Carlisle Vacations from $474

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Your Carlisle Vacation

Cuisine, art, entertainment and more … It's all waiting for you with a Carlisle vacation package. And with the ability to customize your city break, it's guaranteed to be one you won't forget. If seeing the sights is on your list of things to do during your trip to Carlisle, stop by popular attractions such as Summerset Winery. No matter your travel plans or budget, organizing a tailored Carlisle vacation is a piece of cake with Expedia.

The Latest Carlisle vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
Downtown Des Moines
Price was $552, price is now $474 per person
$474
per person
May 16 - May 18
found 1 day ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
9.6/10 Exceptional! (1,037 reviews)
Excellent hotel and service. Great restaurant and speak easy!

Reviewed on Feb 21, 2026

Hilton Des Moines Downtown

Hilton Des Moines Downtown

3.5 out of 5
Downtown Des Moines
Price was $1,051, price is now $852 per person
$852
per person
Apr 12 - Apr 18
found 12 hours ago
Roundtrip non-stop flight included
Portland (PDX) to Des Moines (DSM)
9/10 Wonderful! (1,000 reviews)
Clean room. Friendly staff.

Reviewed on Feb 8, 2026

My Place Hotel - Ankeny/ Des Moines, IA

My Place Hotel - Ankeny/ Des Moines, IA

3 out of 5
Price was $609, price is now $528 per person
$528
per person
Apr 12 - Apr 18
found 12 hours ago
Roundtrip non-stop flight included
Portland (PDX) to Des Moines (DSM)
9/10 Wonderful! (758 reviews)
Friendly staff & a clean, welcoming facility! We’ll definitely be staying here again.

Reviewed on Jan 23, 2026

Hyatt Place Altoona/Des Moines

Hyatt Place Altoona/Des Moines

3 out of 5
Price was $803, price is now $707 per person
$707
per person
Apr 12 - Apr 18
found 12 hours ago
Roundtrip non-stop flight included
Portland (PDX) to Des Moines (DSM)
9.4/10 Exceptional! (842 reviews)
Very clean, staff was amazing!

Reviewed on Jan 11, 2026

My Place Hotel - Altoona/Des Moines, IA

My Place Hotel - Altoona/Des Moines, IA

3 out of 5
Price was $609, price is now $539 per person
$539
per person
Apr 12 - Apr 18
found 12 hours ago
Roundtrip non-stop flight included
Portland (PDX) to Des Moines (DSM)
8.8/10 Excellent! (932 reviews)
The staff member was courteous though she was on a phone call on speaker phone when I arrived and throughout my check in process. Everything was clean and the room was as expected. I was only there for one night so I can’t speak to house keeping services.

Reviewed on Feb 17, 2026

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Carlisle Hotel Deals

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $161 total per night from Mar 1 to Mar 2
$161 total
Mar 1 - Mar 2
Total with taxes and fees
9.4/10 Exceptional! (1,082 reviews)
Comfortable beds, clean, the most well dressed and courteous staff. I love the character this hotel has. It’s gorgeous.

Reviewed on Feb 16, 2026

Hotel Fort Des Moines, Curio Collection by Hilton
Sonesta Simply Suites Des Moines

Sonesta Simply Suites Des Moines

2 out of 5
7625 Office Plaza Dr N West Des Moines IA
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $89 total per night from Feb 23 to Feb 24
$89 total
Feb 23 - Feb 24
Total with taxes and fees
8.2/10 Very Good! (983 reviews)
Very clean Nice staff

Reviewed on Feb 16, 2026

Sonesta Simply Suites Des Moines
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $100 total per night from Feb 25 to Feb 26
$100 total
Feb 25 - Feb 26
Total with taxes and fees
9.2/10 Wonderful! (1,006 reviews)
Nice experience

Reviewed on Feb 17, 2026

Home2 Suites by Hilton Des Moines at Drake University
See all 851 properties in Carlisle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Carlisle Vacation Packages

Carlisle Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Des Moines Intl. Airport (DSM)
Population
4,200
Top Sights
Summerset Winery, Indianola Pickard Sports Complex and Des Moines Metro Opera

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Frequently asked questions

How much does a Carlisle vacation package cost?
You can pick up a vacation package to this popular destination from $474 on Expedia. However, how much your vacation to Carlisle costs will depend on the length of stay, hotel choice and season.
What are the cheapest months to go to Carlisle?
March, August and December are great times to look for cheap Carlisle vacation packages. Choosing to travel in less busy months means you can generally find lower prices on flights and hotels.
How many days is enough for Carlisle?
The ideal length for your Carlisle vacation depends on what you'd like to do and see. Typically, a handful of days to a week will give you enough time to check out all the top sights and discover some hidden gems along the way.
How to find the best Carlisle package deals?
Begin your search for a Carlisle package deal by entering your destination and preferred trip dates under our "Packages" tab. Then select some filters, like "Guest rating" and "Property type," to fine-tune the results to your exact needs. You can also sort by "Package discount" and discover offers that come with huge savings. If you don't find the ideal Carlisle package deal right away, simply switch up your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Carlisle adventure off to a flying start.
Is it cheaper to book a Carlisle vacation as a package?
You can enjoy significant savings on your Carlisle escape by booking a customized vacation package. Check the "Package" heading, then enter your travel dates and destination to view some great hotel prices and airfares. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a vacation package to Carlisle?
If you're planning a spur-of-the-moment Carlisle getaway, check out our last-minute deals that can be booked up to a week before you go. Prefer not to wait until the last minute? You can land sensational deals on your hotels and flights by booking ahead.
Does Expedia offer Book Now, Pay Later Carlisle vacation packages?
If you're like us, you love traveling the world but don't love the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the total cost of your Carlisle trip across 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure great vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.