A coastal fortress with a stone wall and a tiled-roof building.

Find 4 Star Hotels in Syracuse from $103

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Syracuse 4 Star Hotels

Tonight
Aug 28 - Aug 29
Tomorrow
Aug 29 - Aug 30
This weekend
Aug 28 - Aug 30
Next weekend
Sep 4 - Sep 6

Our top choices for Syracuse 4-star hotels

A historic building with a central entrance, multiple balconies, and a large potted plant in front.
An interior corridor with an arched stone doorway, a staircase, and a table with a vase of flowers.
An interior view of a restaurant with stone arches, wooden beams, and tables set for dining.
A rooftop terrace with outdoor seating, a view of the sea, and parked cars.

1. Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
Ortigia
United Kingdom
Rachael
$234 nightly
$269 total
Aug 31 - Sep 1
Total with taxes and fees
Algila' Ortigia Charme Hotel
A large, multi-story building with a grand staircase leading to the entrance, stone walls, and multiple illuminated windows.
A swimming pool with water features, outdoor seating, and a bar area.
An outdoor seating area with tables and chairs, a large tree, and a building with a tiled roof.
A waterfront promenade with clear water, a stone walkway, and a row of beach umbrellas.

2. Dolce by Wyndham Siracusa I Monasteri Golf & Spa

Dolce by Wyndham Siracusa I Monasteri Golf & Spa
Syracuse
United Kingdom
Joshua
$93 nightly
$107 total
Sep 13 - Sep 14
Total with taxes and fees
Dolce by Wyndham Siracusa I Monasteri Golf & Spa
A bakery display with various baked goods and a sign indicating apple and jam cake.
A modern hotel with a glass facade, outdoor seating area, and a visible logo on the building.
An outdoor patio area with seating and potted plants, under a night sky.
A spa area with a reflective pool, a candlelit candelabra, and a cave-like wall.

3. UNA Hotels One Siracusa Wellness & SPA

UNA Hotels One Siracusa Wellness & SPA
Grottasanta
United States
Tanasha
$144 nightly
$164 total
Sep 28 - Sep 29
Total with taxes and fees
UNA Hotels One Siracusa Wellness & SPA
A poolside setting with a person relaxing, a table with a drink and fruit, and a view of the pool and chairs in the background.
A buffet with various food items, including pastries and a meat display, in a well-lit room with a neutral color scheme.
A multi-story hotel with a covered entrance, a well-maintained lawn, and a classic architectural style.
A courtyard with tables set up for an event, surrounded by buildings with large windows and a well-lit exterior.

4. Hotel Parco delle Fontane

Hotel Parco delle Fontane
Tiche
United States
Tony
$134 nightly
$152 total
Aug 30 - Aug 31
Total with taxes and fees
Hotel Parco delle Fontane
A coastal terrace with wicker furniture, striped umbrellas, and a rocky backdrop.
A swimming pool with lounge chairs and umbrellas, surrounded by buildings with a staircase and a view of the city skyline.
A grand lobby with a central red seating area, a staircase, and a high ceiling with skylights.
A historic building with multiple balconies and a courtyard with palm trees.

5. Grand Hotel Villa Politi

Grand Hotel Villa Politi
Grottasanta
France
abdulrahman
$148 nightly
$168 total
Sep 6 - Sep 7
Total with taxes and fees
Grand Hotel Villa Politi
A woman holding a wine glass on a balcony overlooking a street with historic buildings and a clock tower.
A building with three balconies, a central entrance with an archway, and a sign indicating it is a small luxury hotel.
A bar with a stone ceiling, a marble countertop, and shelves stocked with liquor bottles.
A grand lobby with arched ceilings, marble columns, a chandelier, and a reception desk.

6. Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection
Ortigia
United States
Victor
$256 nightly
$293 total
Aug 31 - Sep 1
Total with taxes and fees
Palazzo Artemide - VRetreats, SLH Collection
A historic building with ornate balconies, a grand entrance, and flags of the European Union and Italy.
A spacious living room with a large sofa, two armchairs, a dining area with a table and chairs, and a kitchen in the background.
A grand staircase with ornate metal railings and red carpeted steps leading to a balcony area with arched doorways and a checkered floor.
A buffet with various food items and condiments.

7. Grande Albergo Alfeo

Grande Albergo Alfeo
Santa Lucia
Australia
Janet
$114 nightly
$130 total
Sep 27 - Sep 28
Total with taxes and fees
Grande Albergo Alfeo
A spacious restaurant with high wooden ceilings and large windows.
A hotel reception area with a reception desk, a large screen displaying information, and two potted plants.
A hotel with a prominent sign reading "Mercure Hotel" and a modern facade with horizontal blue lighting.

8. Mercure Siracusa Prometeo

Mercure Siracusa Prometeo
Neapolis
$156 nightly
$189 total
Sep 28 - Sep 29
Total with taxes and fees
Mercure Siracusa Prometeo
A swimming pool with a curved edge, surrounded by lounge chairs and umbrellas, with buildings and palm trees in the background.
A hotel room with a neatly made bed, a bedside lamp, and a window with curtains.
A view through a window of a landscape with trees and a clear sky.
An aerial view of a coastal residential area with a row of houses, a swimming pool, and a clear view of the ocean.

9. Residence Archimede

Residence Archimede
Syracuse
United States
Anthony
$139 nightly
$154 total
Sep 8 - Sep 9
Total with taxes and fees
Residence Archimede
A nighttime pool area with lounge chairs and umbrellas, surrounded by palm trees and a building with balconies.
A buffet with various fruits and pastries.
A modern multi-story hotel with a central atrium, glass railings, and a well-maintained lawn.
An outdoor covered patio area with tables and chairs, a stone wall, and a palm tree.

10. Eureka Palace Hotel Spa

Eureka Palace Hotel Spa
Syracuse
Ireland
Sharon
$90 nightly
$103 total
Sep 28 - Sep 29
Total with taxes and fees
Eureka Palace Hotel Spa
A poolside breakfast setup with a newspaper, fruit bowl, juice, and coffee.
A spacious living area with a modern design, featuring a sofa set, a coffee table, and a bookshelf.
A modern dining area with multiple tables and chairs, a kitchen in the background, and decorative plants.
The exterior of Albatros Hotel with a modern design, featuring a prominent sign, a well-lit entrance, and landscaped surroundings.

11. Albatros Hotel

Albatros Hotel
Syracuse
United Kingdom
lynda
$106 nightly
$121 total
Sep 6 - Sep 7
Total with taxes and fees
Albatros Hotel
A riverside walkway with people walking and sitting, overlooking a body of water.
A buffet with various food items, including pastries, fruits, and beverages.
A view from an open window overlooking a body of water with a distant shoreline.
A stone staircase with a large urn on the landing, leading to a balcony with a metal railing overlooking the sea.

12. Charme Hotel Henry's House

Charme Hotel Henry's House
Ortigia
United States
Komal
$326 nightly
$371 total
Sep 2 - Sep 3
Total with taxes and fees
Charme Hotel Henry's House
A beach with white umbrellas and lounge chairs arranged in rows.
A spacious indoor area with high ceilings and large windows, featuring multiple seating arrangements and a modern design.
An aerial view of a resort with two swimming pools, a beach, and a coastal backdrop.
A wooden deck with sun loungers and umbrellas overlooking a calm sea.

13. VOI Arenella Resort

VOI Arenella Resort
Syracuse
United States
Frank
VOI Arenella Resort
A swimming pool with lounge chairs and umbrellas, surrounded by buildings with arched windows and palm trees.
A dining area with multiple tables and chairs, a variety of wine bottles on display, and a large window providing natural light.
A hotel with a courtyard featuring outdoor seating and umbrellas, surrounded by palm trees and a well-maintained lawn.
A modern reception area with a black reception desk, blue and yellow chairs, and a large wall clock.

14. Hotel Relax

Hotel Relax
Epipoli
Italy
marselli
$157 nightly
$179 total
Aug 30 - Aug 31
Total with taxes and fees
Hotel Relax
A hotel room with a large bed, a chair, a small table, and a chandelier.
A modern bedroom with a white bed, two bedside tables with lamps, and a chandelier.
A modern living room with a sofa, two side tables, a chandelier, and a painting on the wall.
A dining area with a wooden table and chairs, a potted plant, and a tiled floor with a geometric pattern.

15. Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
Santa Lucia
Australia
Alan
$104 nightly
$119 total
Sep 8 - Sep 9
Total with taxes and fees
Hotel Palazzo Cavalieri
A clear view of a beach with rocky formations in the water.
A garden pathway leading to a sign that reads "Rooms Beach."
A table set with a plate of food, a glass of orange juice, a glass of red drink, a white vase, and a cup.
A table set with various foods and drinks, including a bottle of champagne, plates of appetizers, and glasses of water and juice, by a poolside.

16. Hotel Villamare

Hotel Villamare
Syracuse
United Kingdom
Ceri
$207 nightly
$236 total
Sep 27 - Sep 28
Total with taxes and fees
Hotel Villamare
A poolside area with lounge chairs, a rocky structure with a fishing net, and a small lighthouse model.
A modern bedroom with a unique geometric light design on the headboard, a neatly made bed, and a bedside table with a small plant.
A spacious outdoor area with a sandy floor, a covered seating area, and a building with multiple doors and windows.
A spacious dining area with high ceilings and arched doorways, featuring white furniture and a modern design.

17. Addauro Resort

Addauro Resort
Syracuse
United Kingdom
avi
$104 nightly
$119 total
Sep 13 - Sep 14
Total with taxes and fees
Addauro Resort
A hotel entrance with a name sign, a potted plant, and a staircase.
A hotel room with a bed, a desk, a chair, a dining table, and a painting on the wall.
A hotel room with a bed, a desk with a laptop, a chair, a sofa, and a painting on the wall.
A modern bar area with a central counter, bar stools, and a coffee machine.

18. Hotel Panorama

Hotel Panorama
Neapolis
United States
rosario
$104 nightly
$119 total
Sep 2 - Sep 3
Total with taxes and fees
Hotel Panorama
A swimming pool with a tiled deck, a covered seating area with tables and chairs, and a building with a green roof in the background.
A two-story building with a flat roof, a balcony on the second floor, and a paved driveway leading to the entrance.
An outdoor dining area with round tables and chairs, a pool, and a view of a building in the background.
A breakfast setup with a table, chairs, and a basket of bread.

19. Villa Fanusa

Villa Fanusa
Syracuse
United Kingdom
J
$104 nightly
$118 total
Sep 7 - Sep 8
Total with taxes and fees
Villa Fanusa

20. Aretusa Palace Hotel

Aretusa Palace Hotel
Syracuse
Italy
Vincenzo
Aretusa Palace Hotel
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Syracuse.
Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection

Via Riva Nazario Sauro Syracuse SR
$406 nightly
$458 total
Aug 29 - Aug 30
Total with taxes and fees
9.2/10 Wonderful! (273 reviews)
Ortea Palace Hotel, Sicily, Autograph Collection
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

Viale Mazzini, 12 Syracuse SR
$322 nightly
$366 total
Aug 29 - Aug 30
Total with taxes and fees
9/10 Wonderful! (620 reviews)
Grand Hotel Ortigia Siracusa
Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Passeggio Adorno 10/12 Syracuse SR
$628 nightly
$702 total
Sep 12 - Sep 13
Total with taxes and fees
Grand Hotel Des Ètrangers - The Leading Hotels of the World
Still don't see what you're looking for?
See all properties in Syracuse.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Syracuse

Ancient Greek ruins in the Archaeological Park include the impressive Teatro Greco where summer performances still take place. Wander through Ortygia's narrow streets to discover the Duomo, built around a former Greek temple with columns still visible from inside.

See all hotels in Syracuse
An ancient amphitheater with stone ruins and a grassy field.

Top Syracuse Hotel Reviews

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

10/10 Excellent
"The hotel was very well located, offered 4 bicycles for use in town, andbfacilitatee seamless valet parking for our rented vehicle. The breakfasts"
Alfred 3-night trip
Posted 1 hour ago
Algila' Ortigia Charme Hotel
Dolce by Wyndham Siracusa I Monasteri Golf & Spa

Dolce by Wyndham Siracusa I Monasteri Golf & Spa

10/10 Excellent
"Beautiful room and friendly service."
Myrnalyn 2-night trip
Posted 2 hours ago
Dolce by Wyndham Siracusa I Monasteri Golf & Spa
Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection

10/10 Excellent
"We liked the location and the high quality of the hotel. Bedroom a little small but not a major problem."
John and Stephanie 2-night trip
Posted 6 hours ago
Palazzo Artemide - VRetreats, SLH Collection
Hotel Parco delle Fontane

Hotel Parco delle Fontane

10/10 Excellent
"Please clarify the specific procedures or instructions for gaining access to the facility, particularly regarding the address displayed at the gate."
Salvatore 1-night trip
Posted 3 days ago
Hotel Parco delle Fontane
Grande Albergo Alfeo

Grande Albergo Alfeo

10/10 Excellent
"Great spot in Siracusa and easy walk into Ortigia. The staff was friendly and Alessandro was a great help to us and answered our questions in English and Italian. Plus who can resist the refreshingly delicious free granita."
Elizabeth 3-night trip
Posted 4 days ago
Grande Albergo Alfeo
UNA Hotels One Siracusa Wellness & SPA

UNA Hotels One Siracusa Wellness & SPA

10/10 Excellent
"It’s a really beautiful hotel. Great staff, great food, AC works, beautiful spa. It’s in central place but not in the midst of all the chaos at the same time!"
Tanasha 2-night trip
Posted 2 months ago
UNA Hotels One Siracusa Wellness & SPA

Find out more about Syracuse

The outset of any holiday gets started with picking a location. Syracuse is a popular option with tourists because of everything it offers. Location is everything, but that accounts for more than the area you are flying into. Now that you have got a feeling for this city, it's time you to get to know your residence for the next several days.

Properties as Scenic as the City

Syracuse saw its fair share of visitors in the last year. Expedia's review section features tips and tricks on which accommodation will satisfy your desires for a wonderful vacation. The resorts found here aim to make your stay as gratifying as your days and nights hanging out in Syracuse. These hotels aim to make the grounds and facilities welcoming during your stay. You won't have to search long for to keep up with your exercise schedule, an invigorating spa treatment, or nice dinner.

Rooms have been designed to keep you as comfortable as possible, with amenities like ultra-comfortable bedding, designer bathroom products, and in-room coffee or tea. So, lay back and relax. Moreover, if you find that you're need of anything further, you can rest assured the staff will do their best to ensure you remain satisfied during your time. These properties are so lovely that you'll regret the day you have to check-out.

Book a 4-Star Hotel in Syracuse Today!

A holiday to Syracuse should be one where you won't have to concern yourself about the little things. With Expedia, you can get great deals on world-class accommodations to take your trip to the next level.

Frequently asked questions

What are the best 4-star hotels in Syracuse?
Look forward to 4-star hotel comfort at Algila Ortigia Charme Hotel. Rated highly by many of our guests, it comes with concierge services and room service. Also take a look at Hotel Roma. Premium bedding and concierge services help make this retreat another popular pick in Syracuse.
How much does it cost to stay in a 4-star hotel in Syracuse?
With Expedia's sort and search filters, locking in a superb deal on a 4-star hotel in Syracuse just got simpler. Start by keying in your chosen travel dates and length of your trip. Then sort the results by price and pick the option that best suits your budget and style.
  • Search for the lowest price from $366
What's the difference between 5-star and 4-star hotels in Syracuse?
Offering an inviting traveler experience and upscale décor, 4-star hotels are a fabulous option for your Syracuse vacation. These kinds of accommodations generally come with lots of handy amenities that make it simple to kick back and relax — think complimentary bathrobes, gyms and pools. Or live in the lap of luxury at a 5-star hotel designed to spoil you with high-end perks and amenities. A personalized service, oversized bathrooms and world-class dining are typically featured at these plush retreats.

Explore a world of travel with Expedia