A steel bridge with a sunset in the background.

Find 2 Star Hotels in Cairo, IL from $66

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Check availability on Cairo 2 Star Hotels

Tonight
Oct 5 - Oct 6
Tomorrow
Oct 6 - Oct 7
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Cairo 2-star hotels

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.
A restaurant with wooden cabinets, a refrigerator, and a counter with various items. There are tables and chairs for dining.
A reception area with a sofa, a coffee table, a potted plant, and a framed picture on the wall.
A hotel with a covered entrance, a sign for the brand, and a parking lot with cars.

1. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
Charleston
United States
William
$60 nightly
$66 total
Oct 6 - Oct 7
Total with taxes and fees
Super 8 by Wyndham Charleston/Sikeston East MO
A building with a fountain and flower beds in front.
A hotel room with a beige sofa, two patterned armchairs, a ceiling fan, a flat-screen TV, and a window with curtains.
A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.
A modern kitchen with dark wooden cabinets, a central island, and a ceiling fan.

2. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
Charleston
United States
Kathleen
$66 nightly
$74 total
Oct 7 - Oct 8
Total with taxes and fees
The Riverstone Hotel Charleston-Sikeston
A hotel lobby with a reception desk, seating area, and a large window.
A hotel room with a desk, chair, television, and a lamp.
A hotel lobby with a reception desk, two armchairs, a coffee table, and large windows with potted plants.
A Quality Inn hotel with a green sign, a covered outdoor area, and a parking lot.

3. Quality Inn Cairo I-57

Quality Inn Cairo I-57
Cairo
United States
Santiago
$68 nightly
$76 total
Oct 16 - Oct 17
Total with taxes and fees
Quality Inn Cairo I-57
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a painting on the wall.
A bathroom with yellow walls, a wooden cabinet, a sink, a mirror, and a hanging towel rack.
A motel with a red roof and beige walls, a parking lot, and a signboard.
A reception desk with a computer, a framed picture on the wall, and a vase with flowers.

4. La Center Motel

La Center Motel
La Center
United States
Carrie
$65 nightly
$70 total
Oct 6 - Oct 7
Total with taxes and fees
La Center Motel
A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.
A kitchen with wooden cabinets, a granite countertop, a built-in microwave, and a window with a view.
A hotel room with two beds, a nightstand, a lamp, and a window with curtains.
A bathroom with a sink, mirror, towel rack, shower, and toilet.

5. Eagle Inn Charleston

Eagle Inn Charleston
Charleston
United States
Jackson
$66 nightly
$73 total
Oct 6 - Oct 7
Total with taxes and fees
Eagle Inn Charleston
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Explore similar 3-star hotels

Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Cairo.
Upscale & Quiet Paducah Retreat on 15 Acres!

Upscale & Quiet Paducah Retreat on 15 Acres!

West Paducah KY
Get rates
10/10 Exceptional! (1 review)
Upscale & Quiet Paducah Retreat on 15 Acres!
Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah

Cunningham KY
$271 nightly
$290 total
Oct 6 - Oct 7
Total with taxes and fees
Quiet Country Stay: Modern Home Near Paducah
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Cairo

At the confluence of the Mississippi and Ohio rivers, explore Cairo's historic Fort Defiance Park with its sweeping water views. History buffs shouldn't miss the Custom House Museum, where you can discover artifacts from this once-thriving river port town.

See all hotels in Cairo
A steel bridge with a sunset in the background.

Top Cairo Hotel Reviews

La Center Motel

La Center Motel

10/10 Excellent
"Great AC unit in the room!"
Jonathan 1-night trip
Posted 2 months ago
La Center Motel
Eagle Inn Charleston

Eagle Inn Charleston

10/10 Excellent
"Great"
Jackson 1-night trip
Posted 6 months ago
Eagle Inn Charleston

Find out more about Cairo

When you've got to get away to a new or favorite destination without breaking the bank, Cairo awaits with top 2 Star hotels and a change of scenery. Find a new fave bakery or plaza nearby and enjoy some R & R, or stay on your feet visiting the top attractions that draw of visitors. You're about to find out why both locals and travelers love this place. Pack your bags and get ready for fun and a relaxing stay in a city with excellent overall 2 Star Hotel ratings of 4.0. In fact, more than half of past guest reviews recommend their 2 Star Hotel in Cairo, and it's time to find out why.

The Right Place at the Perfect Price

2 Star hotels are in high demand in Cairo. You'll find the best deals right here, so book early and save on a great getaway. Thanks to several convenient locations and comfortable amenities, past globetrotters have found a place to stay that's just right. Be one of the first travelers to leave a review and share your experience. The best travel is all about hospitality, and these 2 Star hotels have a strong service rating of 4.7. Plus, with an average cleanliness rating of 4.3, these rooms are sparkling and restful. When you book with Expedia, you can stay all over the world, and the journey starts in Cairo.

Book Your 2-Star Accommodation!

Almost all visitors recommend traveling to Cairo. Recently, traveling to this region has become cheaper due to more supply. Take advantage of the 2 Star Hotel availability and easy-going atmosphere.

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