$134 Cheap Flights from Knoxville (TYS) to Seattle (SEA)

Knoxville (TYS) to Seattle (SEA) at a glance

Travel to Seattle (SEA) from Knoxville (TYS) with a selection of airlines offering domestic long-haul flights. You can choose between full-service and low-cost carriers, allowing you to find the best option that suits your budget and travel schedule. As you plan your journey from Knoxville to Seattle, consider the various itineraries available to explore the city's iconic attractions and vibrant neighborhoods. Discover all the essential details for flights from McGhee Tyson Airport to Seattle-Tacoma International Airport.

• Fastest flight duration: around 6h 45m in-flight, plus roughly 1h 15m layover with one stop
• Route distance: roughly 2,100 miles (3,380 km)
• Flights per week: around 15+ flights with multiple daily departures on average
• Typical fares (one-way): economy tickets often range from $155–$510, depending on seasonality and how far ahead you book

Flights from McGhee Tyson Airport (TYS) to Seattle - Tacoma International Airport (SEA)

Based on recent traveler bookings, here are the top airlines flying from Knoxville to Seattle, often selected for their one-stop services. Popular layover options include O'Hare International Airport (ORD) with about a 1 hour and 15-minute stop, Dallas-Fort Worth International Airport (DFW) also around 1 hour and 15 minutes, and Hartsfield-Jackson Atlanta International Airport (ATL) with a similar layover time. These choices offer the flexibility to balance price, total travel time, and cabin class for your ideal itinerary.

• American Airlines: This major carrier provides one-stop flights, with one-way ticket prices generally falling between $155 and $560. It represents around 45% of the departures for this route, with a flight duration of 6 hours and 45 minutes, leading to a total travel time of approximately 8 hours, including layover time.
• United: Serving the route with one-stop options, United Airlines features one-way fares that usually range from $205 to $685. It accounts for about 27% of the departures, offering a flight time of 6 hours and 45 minutes, resulting in an overall journey time close to 8 hours, factoring in layovers.
• Delta: Delta Airlines also offers one-stop service, with one-way fares typically priced between $185 and $650. It comprises roughly 23% of the departures on this route, with an in-flight duration of 6 hours and 45 minutes and a total travel time nearing 8 hours, including any layover.
• Alaska Airlines: This full-service airline provides one-stop service with one-way fares that typically range from $260 to $540. It makes up about 3% of the departures on this route, featuring a flight time of 6 hours and 45 minutes and an overall journey time of around 8 hours, including layovers.
• Frontier Airlines: As a low-cost option, Frontier offers one-stop flights with one-way fares ranging from $155 to $305. It constitutes approximately 2% of the departures for this route, with a flying time of 6 hours and 45 minutes and a total travel duration of about 8 hours, including layover periods.

Travelers have the option to enhance their journey from Knoxville to Seattle with upgraded flight choices. United Airlines offers first class, while Delta provides both first class and premium economy cabins. American Airlines also features first class for a more comfortable experience.

Best time to fly from Knoxville (TYS) to Seattle (SEA)

The most popular months for travelers flying from Knoxville to Seattle are April, July, and August, when peak temperatures in Seattle reach up to 67.5°F in August. If you prefer quieter travel, consider February, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 40.5°F. For better deals, September usually offers the lowest average one-way fare around $289. Flight availability peaks in August, with approximately 19 flights per week, making it easier to find convenient departure times.

• Cheapest time to fly: September usually offers good deals with average one-way fare around $289, roughly 15% cheaper than the yearly average.
• Another budget-friendly time to fly: October typically offers an average one-way fare of around $320.
• Most flight options: August has the highest number of flights from Knoxville to Seattle, with approximately 19 flights per week, giving you more flexibility in scheduling your trip.

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative route from Knoxville (TYS) to Seattle (SEA)

• Chattanooga to Seattle (CHA-SEA): Chattanooga Metropolitan Airport (CHA) is located approximately 86 miles from McGhee Tyson Airport (TYS). One-way economy prices for this route usually fall between $100 and $465, influenced by the time of year and how far in advance you book. Flights on this route often include both one-stop and multi-stop options, with common layover points at O'Hare International Airport (ORD) and Dallas-Fort Worth International Airport (DFW). Major airlines operating this route include American Airlines and Delta, with first-class service also available.

How to find the best prices for flights from Knoxville (TYS) to Seattle (SEA)

Getting some of the best deals on flights from Knoxville to Seattle is all about timing and flexibility. Here are some key tips to help you save:

1. Best times to book and fly: cheaper fares are typically found when booking 2-8 weeks in advance, which aligns with when most travelers make their reservations. Evening departures from 6 PM to 12 AM tend to be less expensive, whereas morning flights from 5 AM to 12 PM are the most popular. Additionally, flying on Thursday offers both lower prices and increased popularity among travelers.
2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Seattle - Tacoma International Airport from McGhee Tyson Airport

Seattle welcomes travelers from Knoxville with a range of transport options based on price, convenience, and proximity. For departures, McGhee Tyson Airport is roughly a 20-minute drive (covering about 15 miles) from central Knoxville. Seattle city center is approximately a 20-minute drive (covering about 14 miles) from Seattle - Tacoma International Airport, depending on traffic. Here's how to reach Seattle efficiently:

• Hotel transfer: Transfers offer a convenient way to reach your hotel in Seattle, with private rides that can be arranged in advance.
• Car rental: Renting a car from Seattle - Tacoma International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Seattle - Tacoma International Airport on Expedia.
• Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
• Public transportation: From Seattle - Tacoma International Airport, SeaTac/Airport Station, a metro station, is located about 0.3 miles away on foot, while Tukwila Station, a train station, is about 4.3 miles away by car, providing convenient access for travelers to various destinations.

Knoxville to Seattle Flights

The cheapest times to fly from Knoxville to Seattle

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Seattle are during the month of December. You can find some of the cheapest flights from Knoxville to Seattle with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Knoxville to Seattle

Sunday is one of the best days to book for cheap flights from Knoxville to Seattle: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Knoxville to Seattle

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Seattle in 2026. You can also book with separate airlines for your outbound and return journeys, from $134 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Seattle flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Seattle airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.