Resorts & Hotels with Spas in South Carolina from $97
Upfront pricing
Our total price for your stay includes taxes and fees
Treat yourself
Save 10% or more on over 100,000 hotels worldwide with Member Prices
Be picky
Search almost a million properties worldwide
Check availability on South Carolina Resorts & Hotels with Spas
Pick from 1506 South Carolina Resorts & Hotels with Spas with updated room rates, reviews, and availability. Most hotels are fully refundable.
Our top choices for South Carolina hotels with a spa

Montage Palmetto Bluff
Montage Palmetto Bluff
9.6 out of 10, Exceptional, (236)
$561 nightly
The price is $617
Sep 2 - Sep 3
Total includes taxes and fees

Hotel Bennett
Hotel Bennett
9.6 out of 10, Exceptional, (916)
$401 nightly
The price is $457
Sep 2 - Sep 3
Total includes taxes and fees

The Charleston Place
The Charleston Place
9.6 out of 10, Exceptional, (1004)
$352 nightly
The price is $401
Aug 24 - Aug 25
Total includes taxes and fees

Kingston Plantation Condos
Kingston Plantation Condos
7.8 out of 10, Good, (1010)
$145 nightly
The price is $163
Sep 1 - Sep 2
Total includes taxes and fees

Marriott's OceanWatch at Grande Dunes
Marriott's OceanWatch at Grande Dunes
9.4 out of 10, Exceptional, (468)
$589 nightly
The price is $666
Sep 1 - Sep 2
Total includes taxes and fees

La Quinta Inn & Suites by Wyndham Myrtle Beach - N Kings Hwy
La Quinta Inn & Suites by Wyndham Myrtle Beach - N Kings Hwy
8.2 out of 10, Very Good, (2279)
$86 nightly
The price is $97
Sep 1 - Sep 2
Total includes taxes and fees

Hyatt House Charleston/Historic District
Hyatt House Charleston/Historic District
8.6 out of 10, Excellent, (1001)
$175 nightly
The price is $200
Aug 24 - Aug 25
Total includes taxes and fees

Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference Center
8.8 out of 10, Excellent, (1008)
$106 nightly
The price is $117
Aug 31 - Sep 1
Total includes taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top South Carolina Hotel Reviews

Compass Cove Resort
10/10 Excellent
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Columbia Hotels
- Cheap Hotels in Columbia
- Luxury Hotels in Columbia
- Pet-friendly Hotels in Columbia
- Hotels near Downtown Columbia
- Hotels with Restaurants in Downtown Columbia
- Hotels with an Indoor Pool in Columbia
- Hotels with a View in Downtown Columbia
- Hotels with Free Breakfast in Downtown Columbia
- Hotels with Connecting Rooms in Downtown Columbia
- Historic Hotels in Downtown Columbia
- Hotels with Room Service in Downtown Columbia
- Hotels with Hot Tubs in Downtown Columbia
- Hotels with Suites in Downtown Columbia
- Luxury Hotels in Downtown Columbia
- Hotels with Bars in Downtown Columbia
- Pet-friendly Hotels in Downtown Columbia
- Hotels with an Outdoor Pool in Downtown Columbia
- Hotels with Free Parking in Downtown Columbia
- Hotels with a Gym in Downtown Columbia
- Hotels with Kitchenettes in Downtown Columbia
- Hotels with an Indoor Pool in Downtown Columbia
- Hotels with Balconies in Downtown Columbia
- Hotels with Laundry Facilities in Downtown Columbia
- Resorts & Hotels with Spas in Downtown Columbia
- Honeymoon Resorts & in Downtown Columbia
- Hotel Wedding Venues Hotels in Downtown Columbia
- Hotels with a Pool in Downtown Columbia
- Cheap Hotels in Downtown Columbia
- Hotels with Suites in Columbia
- Hotels with Balconies in Columbia
- Hotels with Hot Tubs in Columbia
- Resorts & Hotels with Spas in Columbia
- Hotels with Free Airport Shuttle in Columbia
- Hotels with smoking rooms in Columbia
- Hotels with Connecting Rooms in Columbia
- Honeymoon Resorts & in Columbia
- Hotels with Kitchenettes in Columbia
- Boutique Hotels in Columbia
- Hotels with Early Check-in in Columbia
- Hotel Wedding Venues Hotels in Columbia
- Hotels with Bars in Columbia
- Hotels with Restaurants in Columbia
- Hotels with Free Breakfast in Columbia
- Hotels with a Gym in Columbia
- Beach Hotels in Columbia
- Romantic Hotels in Columbia
- Hotels with an Outdoor Pool in Columbia
- Casino Hotels in Columbia
- Hotels with an Indoor Pool in The Vista
- Hotels with Free Parking in The Vista
- Luxury Hotels in The Vista
- Hotels with an Outdoor Pool in The Vista
- Hotel Wedding Venues Hotels in The Vista
- Extended Stay Hotels in Columbia
- Family Hotels in Columbia
- Historic Hotels in Columbia
- Adults Only Resorts & in Columbia
- Hotels with Room Service in Columbia
- Hotels on the Lake in Columbia
- Golf Hotels in Columbia
- Hotels with Laundry Facilities in Columbia
- Hotels with Free Parking in Columbia
- Hotels with a Pool in Columbia
- Hotels with Fireplaces in Columbia
- Business Hotels in Columbia
- Hotels with a View in Columbia
- Non-Smoking Hotels in Columbia
- Quiet Resorts & in Columbia
- Hotels with Tennis Courts in Columbia
- Hotels & Resorts for Couples in Columbia
- Hotel with a Concierge Hotels in Columbia
- Hotels with Air Conditioning in Columbia
- Green Hotels in Columbia
- Fishing Resorts & in Columbia
- Hotels near University of South Carolina
- 5 Star Hotels in Downtown Columbia
- 3 Star Hotels in Downtown Columbia
- Hotels near South Carolina State House
- Hotels near Trinity Episcopal Cathedral
- Hotels near Town Theatre
- Hotels near Colonial Life Arena
- Motels in Columbia
- Hotels near Columbia Metropolitan Convention Center
- The Vista Hotels
- 5 Star Hotels in Columbia

















































