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Our top choices for Effingham hotels

Quality Inn Mullins - Marion

Quality Inn Mullins - Marion
2.5 star property
Marion
7.6 out of 10, Good, (395 reviews)
"It was ok clean would stay there again. "
United States
jeff
$102 nightly
The price is $111
Apr 25 - Apr 26
Total with taxes and fees
Quality Inn Mullins - Marion

Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG
2.5 star property
Latta
9.4 out of 10, Exceptional, (575 reviews)
"Great visit to this site...convenient to food, gas, and the staff was so pleasant. Breakfast was very good and I would not hesitate to stay there again"
United States
Cheryl
$114 nightly
The price is $124
May 3 - May 4
Total with taxes and fees
Holiday Inn Express & Suites Latta by IHG

Best Western Executive Inn

Best Western Executive Inn
2.5 star property
Latta
8.2 out of 10, Very Good, (982 reviews)
"The staff at check in and the staff at check out was wonderful "
United States
Jackieann
$106 nightly
The price is $116
Apr 20 - Apr 21
Total with taxes and fees
Best Western Executive Inn

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2,630 reviews)
"Very comfortable room and the hotel was close to the Interstate and many good trestaurants."
United States
Charles
$67 nightly
The price is $75
Apr 26 - Apr 27
Total with taxes and fees
Howard Johnson by Wyndham Florence

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,266 reviews)
"Clean room, good breakfast...very nice overnight stay."
United States
Gerry
$101 nightly
The price is $113
May 10 - May 11
Total with taxes and fees
Comfort Inn & Suites Florence Center Area

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.0 out of 10, Very Good, (67 reviews)
"Wonderful staff and very clean room and facilities , "
United States
catherine
$93 nightly
The price is $104
Apr 20 - Apr 21
Total with taxes and fees
Spark by Hilton Florence North I-95, SC

Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
Florence
8.4 out of 10, Very Good, (1,010 reviews)
"Love the hotel. "
United States
Blaire
$104 nightly
The price is $116
May 10 - May 11
Total with taxes and fees
Comfort Suites Florence I-95

Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center
2.5 star property
Florence
7.0 out of 10, Good, (1,007 reviews)
"Clean, very quiet , staff very friendly, safe place. "
United States
María
$66 nightly
The price is $74
Apr 19 - Apr 20
Total with taxes and fees
Days Inn by Wyndham Florence Near Civic Center

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (894 reviews)
"Busy hotel. Nice rooms awesome free breakfast "
United States
Ken
$120 nightly
The price is $134
Apr 27 - Apr 28
Total with taxes and fees
Hampton Inn & Suites Florence-North-I-95

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2,265 reviews)
"Bed was comfortable and breakfast was good "
Canada
Bernard
$89 nightly
The price is $100
Apr 19 - Apr 20
Total with taxes and fees
Park Inn by Radisson Florence, SC

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
8.6 out of 10, Excellent, (76 reviews)
"Employees were very helpful and friendly. Great stay!"
United States
Jerry
$95 nightly
The price is $106
Apr 19 - Apr 20
Total with taxes and fees
Quality Inn & Suites Florence Civic Center

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1,002 reviews)
"The stay was great"
United States
Dianne
$130 nightly
The price is $146
May 3 - May 4
Total with taxes and fees
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Best Western Inn

Best Western Inn
2.5 star property
Florence
7.8 out of 10, Good, (1,005 reviews)
"Very friendly staff. The room was very spacious. "
United States
Arika
$99 nightly
The price is $111
Apr 14 - Apr 15
Total with taxes and fees
Best Western Inn

Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
Florence
8.8 out of 10, Excellent, (625 reviews)
"Nice room. Good breakfast. Interesting town"
United States
Noel
$130 nightly
The price is $146
Apr 26 - Apr 27
Total with taxes and fees
Hotel Florence, Tapestry Collection by Hilton

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
9.0 out of 10, Wonderful, (1,008 reviews)
"Great place for our stop on our way to Florida "
United States
Mark
$122 nightly
The price is $137
Apr 26 - Apr 27
Total with taxes and fees
Hyatt Place Florence Downtown

TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
Florence
9.0 out of 10, Wonderful, (801 reviews)
"Place was perfect for a short stay "
United States
Victor
$118 nightly
The price is $132
Apr 19 - Apr 20
Total with taxes and fees
TownePlace Suites by Marriott Florence

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
7.8 out of 10, Good, (1,633 reviews)
"Good hotel"
United States
Eric
$99 nightly
The price is $111
Apr 26 - Apr 27
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Florence

Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North
2.0 star property
Florence
6.6 out of 10, (1,003 reviews)
"Clean room, friendly staff and ample parking, breakfast is ok. "
United States
Romeo
$61 nightly
The price is $69
Apr 14 - Apr 15
Total with taxes and fees
Days Inn by Wyndham Florence/I-95 North

Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
3.0 star property
Florence
9.0 out of 10, Wonderful, (623 reviews)
"Great place to stay while we have long trip from FL to NY"
United States
Sergii
$118 nightly
The price is $132
Apr 19 - Apr 20
Total with taxes and fees
Fairfield Inn & Suites by Marriott Florence I-20

Super 8 by Wyndham Florence

Super 8 by Wyndham Florence
2.0 star property
Florence
7.0 out of 10, Good, (1,003 reviews)
"Perfect overnight spot"
United States
Martin
$58 nightly
The price is $65
Apr 20 - Apr 21
Total with taxes and fees
Super 8 by Wyndham Florence
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Top Effingham Hotel Reviews

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Frequently asked questions

What is the best area to stay in Effingham?
The best area to stay in Effingham is near the intersection of US-301 and I-95, as this offers the most convenient access to amenities and onward travel.

This area is primarily characterized by its array of hotels, restaurants, and gas stations, strategically located for travelers passing through or needing a stopover. You'll find most services concentrated along US-301, just off the I-95 exits. While not a tourist destination in itself, it provides all the necessary conveniences for a comfortable stay.

For solo travelers or couples on a road trip, this location is ideal. It offers quick access to the interstate, making it easy to continue your journey. The concentration of dining options, from casual eateries to sit-down restaurants, provides variety without requiring extensive travel.
When is the best time to go to Effingham?
The best time to visit Effingham, South Carolina, is during the spring (March to May) and fall (September to November) months.

These seasons offer pleasant weather with mild temperatures, ideal for enjoying outdoor activities without the intense heat and humidity of summer or the cooler, sometimes unpredictable, temperatures of winter. Spring brings blooming flora, while fall showcases colorful foliage, making for scenic drives and comfortable exploration of the local area.

For travelers who prefer warm weather and don't mind higher humidity, the summer months (June to August) are also an option. During this time, the days are long, allowing for extended outdoor enjoyment, though afternoon thunderstorms can occur.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Effingham.
How can I save on a Effingham hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Effingham hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Effingham hotel?
Prices for hotels in Effingham often vary, but you can find a great deal from $63 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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