A coastal fortress with a stone wall and a tiled-roof building.

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Check availability on Syracuse 4 Star Hotels

Tonight
Aug 9 - Aug 10
Tomorrow
Aug 10 - Aug 11
Next weekend
Aug 14 - Aug 16
In two weeks
Aug 21 - Aug 23

Our top choices for Syracuse 4-star hotels

1. Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
Ortigia
United States
Sylvia
$205 nightly
$237 total
Aug 19 - Aug 20
Total with taxes and fees
Algila' Ortigia Charme Hotel

2. Dolce by Wyndham Siracusa I Monasteri Golf & Spa

Dolce by Wyndham Siracusa I Monasteri Golf & Spa
Syracuse
United Kingdom
Joshua
$94 nightly
$107 total
Aug 9 - Aug 10
Total with taxes and fees
Dolce by Wyndham Siracusa I Monasteri Golf & Spa

3. UNA Hotels One Siracusa Wellness & SPA

UNA Hotels One Siracusa Wellness & SPA
Grottasanta
United States
Tanasha
$163 nightly
$186 total
Sep 6 - Sep 7
Total with taxes and fees
UNA Hotels One Siracusa Wellness & SPA

4. Hotel Parco delle Fontane

Hotel Parco delle Fontane
Tiche
United States
ROBERT
$139 nightly
$159 total
Aug 19 - Aug 20
Total with taxes and fees
Hotel Parco delle Fontane

5. Grand Hotel Villa Politi

Grand Hotel Villa Politi
Grottasanta
United States
Paula
$166 nightly
$189 total
Sep 6 - Sep 7
Total with taxes and fees
Grand Hotel Villa Politi

6. Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection
Ortigia
United States
Naila
$295 nightly
$336 total
Aug 31 - Sep 1
Total with taxes and fees
Palazzo Artemide - VRetreats, SLH Collection

7. Grande Albergo Alfeo

Grande Albergo Alfeo
Santa Lucia
Australia
Janet
$125 nightly
$143 total
Aug 31 - Sep 1
Total with taxes and fees
Grande Albergo Alfeo

8. Mercure Siracusa Prometeo

Mercure Siracusa Prometeo
Neapolis
United States
John
$169 nightly
$204 total
Aug 23 - Aug 24
Total with taxes and fees
Mercure Siracusa Prometeo

9. Residence Archimede

Residence Archimede
Syracuse
United States
Anthony
$150 nightly
$171 total
Sep 7 - Sep 8
Total with taxes and fees
Residence Archimede

10. Eureka Palace Hotel Spa

Eureka Palace Hotel Spa
Syracuse
Ireland
Sharon
$103 nightly
$117 total
Aug 31 - Sep 1
Total with taxes and fees
Eureka Palace Hotel Spa

11. Albatros Hotel

Albatros Hotel
Syracuse
United Kingdom
lynda
$109 nightly
$126 total
Aug 16 - Aug 17
Total with taxes and fees
Albatros Hotel

12. Charme Hotel Henry's House

Charme Hotel Henry's House
Ortigia
United States
Matthew
$218 nightly
$251 total
Aug 9 - Aug 10
Total with taxes and fees
Charme Hotel Henry's House

13. VOI Arenella Resort

VOI Arenella Resort
Syracuse
United States
Frank
VOI Arenella Resort

14. Hotel Relax

Hotel Relax
Epipoli
Italy
marselli
$135 nightly
$154 total
Sep 6 - Sep 7
Total with taxes and fees
Hotel Relax

15. Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
Santa Lucia
Australia
Alan
$152 nightly
$173 total
Aug 24 - Aug 25
Total with taxes and fees
Hotel Palazzo Cavalieri

16. Hotel Villamare

Hotel Villamare
Syracuse
United Kingdom
Ceri
$222 nightly
$253 total
Sep 8 - Sep 9
Total with taxes and fees
Hotel Villamare

17. Addauro Resort

Addauro Resort
Syracuse
United Kingdom
Carlo
$107 nightly
$122 total
Sep 8 - Sep 9
Total with taxes and fees
Addauro Resort

18. Hotel Panorama

Hotel Panorama
Neapolis
United States
rosario
$97 nightly
$110 total
Aug 9 - Aug 10
Total with taxes and fees
Hotel Panorama

19. Villa Fanusa

Villa Fanusa
Syracuse
United Kingdom
J
$104 nightly
$119 total
Sep 8 - Sep 9
Total with taxes and fees
Villa Fanusa

20. Aretusa Palace Hotel

Aretusa Palace Hotel
Syracuse
Italy
Vincenzo
Aretusa Palace Hotel
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Syracuse.
Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection

Via Riva Nazario Sauro Syracuse SR
$401 nightly
$453 total
Aug 13 - Aug 14
Total with taxes and fees
Ortea Palace Hotel, Sicily, Autograph Collection
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

Viale Mazzini, 12 Syracuse SR
$323 nightly
$367 total
Aug 10 - Aug 11
Total with taxes and fees
Grand Hotel Ortigia Siracusa
Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Passeggio Adorno 10/12 Syracuse SR
$630 nightly
$704 total
Aug 16 - Aug 17
Total with taxes and fees
Grand Hotel Des Ètrangers - The Leading Hotels of the World
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Syracuse

Ancient Greek ruins in the Archaeological Park include the impressive Teatro Greco where summer performances still take place. Wander through Ortygia's narrow streets to discover the Duomo, built around a former Greek temple with columns still visible from inside.

See all hotels in Syracuse
An ancient amphitheater with stone ruins and a grassy field.

Top Syracuse Hotel Reviews

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

10/10 Excellent
"Fantastic property, fab breakfast and lovely staff, what more could you want!"
Rachael 1-night trip
Posted 3 hours ago
Algila' Ortigia Charme Hotel
 Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection

10/10 Excellent
"Absolutely magnificent stay!!!! Surprised no turn down service but otherwise zero complaints!!!"
Annie 4-night trip
Posted 4 days ago
Palazzo Artemide - VRetreats, SLH Collection
UNA Hotels One Siracusa Wellness & SPA

UNA Hotels One Siracusa Wellness & SPA

10/10 Excellent
"It’s a really beautiful hotel. Great staff, great food, AC works, beautiful spa. It’s in central place but not in the midst of all the chaos at the same time!"
Tanasha 2-night trip
Posted 1 month ago
UNA Hotels One Siracusa Wellness & SPA
Hotel Parco delle Fontane

Hotel Parco delle Fontane

10/10 Excellent
"Very nice hotel outside of busy area but easy to access downtown Ortigia and Siracusa Unfortunately was only there for one night but pool looked wonderful and historic ambiance in hotel was interesting to see. Parking was free and breakfast was wonderful with so many options! Will definitely revisit when I’m the area again!"
Giovanna 1-night trip
Posted 1 month ago
Hotel Parco delle Fontane
Grand Hotel Villa Politi

Grand Hotel Villa Politi

10/10 Excellent
"The rooms are really nice, smaller than pictures, but nice. View was ok, small porthole in a Concrete wall. Pool was great, breakfast was amazing. Staff are very friendly and attentive. We had a car so it was 7 minute drive to parking outside Ortigia every evening plus we did day trips to Noto, Catania, Marzemeni, Brucoli. Parking was easy and convenient. Great value for the price. I would stay again. We rented a self captained boat as well, coast is beautiful, and we ate every night in Ortigia. We split our time between Syracusa-Ortigia and Taormina."
Brian 5-night trip
Posted 2 months ago
Grand Hotel Villa Politi
Eureka Palace Hotel Spa

Eureka Palace Hotel Spa

8/10 Good
"The room was spacious, very clean, balcony was huge with a view over the front of the hotel. The staff were very friendly. Particularly the resteraunt staff. Veronica was very helpful with the menu and very courteous. The food was excellent both for breakfast & Dinner. A minor observation was that the power sockets in the room required a different adapter, not supplied , we had to loan from reception. Also there was no tea making facilities in the room , we had to ask for this from reception, and inconvenience rather than a complaint, we should of been told of this on checking in. The Bars both inside & by the pool were not operational., throughout our stay. Overall it was a very nice hotel oh and the pools were very good & well maintained. Anyone who may be planning to go there should be aware that it's a remote location, no local transport whatsoever. Imperative that you need a car. There is no shuttle bus available. A taxi cost £60 to the town. I don't think I've been over critical, but I hope this review helps you as a potential visitor."
Noel 6-night trip
Posted 2 months ago
Eureka Palace Hotel Spa
Dolce by Wyndham Siracusa I Monasteri Golf & Spa

Dolce by Wyndham Siracusa I Monasteri Golf & Spa

10/10 Excellent
"Great upgrade Wonderful place "
Veronique 1-night trip
Posted 10 months ago
Dolce by Wyndham Siracusa I Monasteri Golf & Spa

Find out more about Syracuse

The outset of any holiday gets started with picking a location. Syracuse is a popular option with tourists because of everything it offers. Location is everything, but that accounts for more than the area you are flying into. Now that you have got a feeling for this city, it's time you to get to know your residence for the next several days.

Properties as Scenic as the City

Syracuse saw its fair share of visitors in the last year. Expedia's review section features tips and tricks on which accommodation will satisfy your desires for a wonderful vacation. The resorts found here aim to make your stay as gratifying as your days and nights hanging out in Syracuse. These hotels aim to make the grounds and facilities welcoming during your stay. You won't have to search long for to keep up with your exercise schedule, an invigorating spa treatment, or nice dinner.

Rooms have been designed to keep you as comfortable as possible, with amenities like ultra-comfortable bedding, designer bathroom products, and in-room coffee or tea. So, lay back and relax. Moreover, if you find that you're need of anything further, you can rest assured the staff will do their best to ensure you remain satisfied during your time. These properties are so lovely that you'll regret the day you have to check-out.

Book a 4-Star Hotel in Syracuse Today!

A holiday to Syracuse should be one where you won't have to concern yourself about the little things. With Expedia, you can get great deals on world-class accommodations to take your trip to the next level.

Frequently asked questions

What are the best 4-star hotels in Syracuse?
Look forward to 4-star hotel comfort at Algila Ortigia Charme Hotel. Rated highly by many of our guests, it comes with concierge services and room service. Also take a look at Hotel Roma. Premium bedding and concierge services help make this retreat another popular pick in Syracuse.
How much does it cost to stay in a 4-star hotel in Syracuse?
With Expedia's sort and search filters, locking in a superb deal on a 4-star hotel in Syracuse just got simpler. Start by keying in your chosen travel dates and length of your trip. Then sort the results by price and pick the option that best suits your budget and style.
  • Search for the lowest price from $367
What's the difference between 5-star and 4-star hotels in Syracuse?
Offering an inviting traveler experience and upscale décor, 4-star hotels are a fabulous option for your Syracuse vacation. These kinds of accommodations generally come with lots of handy amenities that make it simple to kick back and relax — think complimentary bathrobes, gyms and pools. Or live in the lap of luxury at a 5-star hotel designed to spoil you with high-end perks and amenities. A personalized service, oversized bathrooms and world-class dining are typically featured at these plush retreats.

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