$221 Cheap Flights from Tallahassee (TLH) to Panama City (PTY)

View $221 flight on Wed, Dec 10, 2025Opens in a new window

Popular airlines from Tallahassee Intl. Airport (TLH) to Tocumen Intl. Airport (PTY)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • one key icon

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Tallahassee to Panama City (TLH-PTY)

Prices were available within the past 7 days and start at $221 for one-way flights and $467 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Oct 1 - Wed, Apr 1
TLH
Tallahassee
PTY
Panama City
$467 Roundtrip, found 14 hours ago
$467
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Wed, Oct 1 from Tallahassee to Panama City, returning Wed, Apr 1, priced at $467 found 14 hours ago
Delta
Wed, Oct 29 - Wed, Nov 12
TLH
Tallahassee
PTY
Panama City
$474 Roundtrip, found 20 hours ago
$474
Roundtrip
found 20 hours ago
Select Delta flight, departing Wed, Oct 29 from Tallahassee to Panama City, returning Wed, Nov 12, priced at $474 found 20 hours ago
American Airlines
Wed, Oct 1 - Wed, Apr 1
TLH
Tallahassee
PTY
Panama City
$476 Roundtrip, found 14 hours ago
$476
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Wed, Oct 1 from Tallahassee to Panama City, returning Wed, Apr 1, priced at $476 found 14 hours ago
Delta
Wed, Oct 29 - Wed, Nov 12
TLH
Tallahassee
PTY
Panama City
$481 Roundtrip, found 20 hours ago
$481
Roundtrip
found 20 hours ago
Select Delta flight, departing Wed, Oct 29 from Tallahassee to Panama City, returning Wed, Nov 12, priced at $481 found 20 hours ago
American Airlines
Wed, Oct 1 - Wed, Apr 1
TLH
Tallahassee
PTY
Panama City
$484 Roundtrip, found 14 hours ago
$484
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Wed, Oct 1 from Tallahassee to Panama City, returning Wed, Apr 1, priced at $484 found 14 hours ago
American Airlines
Thu, Feb 5 - Tue, Feb 10
TLH
Tallahassee
PTY
Panama City
$487 Roundtrip, found 5 hours ago
$487
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Thu, Feb 5 from Tallahassee to Panama City, returning Tue, Feb 10, priced at $487 found 5 hours ago
Delta
Fri, Feb 6 - Tue, Feb 10
TLH
Tallahassee
PTY
Panama City
$494 Roundtrip, found 16 hours ago
$494
Roundtrip
found 16 hours ago
Select Delta flight, departing Fri, Feb 6 from Tallahassee to Panama City, returning Tue, Feb 10, priced at $494 found 16 hours ago
American Airlines
Fri, Feb 6 - Tue, Feb 10
TLH
Tallahassee
PTY
Panama City
$496 Roundtrip, found 16 hours ago
$496
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Fri, Feb 6 from Tallahassee to Panama City, returning Tue, Feb 10, priced at $496 found 16 hours ago
American Airlines
Thu, Feb 5 - Tue, Feb 10
TLH
Tallahassee
PTY
Panama City
$496 Roundtrip, found 5 hours ago
$496
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Thu, Feb 5 from Tallahassee to Panama City, returning Tue, Feb 10, priced at $496 found 5 hours ago
Delta
Thu, Feb 5 - Tue, Feb 10
TLH
Tallahassee
PTY
Panama City
$501 Roundtrip, found 5 hours ago
$501
Roundtrip
found 5 hours ago
Select Delta flight, departing Thu, Feb 5 from Tallahassee to Panama City, returning Tue, Feb 10, priced at $501 found 5 hours ago

Find the cheapest month to fly from Tallahassee (TLH) to Panama City (PTY)

August is typically the cheapest month to fly

From $337 - $1,051 per traveler.

Graph displaying average flight prices per month

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $642
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $642
Flights from Tallahassee (TLH) to Panama City (PTY)
Origin airport
Tallahassee Intl.
Destination airport
Tocumen Intl.
Airlines serving
American Airlines, Delta
Roundtrip price
$467
Distance
1507 mi

Tallahassee to Panama City Flights

The cheapest times to fly from Tallahassee to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Tallahassee to Panama City are during the month of October. You can find some of the cheapest flights from Tallahassee to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Tallahassee to Panama City

Sunday is one of the best days to book for cheap flights from Tallahassee to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Tallahassee to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Tallahassee to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $221 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Tallahassee to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Tallahassee to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Tallahassee Intl. Airport (TLH) to Tocumen Intl. Airport (PTY) cost?
Discover the latest flight deals from TLH to PTY by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from TLH to PTY?
The cheapest flights from TLH to PTY are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from TLH to PTY?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from TLH to PTY. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Tallahassee Intl. Airport (TLH) to Tocumen Intl. Airport (PTY)?
There are no daily direct flights from Tallahassee Intl. Airport (TLH) to Tocumen Intl. Airport (PTY). But you can choose flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be cruising above the clouds in no time at all.
What day of the week has the most flights from TLH to PTY?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can change depending on a range of factors, such as the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tallahassee Intl. Airport (TLH) to Tocumen Intl. Airport (PTY)?
Select a flight from Tallahassee Intl. Airport (TLH) to Tocumen Intl. Airport (PTY) that leaves before 3 PM to reduce the risk of cancellations. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Tallahassee Intl. Airport (TLH) to Tocumen Intl. Airport (PTY) last-minute?
Last-minute fares from TLH to PTY are typically more expensive. To lock in the lowest prices, start searching for flights early. That said, if your travel plans are flexible, it's possible to find a cheap fare right before your journey.
Is it cheaper to book a TLH to PTY flight and hotel package?
Compared with arranging flights and hotels separately, booking a TLH to PTY flight and hotel package with Expedia could result in significant savings. Better still, managing everything in one place takes the hassle out of planning your trip. Simply secure your flights and choose from our wide range of hotels, then tailor your trip with other add-ons like car rentals and activities.
Can I cancel or change the date of my flight from Tallahassee Intl. Airport (TLH) to Tocumen Intl. Airport (PTY)?
Typically, it's possible to cancel or reschedule your TLH to PTY flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more information on our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.