Los Santos Vacations & Trips from $699

Book a Hotel + Flight or Car together to unlock savings

Choose one or more items to build your trip:

Your Los Santos Vacation

Head off on your next exciting adventure with a Los Santos vacation package, and leave relaxed knowing all the details are taken care of. And with the ability to customize your getaway, it'll be one to remember! Planning an itinerary for your trip to Los Santos? Make a start with cities like Las Tablas, Pedasi and Punta Mala. Expedia is a one-stop shop when it comes to planning your Los Santos vacation. From flights and accommodations, to rental cars and activities, we're here to help you curate a travel experience like no other.

Top destinations in Los Santos

Mil Polleras Festival! #lifeatexpedia
FlightsFlightsHotelsHotels

Las Tablas

Las Tablas

The Latest Los Santos Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
per person
Jul 12 - Jul 17
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
9/10 Wonderful! (2,402 reviews)
very close to everything!! very good value for money

Reviewed on May 29, 2024

Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
Save 100% on your flight
per person
Jul 12 - Jul 17
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
7.4/10 Good! (973 reviews)
The property is fine, but it does not have a 5stars category. The food at the lunch buffet was terrible. There mosquitoes and others bugs were insane. I could understand that is tropical environment, but cleaning and fumigation will improve the situation. We came back with hundreds of mosquito's bites

Reviewed on May 29, 2024

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
per person
Aug 6 - Aug 9
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
9/10 Wonderful! (682 reviews)
Best place to stay in the old town.

Reviewed on May 21, 2024

Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
per person
Jul 17 - Jul 23
found 3 hours ago
Roundtrip flight included
Newark (EWR) to Panama City (PTY)
9.8/10 Exceptional! (48 reviews)
Wonderful stay! The hosts took very good care of us ! The french breakfast was very delicious.Close to playa Clara and restaurants.We will be back.Un gros merci!

Reviewed on Dec 17, 2023

La Coralina Island House

La Coralina Island House

3.5 out of 5
per person
Jul 8 - Jul 11
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
9.4/10 Exceptional! (44 reviews)
Very difficult to get around because of the only unpaved road. The resort was fine. If you go there, plan on staying 3-4 days because it’s very hard to get to due to the only bumpy road.

Reviewed on May 17, 2024

Los Santos Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)
Top Sights
Venao Beach, El Uverito Beach and Playa El Toro

Los Santos Hotel Deals

Selina Playa Venao - Hostel
Selina Playa Venao - Hostel
3 out of 5
Playa Venao 1, Azurero District, Las Escobas del Venado, Los Santos
Fully refundableReserve now, pay when you stay
The price is $48 per night from Jun 11 to Jun 12
$48
$53 total
includes taxes & fees
Jun 11 - Jun 12
7.8/10 Good! (93 reviews)
"Really good place. Warm water, near the beach, beautiful place. The only downside is that we got a dirty towel in the room and that they don’t give towels for the beach."

Reviewed on Dec 5, 2023

Selina Playa Venao - Hostel
Selina River Venao
Selina River Venao
3 out of 5
Belisario Porras Avenue, Playa Venao, Las Escobas del Venado, Provincia de Herrera
Fully refundableReserve now, pay when you stay
The price is $41 per night from Jun 11 to Jun 12
$41
$46 total
includes taxes & fees
Jun 11 - Jun 12
8.2/10 Very Good! (12 reviews)
This is the spot in Venao
"Just amazing, super friendly staff."

Reviewed on Mar 6, 2024

Selina River Venao
Casa Lajagua
Casa Lajagua
3 out of 5
Calle principal de Pedasi, Pedasi, Panama
The price is $85 per night from May 31 to Jun 1
$85
$94 total
includes taxes & fees
May 31 - Jun 1
9/10 Wonderful! (64 reviews)
Fantastic place to stay
"My wife and I stayed at Casa Lajagua March 4 - Mar 7 and had a very enjoyable stay. The rooms had air-conditioning, shower had hot water and the rooms were spacious and clean. One great thing was that the rooms did not have TV's, it was so nice to get away from all the stuff that was going on back ..."

Reviewed on Mar 27, 2024

Casa Lajagua
See all 321 properties in Los Santos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Kid Friendly Vacations

Kid Friendly Vacations

Frequently asked questions

How much does a Los Santos vacation package cost?
The most affordable Los Santos vacation package is $699, so your dream escape can become a reality — without burning a hole in your pocket. Combine flights, hotels, car rentals and more to create a package that fits you.
How do I get a cheap travel package to Los Santos?
You’ll save loads of cash if you bundle your car rentals, hotels and flights into a Los Santos travel package. Sometimes cheap means fewer choices. But that’s not the case with Expedia. We offer over 550 air carriers and 1,000,000 properties worldwide, so you’ll always have plenty of options to choose from. Like to save even more? Add some exciting activities to your package deal to unlock even bigger bargains! After all, travel is about more than simply getting to your destination.
What are the top hotels in Los Santos?
For properties in Las Escobas del Venado with friendly service and cozy beds, you can’t beat Villa Marina Lodge And Condos and Hotel Presidente. If you plan to visit Pedasi as well, you can look forward to a good night’s sleep at Casa Lajagua or Hotel El Sitio Playa Venao.
How far in advance should I book my Los Santos vacation?
It all depends on the airline, but you can usually look up international flights on Expedia nearly a year in advance. While it’s advisable to book ahead of time, lucky travelers will occasionally score a cheaper seat just weeks before their intended journey.
What does an Expedia Los Santos travel package include?
It all depends on what type of getaway you want to have. Los Santos vacation deals can include car rentals, hotels and flights. You can mix and match to create the package that suits your needs. You can also add on activities and experiences after you’ve booked to land even bigger discounts.
What should I know before booking a Los Santos travel package?
You’ll pick up big savings when you bundle your flights, hotels and rental cars into a package. Plus, booking everything in one place makes trip planning much easier. So why waste your time or money? Whether you’re organizing a luxury romantic escape or a low-cost family break, browse our vacation packages today.
Can I choose my airline with a Los Santos Expedia vacation package?
Most definitely. Expedia has more than 550 partner airlines to pick from around the world. With all that choice at your fingertips, finding the perfect carrier to whisk you off to Los Santos won’t be difficult.
If I'm not able to travel, can I cancel my Los Santos vacation package?
Your situation can change in a flash, so yes, you can. You may be able to cancel or alter your Los Santos vacation package at no cost if you’ve booked in the last 24 hours. For bookings made more than 24 hours ago, you can still make changes, but your airline, hotel or car rental company may charge additional fees. Want more information? Have a look at our Customer Service Portal. We’ll help make sure your trip goes off without a hitch.

Discover the most popular places to visit in Los Santos

Image for Los Destiladeros Beach

Los Destiladeros Beach

4/5(8 reviews)

If a restful vacation is part of your travel plans, Los Destiladeros Beach might be the perfect place to seek out during your trip to Punta Mala.

Los Destiladeros Beach
Image for Playa El Arenal

Playa El Arenal

4/5(7 reviews)

If a restful vacation is part of your travel plans, Playa El Arenal might be the perfect place to seek out during your trip to Pedasi.

Playa El Arenal
Image for Los Buzos Beach

Los Buzos Beach

5/5(1 review)

If a restful vacation is part of your travel plans, Los Buzos Beach might be the perfect place to seek out during your trip to Cambutal.

Los Buzos Beach

Other vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.