$257 Cheap Flights from Mexico City (MEX) to Santiago (SCL)

Bundle Your Flight + Hotel & Save!

Featured airlines

Top nine airline logos for desktop

Cheap Flights from Mexico City to Santiago (MEX-SCL)

Prices were available within the past 7 days and start at $257 for one-way flights and $473 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Sat, Jun 8 - Mon, Jun 10
NLU
Santa Lucía
SCL
Santiago
$473 Roundtrip, found 2 days ago
$473
Roundtrip
found 2 days ago
Select Copa flight, departing Sat, Jun 8 from Santa Lucía to Santiago, returning Mon, Jun 10, priced at $473 found 2 days ago
Arajet
Tue, Jun 25 - Fri, Jul 12
NLU
Santa Lucía
SCL
Santiago
$476 Roundtrip, found 4 days ago
$476
Roundtrip
found 4 days ago
Select Arajet flight, departing Tue, Jun 25 from Santa Lucía to Santiago, returning Fri, Jul 12, priced at $476 found 4 days ago
Arajet
Thu, Sep 12 - Mon, Sep 23
NLU
Santa Lucía
SCL
Santiago
$477 Roundtrip, found 6 days ago
$477
Roundtrip
found 6 days ago
Select Arajet flight, departing Thu, Sep 12 from Santa Lucía to Santiago, returning Mon, Sep 23, priced at $477 found 6 days ago
Arajet
Sun, Sep 1 - Mon, Sep 9
NLU
Santa Lucía
SCL
Santiago
$490 Roundtrip, found 3 days ago
$490
Roundtrip
found 3 days ago
Select Arajet flight, departing Sun, Sep 1 from Santa Lucía to Santiago, returning Mon, Sep 9, priced at $490 found 3 days ago
Arajet
Thu, Mar 20 - Fri, Mar 28
NLU
Santa Lucía
SCL
Santiago
$496 Roundtrip, found 1 day ago
$496
Roundtrip
found 1 day ago
Select Arajet flight, departing Thu, Mar 20 from Santa Lucía to Santiago, returning Fri, Mar 28, priced at $496 found 1 day ago
Arajet
Thu, Mar 20 - Fri, Mar 28
NLU
Santa Lucía
SCL
Santiago
$497 Roundtrip, found 1 day ago
$497
Roundtrip
found 1 day ago
Select Arajet flight, departing Thu, Mar 20 from Santa Lucía to Santiago, returning Fri, Mar 28, priced at $497 found 1 day ago
Arajet
Tue, Sep 17 - Wed, Sep 25
NLU
Santa Lucía
SCL
Santiago
$499 Roundtrip, found 3 days ago
$499
Roundtrip
found 3 days ago
Select Arajet flight, departing Tue, Sep 17 from Santa Lucía to Santiago, returning Wed, Sep 25, priced at $499 found 3 days ago
Arajet
Tue, Sep 17 - Wed, Sep 25
NLU
Santa Lucía
SCL
Santiago
$501 Roundtrip, found 3 days ago
$501
Roundtrip
found 3 days ago
Select Arajet flight, departing Tue, Sep 17 from Santa Lucía to Santiago, returning Wed, Sep 25, priced at $501 found 3 days ago
Copa
Tue, Aug 27 - Fri, Sep 6
MEX
Mexico City
SCL
Santiago
$505 Roundtrip, found 1 day ago
$505
Roundtrip
found 1 day ago
Select Copa flight, departing Tue, Aug 27 from Mexico City to Santiago, returning Fri, Sep 6, priced at $505 found 1 day ago
avianca
Tue, Feb 4 - Tue, Feb 11
MEX
Mexico City
SCL
Santiago
$551 Roundtrip, found 6 hours ago
$551
Roundtrip
found 6 hours ago
Select avianca flight, departing Tue, Feb 4 from Mexico City to Santiago, returning Tue, Feb 11, priced at $551 found 6 hours ago
Flights from Santa Lucía (NLU) to Santiago (SCL)
Origin airport
Felipe Ángeles Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Aerolineas Argentinas, Aeromexico, Air Canada, American Airlines, Copa, Delta, LATAM Airlines Group, United, avianca
Roundtrip price
$472
Distance
4115 mi

Mexico City to Santiago Flights

Whether you’re looking for a grand adventure or just want to get away for a last-minute break, flights from Mexico City to Santiago offer the perfect respite. Not only does exploring Santiago provide the chance to make some magical memories, dip into delectable dishes, and tour the local landmarks, but the cheap airfare means you won’t bust your budget. So no matter whether your ideal itinerary involves flying one way, non-stop, or round trip, you’re bound to find flights that match your schedule on Expedia, and at prices that won’t shock your wallet.

Bagging a cheap flight from Mexico City to Santiago may mean more dollars to spend on for one-of-a-kind souvenirs when you arrive, but it doesn’t mean you have to skimp on your travel experience, as Expedia offers a sizzling selection of cheap airlines that’ll put you in your happy place on their planes, whether that’s getting lost in a hair-raising airport thriller, dreaming on the passing landscape over a glass of bubbly, or jotting down your vacation bucket list at 38,000 feet. There’s also bound to be plenty of opportunities to snap a few photos of the high life that will make your friends green with envy. After all, enjoying the journey is part of the fun.

With so many affordable flights and so many wonderful adventures awaiting you, there’s no reason to put off booking a fantastic flight from MEX to SCL today. So don’t leave it to the last minute to make your dream trip a reality: pack your bags with your go-to travel accessories, put together your list of must-see attractions and can’t-miss activities, and get ready to broaden your horizons – with Expedia, the wonders of Santiago are only a plane trip away. Book your travel arrangements with us today!

If you would like to book flights to Santiago more flexibly many prefer to purchase one-way tickets with options to take different airlines. A one way ticket to Santiago is $257 now!

Frequently asked questions

How much is a one-way flight from MEX to Santiago International Airport?
Get ready to score a great deal, because Mexico City flights to Santiago start from $284. This info is based on the lowest fare found on Expedia for this journey with a departure date in the next three months. This airfare is for an Avianca flight, leaving Benito Juárez Intl. Airport on June 12 2024 and arriving at Santiago International Airport. This price was updated on June 4 2024 and has not changed since.
How long does it take to fly from Mexico City Intl. Airport (MEX) to Nuevo Pudahuel Airport?
LATAM Airlines operates a direct flight departing Mexico Airport at 7:00PM and coming in to land at Arturo Merino Benitez Airport (SCL) at 7:00AM — a travel time of 9 hours. Book your preferred seat, bring your headphones to keep you amused and the time will pass by quickly.
Is it cheaper to buy a plane ticket from Mexico Airport to Arturo Merino Benitez Airport (SCL) last minute?
When it comes to booking your flights, it’s always better to be prepared. While it’s possible to find a deal on a Mexico Airport to Nuevo Pudahuel Airport flight at the last minute, tickets usually don’t get cheaper as the date of departure nears. Based on flight pricing and demand studies in 2022, we have found that the sweet spot to book a domestic flight is between 28 – 35 days ahead. For international trips it’s between three and four months.
What is the cheapest airline flying from Mexico City Intl. Airport (MEX) to Arturo Merino Benitez Airport (SCL) in the next 90 days?
With fares starting at $284 for a flight from Mexico City to Santiago, Avianca is the cheapest airline found on Expedia. This price is based on airfares found on Expedia departing within the next 90 days and was updated on June 4 2024 and has not changed since. The flight leaves Mexico Airport on June 12 2024 and lands at SCL.
What's the cheapest price for a flight from MEX to Arturo Merino Benitez Airport (SCL) next month?
Lock in a flight from Mexico City to Santiago for only $248. This is the best price for this journey with a departure date in the next month. It’s an Avianca flight taking off from Mexico Airport on June 19 2024 and landing at Nuevo Pudahuel Airport. The airfare was updated on May 23 2024 and has not changed since. It was found after searching all available flights on Expedia within the next 30 days.
What airline has the least delays from Mexico Airport to Santiago International Airport?
If you’d prefer not to be waiting for hours — or worse, your vacation plans shelved due to a flight delay — opt for LATAM Airlines. Around 95% of its Mexico Airport to Santiago International Airport services get in on time. You can look up your flight status before leaving for the airport through the free Expedia App. It’ll also give you real-time notifications about things like gate changes, luggage carousel numbers and how to reach your hotel. Everything you need to know is in your pocket with this handy travel companion.
Can I find cheap nonstop flights from Benito Juárez Intl. Airport to Santiago International Airport in the next three months?
Get ready to save some money because we’ve discovered a roundtrip nonstop flight with LATAM Airlines Group in the next 90 days for $625. The price was updated on May 23 2024 and is based on fares found on Expedia with a departure date in the next three months. This flight from Mexico City to Santiago leaves Benito Juárez Intl. Airport on June 6 2024 and arrives at Nuevo Pudahuel Airport. The flight’s return date is June 10 2024.It’s easy to locate nonstop cheap flights from Benito Juárez Intl. Airport to Nuevo Pudahuel Airport by using our filters. Start by searching for your trip, then click on “Nonstop” under “Filter by” on the left-hand side of the page. Your results will be displayed with the lowest airfare first. If you don’t need to leave on a certain day, use our “Flexible dates” feature. You’ll be able to compare prices for nearby dates and walk away with the best deal possible.
What airports do you fly into for Santiago from Mexico City?
Arturo Merino Benitez Airport (SCL), San Felipe (SSD) and Valparaiso (VAP-Rodelillo Airfield) are your choices when connecting from Mexico City to Santiago. About 10 mi west of the heart of Santiago, Arturo Merino Benitez Airport (SCL) is the city’s major hub. Take into account things like flight departure and arrival times and the distance to your hotel before deciding on an airport. Palacio de la Moneda and San Cristobal Hill are two great attractions to put on your itinerary when you get to your destination.
What are the most popular departure times for flights from Benito Juárez Intl. Airport to Nuevo Pudahuel Airport?
For LATAM Airlines flights jetting from Mexico City Intl. Airport (MEX) to Santiago International Airport, the busiest period is between 7:00 PM - 8:00 PM. If you’d like to avoid any delays, head off in the morning. This way you’re likely to miss the air traffic that builds up in the skyways as the day goes by.
Can I change the date of my flight from Mexico Airport to Santiago International Airport?
It’s a breeze to make changes to your Mexico Airport to Arturo Merino Benitez Airport (SCL) journey yourself. Simply log in to the Expedia Trips portal and choose “change flight.” Look for new flights and book the one that works best. You’ll see an estimate of any flight change costs. Alternatively, use our Customer Service portal to connect with our Virtual Agent and get answers to all your questions.
Mexico City nearby Airports

Puebla

Santa Lucía

*Available to One Key members.