Midtown, MO
![Midtown](https://mediaim.expedia.com/destination/9/8b783ab839a2184e9ca1c96805126ab3.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)
Popular places to visit
St. Louis University
Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.
Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you spend time at Scott Joplin House State Historic Site. Experience the area's great live music or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
Things to do
The Dinner Detective Murder Mystery Dinner Show - St. Louis, MO
Explore St. Louis with a Unique Scavenger Hunt by Operation City Quest
Midtown Hotel Deals
![Residence Inn by Marriott St Louis Downtown](https://images.trvl-media.com/lodging/2000000/1280000/1273600/1273566/a7e6efee_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Reviewed on Jun 18, 2024
![Element St. Louis Midtown](https://images.trvl-media.com/lodging/58000000/57060000/57057200/57057177/6ae0e8f9_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Reviewed on Jun 11, 2024
![Hyatt Regency St. Louis at The Arch](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/54a421cf_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Reviewed on Jun 16, 2024
![Hollywood Casino & Hotel St. Louis](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/7188325f_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Reviewed on Jun 17, 2024
![Clayton Plaza Hotel & Extended Stay](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/b3c5d3cd_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Reviewed on Jun 18, 2024
![Drury Plaza Hotel St. Louis at the Arch](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/56fc52a7_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Reviewed on Jun 18, 2024
Other neighborhoods around Midtown
![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium)
The Gate
While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Enterprise Center.
![St. Louis which includes interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/21000/21573-Saint-Louis.jpg?impolicy=fcrop&w=350&h=192&q=medium)
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and Enterprise Center are top sights worth seeing.
![Lafayette Square which includes a house and a garden](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/199000/199627-Saint-Louis.jpg?impolicy=fcrop&w=350&h=192&q=medium)
Lafayette Square
The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Enterprise Center, a few notable attractions nearby.
![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium)
Shaw
While there might not be top attractions in Shaw, you can explore the larger area and discover places like Missouri Botanical Gardens and Arboretum and Tower Grove Park.
![Central West End](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/199000/199931-Central-West-End.jpg?impolicy=fcrop&w=350&h=192&q=medium)
Central West End
The ample dining options and lush forests are just a few popular features of the neighborhood. Make a stop by Cathedral Basilica of St. Louis or World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
![Not just bars but also loft apartments are lit in rainbow lights for Pride weekend in the Grove neighborhood in St. Louis! #LifeAtExpedia](https://mediaim.expedia.com/destination/2/a89c7dead6cca8d1edf30903beaa32df.jpg?impolicy=fcrop&w=350&h=192&q=medium)
The Grove
The Grove might not have many top sights, but St. Louis Zoo and St. Louis Science Center are two attractions nearby that you can check out.
More to Explore
St. Louis Vacation Ideas for Planning an Itinerary
- St. Louis University
- Chaifetz Arena
- Scott Joplin House State Historic Site
- Museum of Contemporary Religious Art
- Samuel Cupples House
- Enterprise Center
- Busch Stadium
- St. Louis Union Station
- St. Louis Zoo
- Gateway Arch
- Washington University in St. Louis
- Forest Park
- Hollywood Casino Amphitheatre
- City Museum
- Dome at America’s Center
- Ameristar Casino St. Charles
- Barnes Jewish Hospital
- America's Center Convention Complex
- Mississippi River
- Magic House - St. Louis Children's Museum
- Fox Theater
- Missouri Botanical Gardens and Arboretum
- Horseshoe St. Louis Casino
- Westport Plaza
- Saint Louis Galleria Mall
- Hollywood Casino
- Lindenwood University
- Missouri River
- St. Louis Aquarium at Union Station
- St Charles Convention Center
- Historic Main Street
- Anheuser-Busch Brewery