo, returning Mon, Mar 23, priced at $1,060 found 2 days ago
United
Tue, Dec 16 - Wed, Dec 24
STL
St. Louis
GRU
Sao Paulo
$1,080 Roundtrip, found 1 day ago
$1,080
Roundtrip
found 1 day ago
Select United flight, departing Tue, Dec 16 from St. Louis to Sao Paulo, returning Wed, Dec 24, priced at $1,080 found 1 day ago
Delta
Tue, Nov 11 - Tue, Dec 9
STL
St. Louis
GRU
Sao Paulo
$1,090 Roundtrip, found 3 hours ago
$1,090
Roundtrip
found 3 hours ago
Select Delta flight, departing Tue, Nov 11 from St. Louis to Sao Paulo, returning Tue, Dec 9, priced at $1,090 found 3 hours ago

Alternative airports near São Paulo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Guarulhos - Governor Andre Franco Montoro Intl. GRU. Cheapest option available. Average driving time to city center is 22 minutes. Flights from $1,396
GRU
Guarulhos - Governor Andre Franco Montoro Intl.
Cheapest
Average driving time to city center22 min
Flights from $1,396
Flights from St. Louis (STL) to São Paulo (GRU)
Origin airport
Lambert-St. Louis Intl.
Destination airport
Guarulhos - Governor André Franco Montoro Intl.
Airlines serving
Air Canada, American Airlines, Copa, Delta, GOL Linhas Aereas S.A., LATAM Airlines Group, United, avianca
Roundtrip price
$768
Distance
5148 mi

St. Louis to São Paulo Flights

The cheapest times to fly from St. Louis to São Paulo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to São Paulo are during the month of November. You can find some of the cheapest flights from St. Louis to São Paulo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to São Paulo

Sunday is one of the best days to book for cheap flights from St. Louis to São Paulo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to São Paulo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to São Paulo in 2025. You can also book with separate airlines for your outbound and return journeys, from $377 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to São Paulo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to São Paulo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Lambert-St. Louis Intl. Airport (STL) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) cost?
Grab a cheap one-way flight from $377 or cheap return flight from $769 from Lambert-St. Louis Intl. Airport (STL) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Lambert-St. Louis Intl. Airport (STL) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
November is the least expensive month to fly from STL to GRU. Traveling outside of peak seasons is often the key to finding better fares.
What is the cheapest airline that flies from Lambert-St. Louis Intl. Airport (STL) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
Expedia's filter tool lets you easily compare different airlines, departure times and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest STL to GRU flight.
How many flights per day from Lambert-St. Louis Intl. Airport (STL) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
Nonstop flights from Lambert-St. Louis Intl. Airport (STL) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your travel details and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from STL to GRU?
Typically you'll find the greatest selection of flight options on a Friday. Tuesdays tend to be the quietest.* But this can vary based on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Lambert-St. Louis Intl. Airport (STL) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
To avoid possible delays on the Lambert-St. Louis Intl. Airport (STL) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) route, fly before 3 PM. Flights after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Lambert-St. Louis Intl. Airport (STL) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) last-minute?
Booking your flight from STL to GRU just before your getaway is typically more expensive. But if there's some wiggle room with your itinerary, you could score a cheap last-minute fare.
Is it cheaper to book a STL to GRU flight and hotel package?
Opting for a STL to GRU flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our wide range of accommodations and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Lambert-St. Louis Intl. Airport (STL) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
Typically, you're able to cancel or reschedule your STL to GRU flight. However, there may be additional fees, especially if your booking was made over 24 hours ago. Double-check your itinerary for the airline's policies and fees on flight changes, or if you want further details, go to our Customer Service portal.

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*Available to One Key members.