Find hotels in Santa Clara, Panama City from $48

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Discover 1,272 Santa Clara hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Crowne Plaza Panama Airport, an IHG Hotel
Outdoor pool, pool umbrellas, sun loungers
Crowne Plaza Panama Airport, an IHG Hotel
4.0 star property
8.4 out of 10, Very Good, 1,862 reviews
"Great staff and hotel, please fix the hot water "
The price is $112
$123 total
includes taxes & fees
Jun 16 - Jun 17
Crowne Plaza Panama Airport, an IHG Hotel
Riande Aeropuerto Hotel & Casino
Outdoor pool, free cabanas, pool umbrellas
Riande Aeropuerto Hotel & Casino
4.0 star property
8.2 out of 10, Very Good, 1,578 reviews
"Liked the fact that there is transportation from the airport and to the airport almost the 24hr of the day"
The price is $97
$107 total
includes taxes & fees
Jun 19 - Jun 20
Riande Aeropuerto Hotel & Casino
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Outdoor pool, free cabanas, pool umbrellas
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
9.6 out of 10, Exceptional, 472 reviews
"Personal muy amable"
The price is $254
$280 total
includes taxes & fees
Jun 16 - Jun 17
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
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Courtyard by Marriott Panama Metromall
Lobby
Courtyard by Marriott Panama Metromall
4.0 star property
8.8 out of 10, Excellent, 910 reviews
"Had everything I needed. Gym is good to workout in. The stay would have been better if there was room service but it was not being offered at the time"
The price is $125
$218 total
includes taxes & fees
Jun 12 - Jun 13
Courtyard by Marriott Panama Metromall
The Westin Panama
Outdoor pool, pool umbrellas, sun loungers
The Westin Panama
4.0 star property
8.8 out of 10, Excellent, 220 reviews
"Great business stay. "
The price is $195
$214 total
includes taxes & fees
Jun 21 - Jun 22
The Westin Panama
Express Inn Panama International Airport Hostel
Front of property
Express Inn Panama International Airport Hostel
1.5 star property
5.6 out of 10, 485 reviews
" close to the airport 12min walking.... nice"
The price is $55
$73 total
includes taxes & fees
Jun 6 - Jun 7
Express Inn Panama International Airport Hostel
B&B Lodgings
Laptop workspace, soundproofing, free WiFi, bed sheets
B&B Lodgings
2.5 star property
7.8 out of 10, Good, 57 reviews
"The facility provides transportation to go for shopping, provides drinking water "
The price is $48
$53 total
includes taxes & fees
Jun 6 - Jun 7
B&B Lodgings
Luxury Apartment With Private Beach And Sea View
Pool
Luxury Apartment With Private Beach And Sea View
9.8 out of 10, Exceptional, 6 reviews
"The property was indeed luxurious! So happy we had a full kitchen and a rental car. Although, the property had several restaurants they were expensive. It’s ok to an occasional meal. We couldn’t imagine total dining prices without a kitchen. The pools and salsa classes were fun. Everything is approximately 20-25 distance including airport; Toucman PYL. Taxis and Huber is not too expensive. Panama Canal was a lovely excursion. Downtown center is beautiful, be mindful of surroundings areas...
Luxury Apartment With Private Beach And Sea View
La Semilla Ecolodge
Outdoor pool
La Semilla Ecolodge
3.5 star property
7.8 out of 10, Good, 11 reviews
"David the manager welcomed us, he and his staff were very attentive the whole stay, and informative about the wildlife. Watching the birds was very relaxing, and the bonus was a Sloth sighting. Unfortunately we had rain for a day so that cramped the exploring abit. Kayaking on the nearby lake was peaceful"
The price is $115
$127 total
includes taxes & fees
Jun 6 - Jun 7
La Semilla Ecolodge
Apartamento a 10 minutos del aeropuerto
Property grounds
Apartamento a 10 minutos del aeropuerto
The price is $48
$83 total
includes taxes & fees
Jun 9 - Jun 10
Apartamento a 10 minutos del aeropuerto
Casa de Campo / E C O Aventura / Clima 18 a 25
Property grounds
Casa de Campo / E C O Aventura / Clima 18 a 25
The price is $325
$404 total
includes taxes & fees
Jun 6 - Jun 7
Casa de Campo / E C O Aventura / Clima 18 a 25
HOUSE IN LAS ACACIAS
Property grounds
HOUSE IN LAS ACACIAS
The price is $200
$258 total
includes taxes & fees
Jun 6 - Jun 7
HOUSE IN LAS ACACIAS
2Bed Apt in Panama City - Costa del este with Ocean View
Property grounds
2Bed Apt in Panama City - Costa del este with Ocean View
8.0 out of 10, Very Good, 5 reviews
"We had an excellent stay at this property. Spacious, beautiful views and attentive host. The check-in process was smooth and the host was very timely with meeting us. Also, there was an issue with one of the A/C units during out stay and the host addressed it immediately! We had to extend a few times waiting on lost travel documents and were accommodated without issue. We would definitely stay here again, as well as other properties that are hosted by Tony. One caution, which Tony pointed out...
2Bed Apt in Panama City - Costa del este with Ocean View
Cozy and quiet apartment: 2 bedrooms 2 bathrooms and balcony.
Fridge, microwave, oven, coffee/tea maker
Cozy and quiet apartment: 2 bedrooms 2 bathrooms and balcony.
Cozy and quiet apartment: 2 bedrooms 2 bathrooms and balcony.
SILENT COUNTRYSIDE IN THE HEART OF PANAMA AREA
TV, books
SILENT COUNTRYSIDE IN THE HEART OF PANAMA AREA
SILENT COUNTRYSIDE IN THE HEART OF PANAMA AREA
Exclusive Villa with panoramic vistas of city and mountains from your own hottub
Outdoor pool, a heated pool
Exclusive Villa with panoramic vistas of city and mountains from your own hottub
10.0 out of 10, Exceptional, 1 review
"Great house and property manager in a beautiful spot. We didn’t want to leave."
Exclusive Villa with panoramic vistas of city and mountains from your own hottub
18G Oceanview Luxury Apt with Rooftop Pool
Pool
18G Oceanview Luxury Apt with Rooftop Pool
18G Oceanview Luxury Apt with Rooftop Pool
Rent a room or a house at the beach in Punta Chame
Property grounds
Rent a room or a house at the beach in Punta Chame
2.0 out of 10, 1 review
"After renting the entire property with the confirmation that it would be just my family in the house and on the 2 acre grounds- The owner omitted that she lives at the property with her five dogs, that are inside and outside dogs. No security for your stuff once in the house, no locks on the bedroom doors. Owner had invited over a dozen of her personal friends to celebrate the New Year- she had done this without our knowledge. She then sublet the guest cottage while we were still renting the...
Rent a room or a house at the beach in Punta Chame
Modern Apartment in Costa del Este
Terrace/patio
Modern Apartment in Costa del Este
3.5 star property
Modern Apartment in Costa del Este
Alojamiento con Vistas Costa del Este
Fridge, microwave, oven, coffee/tea maker
Alojamiento con Vistas Costa del Este
Alojamiento con Vistas Costa del Este
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See all available properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Santa Clara

Hotels in top Panama City neighborhoods Learn more about Santa Clara
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Casco Viejo

4.5/5(178 area reviews)

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or National Theater while you're exploring the area.

Find hotels in Casco Viejo

Frequently asked questions

What is Santa Clara like?

Travelers will be sure to find plenty to entertain them in Panama City's Santa Clara neighborhood.

If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?

Yes! You'll find that most hotel reservations are refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to review the best options available in Santa Clara.

Where can I learn more about changing or cancelling my trip to Santa Clara?

To access more information about picking new dates or cancelling your trip to Santa Clara, go to https://www.expedia.com/service/.

What are the top things to see and do in Santa Clara?

A few places to visit in the area around Santa Clara include Estadio Rommel Fernandez, Plaza de Francia, and Atrio Mall. While you're out sightseeing, Monte Oscuro and Los Pueblos Commercial Center are a couple of additional sights to visit in Panama City.

Recent reviews of Santa Clara hotels

TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro

5/5 Excellent
"This was an amazing stay, the property is in great shape, there are many amenities around the area, you can walk to just about anything (dinning, shopping and etc.) in a matter of minutes. I highly recommend this hotel."
A verified traveler from Pinellas Park stayed at TRYP by Wyndham Panamá Centro
Posted 16 hours ago
TRYP by Wyndham Panamá Centro