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Our top choices for Effingham hotels

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1,014 reviews)
"Friendly staff, quick check in, nice lobby"
United States
Jennifer
$107 nightly
The price is $120
Mar 1 - Mar 2
Total with taxes and fees
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Quality Inn Mullins - Marion

Quality Inn Mullins - Marion
2.5 star property
Marion
7.8 out of 10, Good, (387 reviews)
"It was ok clean would stay there again. "
United States
jeff
$98 nightly
The price is $107
Mar 7 - Mar 8
Total with taxes and fees
Quality Inn Mullins - Marion

Best Western Executive Inn

Best Western Executive Inn
2.5 star property
Latta
8.2 out of 10, Very Good, (961 reviews)
"Would definitely stay again !!!"
United States
Tracy
$102 nightly
The price is $111
Mar 3 - Mar 4
Total with taxes and fees
Best Western Executive Inn

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.2 out of 10, Wonderful, (1,239 reviews)
"The staff was friendly and the room was clean. "
United States
Camila
$97 nightly
The price is $108
Feb 25 - Feb 26
Total with taxes and fees
Comfort Inn & Suites Florence Center Area

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
9.0 out of 10, Wonderful, (1,006 reviews)
"Great location and well maintained property. "
United States
Karen
$110 nightly
The price is $123
Mar 9 - Mar 10
Total with taxes and fees
Hyatt Place Florence Downtown

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (870 reviews)
"The employees were so nice!"
United States
ron
$118 nightly
The price is $132
Mar 3 - Mar 4
Total with taxes and fees
Hampton Inn & Suites Florence-North-I-95

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2,565 reviews)
"I nice place to stay, very quiet, good breakfast, nice staff, spotless room. "
United States
Timothy
$67 nightly
The price is $75
Feb 25 - Feb 26
Total with taxes and fees
Howard Johnson by Wyndham Florence

Super 8 by Wyndham Florence

Super 8 by Wyndham Florence
2.0 star property
Florence
7.0 out of 10, Good, (1,002 reviews)
"Perfect overnight spot"
United States
Martin
$57 nightly
The price is $63
Mar 27 - Mar 28
Total with taxes and fees
Super 8 by Wyndham Florence

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2,255 reviews)
"Room was clean, staff friendly, and the includes breakfast was great "
United States
Samantha
$86 nightly
The price is $96
Mar 1 - Mar 2
Total with taxes and fees
Park Inn by Radisson Florence, SC

Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.4 out of 10, Very Good, (1,002 reviews)
"We enjoyed our stay. Everything stood out Staff, Clean room and Amenities. "
United States
Marita
$101 nightly
The price is $113
Mar 3 - Mar 4
Total with taxes and fees
Tru by Hilton Florence I-95

Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG
2.5 star property
Latta
9.4 out of 10, Exceptional, (559 reviews)
"Front desk is amazing! Rooms are clean and quiet. "
United States
Kimberly
$103 nightly
The price is $112
Mar 9 - Mar 10
Total with taxes and fees
Holiday Inn Express & Suites Latta by IHG

Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
Florence
8.4 out of 10, Very Good, (1,001 reviews)
"Great accommodations and courteous staff"
United States
Leslie
$106 nightly
The price is $118
Feb 25 - Feb 26
Total with taxes and fees
Comfort Suites Florence I-95

Best Western Inn

Best Western Inn
2.5 star property
Florence
7.8 out of 10, Good, (1,006 reviews)
"Front desk staff was great and very friendly! Made for a smooth check-in!"
United States
Patric
$89 nightly
The price is $100
Feb 25 - Feb 26
Total with taxes and fees
Best Western Inn

Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
3.0 star property
Florence
9.2 out of 10, Wonderful, (588 reviews)
"Friendly staff, clean and comfortable room "
United States
craig
$105 nightly
The price is $118
Mar 8 - Mar 9
Total with taxes and fees
Fairfield Inn & Suites by Marriott Florence I-20

Budget Inn Timmonsville

Budget Inn Timmonsville
2.0 star property
Timmonsville
7.0 out of 10, Good, (327 reviews)
"Very nice, always clean and easy on off access from route 95."
United States
Debbie
$61 nightly
The price is $68
Feb 25 - Feb 26
Total with taxes and fees
Budget Inn Timmonsville

Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
Florence
8.8 out of 10, Excellent, (620 reviews)
"Special place. Great staff with an outstanding restaurant "
United States
John D
$130 nightly
The price is $146
Mar 5 - Mar 6
Total with taxes and fees
Hotel Florence, Tapestry Collection by Hilton

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (960 reviews)
"Room clean, bed good, breakfast good choices, front desk excellent"
United States
mona
$123 nightly
The price is $138
Mar 24 - Mar 25
Total with taxes and fees
Staybridge Suites Florence - Civic Center by IHG

Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North
2.0 star property
Florence
6.8 out of 10, (1,006 reviews)
"Great room and reasonable price "
United States
Hattab
$60 nightly
The price is $67
Feb 27 - Feb 28
Total with taxes and fees
Days Inn by Wyndham Florence/I-95 North

SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
3.0 star property
Florence
8.6 out of 10, Excellent, (1,008 reviews)
"Krystal was great!!"
United States
James
$97 nightly
The price is $109
Mar 1 - Mar 2
Total with taxes and fees
SpringHill Suites by Marriott Florence

Super 8 by Wyndham Florence SC I-95 North / Hwy 76

Super 8 by Wyndham Florence SC I-95 North / Hwy 76
2.0 star property
Florence
5.2 out of 10, (356 reviews)
"Room was average. Breakfast was a joke, no name cereal and coffee "
United States
Waleed
$58 nightly
The price is $65
Feb 25 - Feb 26
Total with taxes and fees
Super 8 by Wyndham Florence SC I-95 North / Hwy 76
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Effingham Hotel Reviews

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Frequently asked questions

What is the best area to stay in Effingham?
The best area to stay in Effingham is near the intersection of US-301 and I-95, as this offers the most convenient access to amenities and onward travel.

This area is primarily characterized by its array of hotels, restaurants, and gas stations, strategically located for travelers passing through or needing a stopover. You'll find most services concentrated along US-301, just off the I-95 exits. While not a tourist destination in itself, it provides all the necessary conveniences for a comfortable stay.

For solo travelers or couples on a road trip, this location is ideal. It offers quick access to the interstate, making it easy to continue your journey. The concentration of dining options, from casual eateries to sit-down restaurants, provides variety without requiring extensive travel.
When is the best time to go to Effingham?
The best time to visit Effingham, South Carolina, is during the spring (March to May) and fall (September to November) months.

These seasons offer pleasant weather with mild temperatures, ideal for enjoying outdoor activities without the intense heat and humidity of summer or the cooler, sometimes unpredictable, temperatures of winter. Spring brings blooming flora, while fall showcases colorful foliage, making for scenic drives and comfortable exploration of the local area.

For travelers who prefer warm weather and don't mind higher humidity, the summer months (June to August) are also an option. During this time, the days are long, allowing for extended outdoor enjoyment, though afternoon thunderstorms can occur.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Effingham.
How can I save on a Effingham hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Effingham hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Effingham hotel?
Prices for hotels in Effingham often vary, but you can find a great deal from $53 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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