Title: The Best 2 Star Hotels in Cairo, IL from $69 | Expedia.com [Cairo Travel Guide](https://expedia.com/Cairo.dx6626)[Hotels in Cairo](https://expedia.com/Cairo-Hotels.d6626.Travel-Guide-Hotels)[Vacation Rentals in Cairo](https://expedia.com/Cairo-Vacation-Rentals.d6626.Travel-Guide-VacationRentals)[Flights to Cairo](https://expedia.com/Cheap-Flights-To-Cairo.d6626.Travel-Guide-Flights)[Car Rentals in Cairo](https://expedia.com/Car-Rentals-In-Cairo.d6626.Car-Rental-Guide)[Cairo Vacation Packages](https://expedia.com/Cairo.d6626.Destination-Travel-Guides) ![Cairo Ohio River Bridge traversing over the Ohio River at sunset](https://images.trvl-media.com/place/6626/5a2a2e7f-cbef-414c-a9c1-20af7a0fca3a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6626/5a2a2e7f-cbef-414c-a9c1-20af7a0fca3a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Cairo 2 Star Hotels Tonight [Mar 7 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=6626&startDate=2026-03-07&endDate=2026-03-08&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 8 - Mar 9](https://www.expedia.com/Hotel-Search?regionId=6626&startDate=2026-03-08&endDate=2026-03-09&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=6626&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=6626&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Cairo 2-star hotels ![Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/a5038447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/bbf96e9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/1ca277a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Charleston/Sikeston East MO [](https://www.expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) Charleston 6.8/10 (625 reviews) "Affordable for a quick one night stay. Restaurant and gas station next to hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Annette $62 nightly $69 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/f1c41457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/9d3e181d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking | Iron/ironing board, free cribs/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/96f1c1e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/74187a0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cairo I-57 [](https://www.expedia.com/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) Cairo 6.6/10 (282 reviews) "The quality was not what I expected for a "Quality Inn". It felt more light a Motel 6\. I was not satisfied at all." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ReShena $68 nightly $76 total Mar 13 - Mar 14 Total with taxes and fees [](https://www.expedia.com/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/a42cb957.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/08c2ace2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/15abbdc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/7fdae22d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverstone Hotel Charleston-Sikeston [](https://www.expedia.com/Charleston-Hotels-The-Riverstone-Hotel.h20594.Hotel-Information) Charleston 6.8/10 (408 reviews) "The staff was very friendly and accommodating " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Arturo $70 nightly $78 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Charleston-Hotels-The-Riverstone-Hotel.h20594.Hotel-Information) ![Basic Double Room | Living area](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/e95f9062.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/f3adf3f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/bbe54b21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Double Room | Free WiFi](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/1016c5b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Center Motel [](https://www.expedia.com/La-Center-Hotels-La-Center-Motel.h99665264.Hotel-Information) La Center 7.6/10 Good (18 reviews) "Quiet and convenient." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alma $65 nightly $70 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/La-Center-Hotels-La-Center-Motel.h99665264.Hotel-Information) ![Room, 1 King Bed, Non Smoking | View from room](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/183a17d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/ec6ce079.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/8720ff7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, alarm clocks](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/228b486a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eagle Inn Charleston [](https://www.expedia.com/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) Charleston 6.6/10 (105 reviews) "Convenient " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcelle $64 nightly $71 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F2Star-Cairo-Hotels.s20-0-d6626.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F2Star-Cairo-Hotels.s20-0-d6626.Travel-Guide-Filter-Hotels) ## Explore similar 3-star hotels Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Cairo. ![Upscale & Quiet Paducah Retreat on 15 Acres!](https://images.trvl-media.com/lodging/94000000/93570000/93561400/93561320/a54bc9d1_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Upscale & Quiet Paducah Retreat on 15 Acres! West Paducah KY [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F21%2F2026&endDate=3%2F22%2F2026&selected=93561320&PinnedHotelID=93561320&HadPinnedHotel=true®ionId=6626) 10/10 Exceptional! (1 review) [](https://expedia.com/West-Paducah-Hotels-Upscale-Quiet-Paducah-Retreat-On-15-Acres.h93561320.Hotel-Information) ![Quiet Country Stay: Modern Home Near Paducah](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/9b8cfc2e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quiet Country Stay: Modern Home Near Paducah Cunningham KY $271 nightly $290 total Mar 9 - Mar 10 Total with taxes and fees [](https://expedia.com/Quiet-Country-Stay-Modern-Home-Near-Paducah.h122892138.Hotel-Information) Still don't see what you're looking for? [See all properties in Cairo.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F8%2F2026&endDate=3%2F9%2F2026®ionId=6626&star=20) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F8%2F2026&endDate=3%2F9%2F2026®ionId=6626&star=20&star=20&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F8%2F2026&endDate=3%2F9%2F2026®ionId=6626&star=20&star=20&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F8%2F2026&endDate=3%2F9%2F2026®ionId=6626&star=20&star=20&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F8%2F2026&endDate=3%2F9%2F2026®ionId=6626&star=20&star=20&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F8%2F2026&endDate=3%2F9%2F2026®ionId=6626&star=20&star=20&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Cairo At the confluence of the Mississippi and Ohio rivers, explore Cairo's historic Fort Defiance Park with its sweeping water views. History buffs shouldn't miss the Custom House Museum, where you can discover artifacts from this once-thriving river port town. [See all hotels in Cairo](https://www.expedia.com/Hotel-Search?startDate=2026-03-21&endDate=2026-03-22&adults=2®ionId=6626) ![Cairo Ohio River Bridge traversing over the Ohio River at sunset](https://images.trvl-media.com/place/6626/5a2a2e7f-cbef-414c-a9c1-20af7a0fca3a.jpg?impolicy=fcrop&w=899&h=599&p=1&q=high) ## Top Cairo Hotel Reviews ![Super 8 by Wyndham Charleston/Sikeston East MO](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6_y.jpg) ### Super 8 by Wyndham Charleston/Sikeston East MO 6/10 Okay "The room needed updated" [](https://expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Eagle Inn Charleston](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/183a17d9_y.jpg) ### Eagle Inn Charleston 2/10 Terrible "The hotel needs a renovation. For the price I didn’t expect much, but it feels neglected." [](https://expedia.com/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) ## Find out more about Cairo When you've got to get away to a new or favorite destination without breaking the bank, Cairo awaits with top 2 Star hotels and a change of scenery. Find a new fave bakery or plaza nearby and enjoy some R & R, or stay on your feet visiting the top attractions that draw of visitors. You're about to find out why both locals and travelers love this place. Pack your bags and get ready for fun and a relaxing stay in a city with excellent overall 2 Star Hotel ratings of 4.0\. In fact, more than half of past guest reviews recommend their 2 Star Hotel in Cairo, and it's time to find out why. ### The Right Place at the Perfect Price 2 Star hotels are in high demand in Cairo. You'll find the best deals right here, so book early and save on a great getaway. Thanks to several convenient locations and comfortable amenities, past globetrotters have found a place to stay that's just right. Be one of the first travelers to leave a review and share your experience. The best travel is all about hospitality, and these 2 Star hotels have a strong service rating of 4.7\. Plus, with an average cleanliness rating of 4.3, these rooms are sparkling and restful. When you book with Expedia, you can stay all over the world, and the journey starts in Cairo. ### Book Your 2-Star Accommodation! Almost all visitors recommend traveling to Cairo. Recently, traveling to this region has become cheaper due to more supply. 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Marie (CIU) to Cairo (CIR) ](https://www.expedia.com/lp/flights/ciu/cir/sault-ste-marie-to-cairo) - [Flights from Louisville (SDF) to Cairo (CIR) ](https://www.expedia.com/lp/flights/sdf/cir/louisville-to-cairo) - [Flights from Green Bay (GRB) to Cairo (CIR) ](https://www.expedia.com/lp/flights/grb/cir/green-bay-to-cairo) - [Flights from Philadelphia (PHL) to Cairo (CIR) ](https://www.expedia.com/lp/flights/phl/cir/philadelphia-to-cairo) - [Flights from New York (JFK) to Cairo (CIR) ](https://www.expedia.com/lp/flights/jfk/cir/new-york-to-cairo) - [Flights from Kilimanjaro (JRO) to Cairo (CIR) ](https://www.expedia.com/lp/flights/jro/cir/kilimanjaro-to-cairo) - [Flights from Nagoya (NGO) to Cairo (CIR) ](https://www.expedia.com/lp/flights/ngo/cir/nagoya-to-cairo) - [Flights from Barcelona (BCN) to Cairo (CIR) ](https://www.expedia.com/lp/flights/bcn/cir/barcelona-to-cairo) - [Flights from Newburgh (SWF) to Cairo (CIR) ](https://www.expedia.com/lp/flights/swf/cir/newburgh-to-cairo) - [Flights from Ocala (OCF) to Cairo (CIR) ](https://www.expedia.com/lp/flights/ocf/cir/ocala-to-cairo) - [Flights from London (LHR) to Cairo (CIR) ](https://www.expedia.com/lp/flights/lhr/cir/london-to-cairo) - [Flights from Tokyo (NRT) to Cairo (CIR) ](https://www.expedia.com/lp/flights/nrt/cir/tokyo-to-cairo) - [Flights from Bishkek (FRU) to Cairo (CIR) ](https://www.expedia.com/lp/flights/fru/cir/bishkek-to-cairo) - [Flights from Kunming (KMG) to Cairo (CIR) ](https://www.expedia.com/lp/flights/kmg/cir/kunming-to-cairo) - [Flights from Leesburg (LEE) to Cairo (CIR) ](https://www.expedia.com/lp/flights/lee/cir/leesburg-to-cairo) - [Flights from South Bend (SBN) to Cairo (CIR) ](https://www.expedia.com/lp/flights/sbn/cir/south-bend-to-cairo) - [Flights from San Francisco (SFO) to Cairo (CIR) ](https://www.expedia.com/lp/flights/sfo/cir/san-francisco-to-cairo) - [Flights from Grand Rapids (GRR) to Cairo (CIR) ](https://www.expedia.com/lp/flights/grr/cir/grand-rapids-to-cairo) - [Flights from Mexico City (MEX) to Cairo (CIR) ](https://www.expedia.com/lp/flights/mex/cir/mexico-city-to-cairo) - 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