A coastal fortress with a stone wall and a tiled-roof building.

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Check availability on Syracuse 4 Star Hotels

Tonight
Aug 25 - Aug 26
Tomorrow
Aug 26 - Aug 27
This weekend
Aug 28 - Aug 30
Next weekend
Sep 4 - Sep 6

Our top choices for Syracuse 4-star hotels

1. Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
Ortigia
United States
Daniel
$234 nightly
$269 total
Aug 31 - Sep 1
Total with taxes and fees
Algila' Ortigia Charme Hotel

2. Dolce by Wyndham Siracusa I Monasteri Golf & Spa

Dolce by Wyndham Siracusa I Monasteri Golf & Spa
Syracuse
United Kingdom
Joshua
$94 nightly
$107 total
Sep 20 - Sep 21
Total with taxes and fees
Dolce by Wyndham Siracusa I Monasteri Golf & Spa

3. UNA Hotels One Siracusa Wellness & SPA

UNA Hotels One Siracusa Wellness & SPA
Grottasanta
United States
Tanasha
$132 nightly
$150 total
Aug 31 - Sep 1
Total with taxes and fees
UNA Hotels One Siracusa Wellness & SPA

4. Hotel Parco delle Fontane

Hotel Parco delle Fontane
Tiche
United States
ROBERT
$134 nightly
$153 total
Aug 30 - Aug 31
Total with taxes and fees
Hotel Parco delle Fontane

5. Grand Hotel Villa Politi

Grand Hotel Villa Politi
Grottasanta
France
abdulrahman
$149 nightly
$170 total
Aug 31 - Sep 1
Total with taxes and fees
Grand Hotel Villa Politi

6. Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection
Ortigia
United States
Victor
$250 nightly
$287 total
Aug 31 - Sep 1
Total with taxes and fees
Palazzo Artemide - VRetreats, SLH Collection

7. Grande Albergo Alfeo

Grande Albergo Alfeo
Santa Lucia
Australia
Janet
$100 nightly
$114 total
Sep 12 - Sep 13
Total with taxes and fees
Grande Albergo Alfeo

8. Mercure Siracusa Prometeo

Mercure Siracusa Prometeo
Neapolis
United States
John
$170 nightly
$206 total
Sep 13 - Sep 14
Total with taxes and fees
Mercure Siracusa Prometeo

9. Residence Archimede

Residence Archimede
Syracuse
United States
Anthony
$140 nightly
$154 total
Sep 8 - Sep 9
Total with taxes and fees
Residence Archimede

10. Eureka Palace Hotel Spa

Eureka Palace Hotel Spa
Syracuse
Ireland
Sharon
$103 nightly
$117 total
Sep 20 - Sep 21
Total with taxes and fees
Eureka Palace Hotel Spa

11. Albatros Hotel

Albatros Hotel
Syracuse
United Kingdom
lynda
$108 nightly
$123 total
Aug 31 - Sep 1
Total with taxes and fees
Albatros Hotel

12. Charme Hotel Henry's House

Charme Hotel Henry's House
Ortigia
United States
Frances
$300 nightly
$341 total
Aug 29 - Aug 30
Total with taxes and fees
Charme Hotel Henry's House

13. VOI Arenella Resort

VOI Arenella Resort
Syracuse
United States
Frank
VOI Arenella Resort

14. Hotel Relax

Hotel Relax
Epipoli
Italy
marselli
$131 nightly
$149 total
Sep 23 - Sep 24
Total with taxes and fees
Hotel Relax

15. Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
Santa Lucia
Australia
Alan
$102 nightly
$116 total
Sep 8 - Sep 9
Total with taxes and fees
Hotel Palazzo Cavalieri

16. Hotel Villamare

Hotel Villamare
Syracuse
United Kingdom
Ceri
$202 nightly
$231 total
Sep 25 - Sep 26
Total with taxes and fees
Hotel Villamare

17. Addauro Resort

Addauro Resort
Syracuse
United Kingdom
avi
$109 nightly
$124 total
Sep 24 - Sep 25
Total with taxes and fees
Addauro Resort

18. Hotel Panorama

Hotel Panorama
Neapolis
United States
rosario
$105 nightly
$119 total
Sep 3 - Sep 4
Total with taxes and fees
Hotel Panorama

19. Villa Fanusa

Villa Fanusa
Syracuse
United Kingdom
J
$100 nightly
$114 total
Sep 19 - Sep 20
Total with taxes and fees
Villa Fanusa

20. Aretusa Palace Hotel

Aretusa Palace Hotel
Syracuse
Italy
Vincenzo
Aretusa Palace Hotel
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Syracuse.
Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection

Via Riva Nazario Sauro Syracuse SR
$406 nightly
$459 total
Aug 26 - Aug 27
Total with taxes and fees
9.2/10 Wonderful! (273 reviews)
Ortea Palace Hotel, Sicily, Autograph Collection
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

Viale Mazzini, 12 Syracuse SR
$319 nightly
$363 total
Aug 27 - Aug 28
Total with taxes and fees
9/10 Wonderful! (620 reviews)
Grand Hotel Ortigia Siracusa
Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Passeggio Adorno 10/12 Syracuse SR
$606 nightly
$679 total
Aug 29 - Aug 30
Total with taxes and fees
Grand Hotel Des Ètrangers - The Leading Hotels of the World
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Syracuse

Ancient Greek ruins in the Archaeological Park include the impressive Teatro Greco where summer performances still take place. Wander through Ortygia's narrow streets to discover the Duomo, built around a former Greek temple with columns still visible from inside.

See all hotels in Syracuse
An ancient amphitheater with stone ruins and a grassy field.

Top Syracuse Hotel Reviews

Hotel Parco delle Fontane

Hotel Parco delle Fontane

10/10 Excellent
"Please clarify the specific procedures or instructions for gaining access to the facility, particularly regarding the address displayed at the gate."
Salvatore 1-night trip
Posted 1 hour ago
Hotel Parco delle Fontane
Grande Albergo Alfeo

Grande Albergo Alfeo

10/10 Excellent
"Great spot in Siracusa and easy walk into Ortigia. The staff was friendly and Alessandro was a great help to us and answered our questions in English and Italian. Plus who can resist the refreshingly delicious free granita."
Elizabeth 3-night trip
Posted 14 hours ago
Grande Albergo Alfeo
Grand Hotel Villa Politi

Grand Hotel Villa Politi

10/10 Excellent
"A wonderful luxury hotel albeit our rooms were a bit small compared to the others. (2 single occupancy rooms). Very clean well serviced. Like a trip back in time to the golden age of luxury. Would definitely return and highly recommend this hotel. Extremely excellent value for money."
Elaine 3-night trip
Posted 1 day ago
Grand Hotel Villa Politi
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

10/10 Excellent
"Everything was great Staff was amazing very helpful Breakfast was very good"
Helena 2-night trip
Posted 2 days ago
Algila' Ortigia Charme Hotel
 Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection

10/10 Excellent
"Incredible place and location. Favorite time and place in Sicily."
Victor 2-night trip
Posted 4 days ago
Palazzo Artemide - VRetreats, SLH Collection
VOI Arenella Resort

VOI Arenella Resort

10/10 Excellent
"Really lovely, well maintained resort, with attractive grounds. There are 2 large pools which are very clean and offer shallow children's section alongside a deeper section. One of the pools is quieter and the other has loud music, we enjoyed using both of them. The staff are very helpful, friendly and welcoming. Being mainly English speakers, we didn't find it difficult to communicate with the staff at all. We went to the beach a couple of times, it is 600m away but the hotel has transport to take people which runs most of the day. We went to the evening shows most night but they are mostly in Italian so we struggled a bit, however, our 4 year old daughter still enjoyed dancing along and watching parts of it. The best part is the food! We had delicious pastas, pizza, fish, vegetables, fruit... the food is varied and fresh. Also delicious deserts. The food quality is really good. The drinks need to be improved - they are served mostly in small plastic cups which isn't ideal. To note - we were all inclusive and paid more for a Superior room which was definitely worth it as you get access to a more premium restaurant and you get reserved beach chairs, beach towels, etc. Overall it beat my expectations and we'd go again."
Selina 7-night trip
Posted 2 weeks ago
VOI Arenella Resort
UNA Hotels One Siracusa Wellness & SPA

UNA Hotels One Siracusa Wellness & SPA

10/10 Excellent
"It’s a really beautiful hotel. Great staff, great food, AC works, beautiful spa. It’s in central place but not in the midst of all the chaos at the same time!"
Tanasha 2-night trip
Posted 2 months ago
UNA Hotels One Siracusa Wellness & SPA
Dolce by Wyndham Siracusa I Monasteri Golf & Spa

Dolce by Wyndham Siracusa I Monasteri Golf & Spa

10/10 Excellent
"Great upgrade Wonderful place "
Veronique 1-night trip
Posted 10 months ago
Dolce by Wyndham Siracusa I Monasteri Golf & Spa

Find out more about Syracuse

The outset of any holiday gets started with picking a location. Syracuse is a popular option with tourists because of everything it offers. Location is everything, but that accounts for more than the area you are flying into. Now that you have got a feeling for this city, it's time you to get to know your residence for the next several days.

Properties as Scenic as the City

Syracuse saw its fair share of visitors in the last year. Expedia's review section features tips and tricks on which accommodation will satisfy your desires for a wonderful vacation. The resorts found here aim to make your stay as gratifying as your days and nights hanging out in Syracuse. These hotels aim to make the grounds and facilities welcoming during your stay. You won't have to search long for to keep up with your exercise schedule, an invigorating spa treatment, or nice dinner.

Rooms have been designed to keep you as comfortable as possible, with amenities like ultra-comfortable bedding, designer bathroom products, and in-room coffee or tea. So, lay back and relax. Moreover, if you find that you're need of anything further, you can rest assured the staff will do their best to ensure you remain satisfied during your time. These properties are so lovely that you'll regret the day you have to check-out.

Book a 4-Star Hotel in Syracuse Today!

A holiday to Syracuse should be one where you won't have to concern yourself about the little things. With Expedia, you can get great deals on world-class accommodations to take your trip to the next level.

Frequently asked questions

What are the best 4-star hotels in Syracuse?
Look forward to 4-star hotel comfort at Algila Ortigia Charme Hotel. Rated highly by many of our guests, it comes with concierge services and room service. Also take a look at Hotel Roma. Premium bedding and concierge services help make this retreat another popular pick in Syracuse.
How much does it cost to stay in a 4-star hotel in Syracuse?
With Expedia's sort and search filters, locking in a superb deal on a 4-star hotel in Syracuse just got simpler. Start by keying in your chosen travel dates and length of your trip. Then sort the results by price and pick the option that best suits your budget and style.
  • Search for the lowest price from $363
What's the difference between 5-star and 4-star hotels in Syracuse?
Offering an inviting traveler experience and upscale décor, 4-star hotels are a fabulous option for your Syracuse vacation. These kinds of accommodations generally come with lots of handy amenities that make it simple to kick back and relax — think complimentary bathrobes, gyms and pools. Or live in the lap of luxury at a 5-star hotel designed to spoil you with high-end perks and amenities. A personalized service, oversized bathrooms and world-class dining are typically featured at these plush retreats.

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