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Our top choices for Effingham hotels

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
9.0 out of 10, Wonderful, (1,004 reviews)
"Great location and well maintained property. "
United States
Karen
$116 nightly
The price is $130
Mar 16 - Mar 17
Total with taxes and fees
Hyatt Place Florence Downtown

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.2 out of 10, Wonderful, (1,234 reviews)
"Room was very nice "
United States
Andrew
$99 nightly
The price is $110
Mar 8 - Mar 9
Total with taxes and fees
Comfort Inn & Suites Florence Center Area

The Inn at the Crossroads

The Inn at the Crossroads
2.0 star property
Lake City
9.4 out of 10, Exceptional, (858 reviews)
"We always enjoy our stay at the Inn. Food at the Bistro never disappoints and the bartender is always friendly and remembers us from past visits. "
United States
Barbara
$165 nightly
The price is $185
Mar 24 - Mar 25
Total with taxes and fees
The Inn at the Crossroads

Quality Inn Mullins - Marion

Quality Inn Mullins - Marion
2.5 star property
Marion
7.6 out of 10, Good, (390 reviews)
"It was ok clean would stay there again. "
United States
jeff
$99 nightly
The price is $108
Mar 13 - Mar 14
Total with taxes and fees
Quality Inn Mullins - Marion

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
Florence
9.2 out of 10, Wonderful, (1,004 reviews)
"Clean rooms and nice breakfast. "
United States
Adam
$118 nightly
The price is $132
Mar 8 - Mar 9
Total with taxes and fees
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (961 reviews)
"Room clean, bed good, breakfast good choices, front desk excellent"
United States
mona
$135 nightly
The price is $151
Mar 29 - Mar 30
Total with taxes and fees
Staybridge Suites Florence - Civic Center by IHG

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2,249 reviews)
"Room was clean, staff friendly, and the includes breakfast was great "
United States
Samantha
$86 nightly
The price is $96
Mar 8 - Mar 9
Total with taxes and fees
Park Inn by Radisson Florence, SC

Hilton Garden Inn Florence

Hilton Garden Inn Florence
2.5 star property
Florence
8.6 out of 10, Excellent, (285 reviews)
"The hotel is very pet friendly. Close to stores and restaurants. Clean, friendly, for is great in the restaurant in the hotel as well. "
United States
Michelle
$114 nightly
The price is $128
Mar 15 - Mar 16
Total with taxes and fees
Hilton Garden Inn Florence

Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
Florence
9.0 out of 10, Wonderful, (857 reviews)
"Staff was very kind and conscious of our needs"
United States
Robert
$110 nightly
The price is $123
Apr 5 - Apr 6
Total with taxes and fees
Hampton Inn & Suites Florence Center

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2,580 reviews)
"I nice place to stay, very quiet, good breakfast, nice staff, spotless room. "
United States
Timothy
$70 nightly
The price is $79
Mar 10 - Mar 11
Total with taxes and fees
Howard Johnson by Wyndham Florence

Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.4 out of 10, Very Good, (1,004 reviews)
"We enjoyed our stay. Everything stood out Staff, Clean room and Amenities. "
United States
Marita
$101 nightly
The price is $113
Mar 15 - Mar 16
Total with taxes and fees
Tru by Hilton Florence I-95

Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center
2.5 star property
Florence
7.0 out of 10, Good, (1,007 reviews)
"Love this room dearly"
United States
Andre
$69 nightly
The price is $77
Mar 8 - Mar 9
Total with taxes and fees
Days Inn by Wyndham Florence Near Civic Center

Rodeway Inn Florence Downtown

Rodeway Inn Florence Downtown
2.0 star property
Florence
6.0 out of 10, (2 reviews)
"Good"
United States
Joshua
$50 nightly
The price is $56
Apr 4 - Apr 5
Total with taxes and fees
Rodeway Inn Florence Downtown

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
7.8 out of 10, Good, (1,671 reviews)
"Clean rooms, friendly staff, great breakfast "
United States
Donna
$104 nightly
The price is $117
Mar 15 - Mar 16
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Florence

Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG
2.5 star property
Latta
9.4 out of 10, Exceptional, (561 reviews)
"Front desk is amazing! Rooms are clean and quiet. "
United States
Kimberly
$118 nightly
The price is $129
Mar 11 - Mar 12
Total with taxes and fees
Holiday Inn Express & Suites Latta by IHG

Quality Inn & Suites Lake City

Quality Inn & Suites Lake City
2.5 star property
Lake City
7.0 out of 10, Good, (168 reviews)
"Good for the weekend. "
United States
Amber
$115 nightly
The price is $129
Mar 22 - Mar 23
Total with taxes and fees
Quality Inn & Suites Lake City

Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
Florence
8.8 out of 10, Excellent, (620 reviews)
"Special place. Great staff with an outstanding restaurant "
United States
John D
$130 nightly
The price is $146
Apr 5 - Apr 6
Total with taxes and fees
Hotel Florence, Tapestry Collection by Hilton

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
7.8 out of 10, Good, (1,275 reviews)
"Quiet clean and many options local for food etc Good for a night or two stay Bed was comfortable "
United States
Louis
$96 nightly
The price is $108
Mar 29 - Mar 30
Total with taxes and fees
Quality Inn & Suites Florence Civic Center

Residence Inn Marriott Florence

Residence Inn Marriott Florence
3.0 star property
Florence
8.8 out of 10, Excellent, (520 reviews)
"Clean room, great location, easy check-in & check-out, friendly service"
United States
Shaun
$107 nightly
The price is $120
Mar 15 - Mar 16
Total with taxes and fees
Residence Inn Marriott Florence

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.0 out of 10, Very Good, (51 reviews)
"Wonderful staff and very clean room and facilities , "
United States
catherine
$109 nightly
The price is $122
Apr 5 - Apr 6
Total with taxes and fees
Spark by Hilton Florence North I-95, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Effingham Hotel Reviews

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Frequently asked questions

What is the best area to stay in Effingham?
The best area to stay in Effingham is near the intersection of US-301 and I-95, as this offers the most convenient access to amenities and onward travel.

This area is primarily characterized by its array of hotels, restaurants, and gas stations, strategically located for travelers passing through or needing a stopover. You'll find most services concentrated along US-301, just off the I-95 exits. While not a tourist destination in itself, it provides all the necessary conveniences for a comfortable stay.

For solo travelers or couples on a road trip, this location is ideal. It offers quick access to the interstate, making it easy to continue your journey. The concentration of dining options, from casual eateries to sit-down restaurants, provides variety without requiring extensive travel.
When is the best time to go to Effingham?
The best time to visit Effingham, South Carolina, is during the spring (March to May) and fall (September to November) months.

These seasons offer pleasant weather with mild temperatures, ideal for enjoying outdoor activities without the intense heat and humidity of summer or the cooler, sometimes unpredictable, temperatures of winter. Spring brings blooming flora, while fall showcases colorful foliage, making for scenic drives and comfortable exploration of the local area.

For travelers who prefer warm weather and don't mind higher humidity, the summer months (June to August) are also an option. During this time, the days are long, allowing for extended outdoor enjoyment, though afternoon thunderstorms can occur.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Effingham.
How can I save on a Effingham hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Effingham hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Effingham hotel?
Prices for hotels in Effingham often vary, but you can find a great deal from $56 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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