Effingham Vacation Rentals

Check prices for these dates

In two weeks
Jun 5 - Jun 7
In two months
Jul 17 - Jul 19
In three months
Aug 14 - Aug 16
In four months
Sep 11 - Sep 13

Our top choices for Effingham vacation rentals

1 bedroom, iron/ironing board, travel crib, free WiFi

Charming Cottage with easy access to local attractions-pet and kid friendly

Charming Cottage with easy access to local attractions-pet and kid friendly
Sellers
9.6 out of 10, Exceptional, (26 reviews)
"A great place to stay with our two dogs. We will be back again soon."
United States
Marianne P.
$180 nightly
The price is $196
May 25 - May 26
Total with taxes and fees
Charming Cottage with easy access to local attractions-pet and kid friendly
Microwave, oven, stovetop, dishwasher

Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views

Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views
Hartsville
10.0 out of 10, Exceptional, (12 reviews)
"Very clean, stayed here for work. Would definitely book again if in the area. "
United States
Kacey
$142 nightly
The price is $155
May 24 - May 25
Total with taxes and fees
Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views
Interior

Walking distance from one of South Carolina's top Medical centers.

Walking distance from one of South Carolina's top Medical centers.
Florence
9.8 out of 10, Exceptional, (52 reviews)
"Our third time staying at this home and always have had a great experience. Such a comfy home and very well stocked. Great hosts!"
United States
Kelly W.
$205 nightly
The price is $230
May 25 - May 26
Total with taxes and fees
Walking distance from one of South Carolina's top Medical centers.
Interior

Secret SC Cabin on 100 acres Hot Tub Large Pond

Secret SC Cabin on 100 acres Hot Tub Large Pond
Marion
9.6 out of 10, Exceptional, (184 reviews)
"Great location and house and the host was excellent!"
United States
Josh R.
$432 nightly
The price is $470
May 24 - May 25
Total with taxes and fees
Secret SC Cabin on 100 acres Hot Tub Large Pond
Dining

Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!

Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!
Marion
9.0 out of 10, Wonderful, (6 reviews)
"It was a great place. "
United States
Cindy N.
$548 nightly
The price is $597
May 25 - May 26
Total with taxes and fees
Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!
Fridge, microwave, oven, stovetop

The Pinecone Retreat - Only 1 mile from i95

The Pinecone Retreat - Only 1 mile from i95
Latta
10.0 out of 10, Exceptional, (2 reviews)
"So comfy and cozy but plenty of room for our family of four!"
United States
Nita S.
$130 nightly
The price is $142
May 24 - May 25
Total with taxes and fees
The Pinecone Retreat - Only 1 mile from i95
Interior

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Florence
10.0 out of 10, Exceptional, (54 reviews)
"Beautiful home and the hosts were so accommodating!!"
United States
Judith S.
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Dining

Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.

Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.
Florence
8.6 out of 10, Excellent, (4 reviews)
"Convenient location"
United States
Bonney W.
$453 nightly
The price is $507
Jun 15 - Jun 16
Total with taxes and fees
Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.
Interior

Perfect Stop • Near I-95, Downtown & Civic Center and Darlington

Perfect Stop • Near I-95, Downtown & Civic Center and Darlington
Florence
9.8 out of 10, Exceptional, (10 reviews)
"It was perfect! And the host was the best everrrr I loved every second I will be returning! "
United States
Kimesha C.
$251 nightly
The price is $281
May 25 - May 26
Total with taxes and fees
Perfect Stop • Near I-95, Downtown & Civic Center and Darlington
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Effingham Hotel Reviews

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

10/10 Excellent
"Nice hotel"
Vadim 1-night trip
Posted less than an hour ago
Park Inn by Radisson Florence, SC

Find out more about Effingham

Everything you need to know about Effingham vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Effingham vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Effingham vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Effingham vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Effingham. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Effingham in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $142 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Effingham rentals

At Expedia, we put the best Effingham vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Effingham rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Effingham vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Effingham. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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Frequently asked questions

Can I find vacation rentals in Effingham?

Yes, we have vacation rentals close to popular attractions in Effingham, or you can choose a more secluded option if you want a relaxing place to stay.

What are some of the best vacation rentals in Effingham?

Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.: Visitors like this Effingham vacation home rental. It has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop.

What’s there to see and do in Effingham?

While you're exploring the area, Moore Farms Botanical Garden and Palmetto Shores Lake are a couple of picturesque spots to get outside and enjoy nature. Lynches River State Park and Florence Museum are a couple of places you'll find in the larger area.

What are vacation rentals like in Effingham?

Vacation rentals are privately owned properties you can reserve for a couple days or more in Effingham. Vacation rentals offer amenities like kitchens and laundry facilities so you'll have all the conveniences of home. If you're concerned about a sanitized environment, a vacation rental can offer a sense of security away from public hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great choice for a small group gathering.