Title: The Best 5 Star Hotels in Tupelo, MS from $133 | Expedia.com [Tupelo Travel Guide](https://expedia.com/Tupelo.dx6058686)[Hotels in Tupelo](https://expedia.com/Tupelo-Hotels.d6058686.Travel-Guide-Hotels)[Vacation Rentals in Tupelo](https://expedia.com/Tupelo-Vacation-Rentals.d6058686.Travel-Guide-VacationRentals)[Flights to Tupelo](https://expedia.com/Cheap-Flights-To-Tupelo.d6058686.Travel-Guide-Flights)[Car Rentals in Tupelo](https://expedia.com/Car-Rentals-In-Tupelo.d6058686.Car-Rental-Guide)[Tupelo Vacation Packages](https://expedia.com/Tupelo.d6058686.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Tupelo 5 Star Hotels Tonight [Mar 13 - Mar 14](https://www.expedia.com/Hotel-Search?regionId=6058686&startDate=2026-03-13&endDate=2026-03-14&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 14 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=6058686&startDate=2026-03-14&endDate=2026-03-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=6058686&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=6058686&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Tupelo-Hotels.s50-0-d6058686.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Tupelo-Hotels.s50-0-d6058686.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Tupelo. ![Graduate by Hilton Oxford](https://images.trvl-media.com/lodging/1000000/20000/16600/16565/c6bcd6ee_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Graduate by Hilton Oxford 400 North Lamar Boulevard Oxford MS $122 nightly $133 total Mar 30 - Mar 31 Total with taxes and fees 9/10 Wonderful! (1,000 reviews) [](https://expedia.com/Oxford-Hotels-Graduate-Oxford.h16565.Hotel-Information) ![ The Oliver Hotel, Oxford](https://images.trvl-media.com/lodging/13000000/12900000/12894500/12894458/5c7233d3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Oliver Hotel, Oxford 425 S Lamar Blvd Oxford MS $149 nightly $162 total Apr 1 - Apr 2 Total with taxes and fees 9.6/10 Exceptional! (340 reviews) [](https://expedia.com/Oxford-Hotels-Chancellors-House.h12894458.Hotel-Information) ![Oxford Condo ~ 1 Mi to Ole Miss + The Grove!](https://images.trvl-media.com/lodging/94000000/93210000/93202000/93201933/069fb371_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Oxford Condo \~ 1 Mi to Ole Miss + The Grove! Oxford MS [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F27%2F2026&endDate=3%2F28%2F2026&selected=93201933&PinnedHotelID=93201933&HadPinnedHotel=true®ionId=6058686) [](https://expedia.com/Oxford-Hotels-Oxford-Condo-1-Mi-To-Ole-Miss-The-Grove.h93201933.Hotel-Information) Still don't see what you're looking for? [See all properties in Tupelo.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F14%2F2026&endDate=3%2F15%2F2026®ionId=6058686&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F14%2F2026&endDate=3%2F15%2F2026®ionId=6058686&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F14%2F2026&endDate=3%2F15%2F2026®ionId=6058686&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F14%2F2026&endDate=3%2F15%2F2026®ionId=6058686&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F14%2F2026&endDate=3%2F15%2F2026®ionId=6058686&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F14%2F2026&endDate=3%2F15%2F2026®ionId=6058686&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Tupelo and related destinations - Tupelo - St. Joseph - Tullahoma - Hagerstown - Meridian Visit Elvis Presley's humble birthplace home and learn how this small town shaped the King's early years. Explore the Natchez Trace Parkway's scenic trails and stop at the automobile museum where vintage cars gleam under spotlights. [See all hotels in Tupelo](https://www.expedia.com/Hotel-Search?startDate=2026-03-27&endDate=2026-03-28&adults=2®ionId=6058686) ![Tupelo, Mississippi City Hall, is a government building in Tupelo.](https://images.trvl-media.com/place/6058686/ae33cefe-d2f1-4bbf-97ff-5fee4a9debb4.jpg?impolicy=fcrop&w=900&h=599&p=1&q=high) ## Top Tupelo Hotel Reviews ## Find out more about Tupelo Why not request complete opulence during your trip to Tupelo? After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Tupelo so popular in the last year. There's no reason to delay a getaway to Tupelo any longer. Furthermore, you'll find that these hotels are kept in fantastic condition and provide a fine place to lay your head at night. Book one of Expedia's luxurious 5-star hotels in Tupelo and get ready to be pampered like never before. You deserve an outstanding getaway. ### Book the Best Tupelo 5-Star Hotels Don't be afraid to be pampered during your trip, along with the best conditions. Top-notch service, delicious meals, and one-on-one attention are all at your fingertips. You're sure to find exactly the accommodation you need. We should also mention, the hotels in this area receive fantastic marks for guest services, so you know you'll want for nothing during your getaway. How do you want to relax? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A reflexology treatment that will leave you feeling like a million bucks? Butler services? No matter what you want on a perfect getaway, you're bound to find it here. Want to see for yourself? Then explore the 252 reviews various guests have left on Expedia and get to know these places. Yearning for experiences outside your hotel room? You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Tupelo are the perfect place to rest up after an exciting day. ### Make Your Escape The results are in, and Tupelo 5-star hotels are the place to be when you book your next vacation. Additionally, these accommodations are highly rated -- 90% of visitors recommended 5-star hotels in Tupelo! Expedia can help you land a great deal on accommodation. Your great getaway is just a mouse-click away. Select one of our Tupelo 5-star hotels today and decompress in complete comfort tomorrow. ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Tupelo? > - Search for the lowest price per night from $133 ### What makes a hotel 5 stars in Tupelo? ### Are there any 5-star all-inclusive resorts in Tupelo? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [Vacation Homes in Lee County ](https://www.expedia.com/Lee-County-Private-Vacation-Homes.d553248635976433082-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Hotels near BancorpSouth Arena ](https://www.expedia.com/BancorpSouth-Arena-Hotels.0-l6092629-0.Travel-Guide-Filter-Hotels) - [Hotels near North Mississippi Medical Center ](https://www.expedia.com/North-Mississippi-Medical-Center-Hotels.0-l6140198-0.Travel-Guide-Filter-Hotels) - [Hotels near Elvis Presley Center ](https://www.expedia.com/Elvis-Presley-Center-Hotels.0-l553248621532655101-0.Travel-Guide-Filter-Hotels) - 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[Flights from Augusta (AGS) to Tupelo (TUP) ](https://www.expedia.com/lp/flights/ags/tup/augusta-to-tupelo) - [Flights from St. Petersburg (PIE) to Tupelo (TUP) ](https://www.expedia.com/lp/flights/pie/tup/st-petersburg-to-tupelo) - [Flights from Palm Springs (PSP) to Tupelo (TUP) ](https://www.expedia.com/lp/flights/psp/tup/palm-springs-to-tupelo) - [Flights from San Diego (SAN) to Tupelo (TUP) ](https://www.expedia.com/lp/flights/san/tup/san-diego-to-tupelo) - [Flights from Norfolk (ORF) to Tupelo (TUP) ](https://www.expedia.com/lp/flights/orf/tup/norfolk-to-tupelo) - [Flights from West Palm Beach (PBI) to Tupelo (TUP) ](https://www.expedia.com/lp/flights/pbi/tup/west-palm-beach-to-tupelo) - [Bancorpsouth Arena ](https://www.expedia.com/BancorpSouth-Arena-Tupelo.d6092629.Vacation-Attraction) - [North Mississippi Medical Center ](https://www.expedia.com/North-Mississippi-Medical-Center-Tupelo.d6140198.Vacation-Attraction) - [Elvis Presley Lake and Campground ](https://www.expedia.com/Elvis-Presley-Lake-And-Campground-Tupelo.d553248621532655103.Vacation-Attraction) - [Ballard Park ](https://www.expedia.com/Ballard-Park-Tupelo.d553248621532655097.Vacation-Attraction) - [Oren Dunn City Museum ](https://www.expedia.com/Oren-Dunn-City-Museum-Tupelo.d553248621532655096.Vacation-Attraction) - [Car rentals near BancorpSouth Arena ](https://www.expedia.com/Car-Rentals-In-BancorpSouth-Arena.d6092629.Car-Rental-Guide) - [Car rentals near Elvis Presley Center ](https://www.expedia.com/Car-Rentals-In-Elvis-Presley-Center.d553248621532655101.Car-Rental-Guide) - [Car rentals near Tupelo National Battlefield ](https://www.expedia.com/Car-Rentals-In-Tupelo-National-Battlefield.d6092633.Car-Rental-Guide) - [Car rental Tupelo Airport (TUP) ](https://www.expedia.com/Car-Rentals-In-Tupelo-Regional.d6032641.Car-Rental-Guide)