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Our top choices for Effingham hotels

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
9.0 out of 10, Wonderful, (1,000 reviews)
"It was a beautiful room and breakfast was great. Staff was wonderful "
United States
Stephanie
$118 nightly
The price is $132
Mar 30 - Mar 31
Total with taxes and fees
Hyatt Place Florence Downtown

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,232 reviews)
"Clean room, good breakfast...very nice overnight stay."
United States
Gerry
$105 nightly
The price is $118
Apr 5 - Apr 6
Total with taxes and fees
Comfort Inn & Suites Florence Center Area

The Inn at the Crossroads

The Inn at the Crossroads
2.0 star property
Lake City
9.4 out of 10, Exceptional, (862 reviews)
"Very nice staff, peaceful location very clean up-to-date modern"
United States
Shayvan
$161 nightly
The price is $181
Mar 25 - Mar 26
Total with taxes and fees
The Inn at the Crossroads

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (970 reviews)
"Nice room and great breakfast "
United States
David
$135 nightly
The price is $151
Apr 5 - Apr 6
Total with taxes and fees
Staybridge Suites Florence - Civic Center by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
Florence
9.2 out of 10, Wonderful, (1,000 reviews)
"Awesome stay—fantastic staff"
United States
Stephanie
$127 nightly
The price is $142
Apr 5 - Apr 6
Total with taxes and fees
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Quality Inn Mullins - Marion

Quality Inn Mullins - Marion
2.5 star property
Marion
7.8 out of 10, Good, (393 reviews)
"It was ok clean would stay there again. "
United States
jeff
$98 nightly
The price is $107
Mar 28 - Mar 29
Total with taxes and fees
Quality Inn Mullins - Marion

Hilton Garden Inn Florence

Hilton Garden Inn Florence
2.5 star property
Florence
8.6 out of 10, Excellent, (291 reviews)
"Very nice stay. Very clean hotel"
United States
mark
$114 nightly
The price is $128
Mar 29 - Mar 30
Total with taxes and fees
Hilton Garden Inn Florence

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2,235 reviews)
"Staff was helpful and the room/bathroom were very nice."
United States
Diane
$86 nightly
The price is $96
Mar 29 - Mar 30
Total with taxes and fees
Park Inn by Radisson Florence, SC

Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
Florence
9.0 out of 10, Wonderful, (860 reviews)
"Parking convenient. Room clean and bed very comfortable. Would recommend and plan to stay again."
United States
MG
$110 nightly
The price is $123
Mar 29 - Mar 30
Total with taxes and fees
Hampton Inn & Suites Florence Center

Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center
2.5 star property
Florence
7.0 out of 10, Good, (1,000 reviews)
"Clean, very quiet , staff very friendly, safe place. "
United States
María
$60 nightly
The price is $68
Mar 24 - Mar 25
Total with taxes and fees
Days Inn by Wyndham Florence Near Civic Center

Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
Florence
8.8 out of 10, Excellent, (622 reviews)
"Nice room. Good breakfast. Interesting town"
United States
Noel
$130 nightly
The price is $146
Apr 5 - Apr 6
Total with taxes and fees
Hotel Florence, Tapestry Collection by Hilton

Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.4 out of 10, Very Good, (1,000 reviews)
"Everything was great...clean property and friendly staff! "
United States
Lasonia
$101 nightly
The price is $113
Mar 29 - Mar 30
Total with taxes and fees
Tru by Hilton Florence I-95

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2,574 reviews)
"The staff is awesome really nice hotel exciting the expectations "
United States
Victor
$67 nightly
The price is $75
Mar 29 - Mar 30
Total with taxes and fees
Howard Johnson by Wyndham Florence

Residence Inn Marriott Florence

Residence Inn Marriott Florence
3.0 star property
Florence
8.8 out of 10, Excellent, (525 reviews)
"A great place to stay to break up a long drive from Kissimmee to Washington DC"
United States
Frede
$114 nightly
The price is $128
Mar 23 - Mar 24
Total with taxes and fees
Residence Inn Marriott Florence

Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG
2.5 star property
Latta
9.6 out of 10, Exceptional, (566 reviews)
"Great visit to this site...convenient to food, gas, and the staff was so pleasant. Breakfast was very good and I would not hesitate to stay there again"
United States
Cheryl
$122 nightly
The price is $133
Apr 6 - Apr 7
Total with taxes and fees
Holiday Inn Express & Suites Latta by IHG

Rodeway Inn Florence Downtown

Rodeway Inn Florence Downtown
2.0 star property
Florence
4.8 out of 10, (3 reviews)
"Good"
United States
Joshua
$57 nightly
The price is $63
Apr 17 - Apr 18
Total with taxes and fees
Rodeway Inn Florence Downtown

Aloft Florence

Aloft Florence
3.0 star property
Florence
8.6 out of 10, Excellent, (295 reviews)
"Parking is great "
United States
cheto
$103 nightly
The price is $115
Mar 23 - Mar 24
Total with taxes and fees
Aloft Florence

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
7.8 out of 10, Good, (54 reviews)
"Wonderful staff and very clean room and facilities , "
United States
catherine
$109 nightly
The price is $122
Mar 25 - Mar 26
Total with taxes and fees
Spark by Hilton Florence North I-95, SC

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
8.0 out of 10, Very Good, (1,650 reviews)
"Clean rooms, friendly staff, great breakfast "
United States
Donna
$108 nightly
The price is $121
Mar 29 - Mar 30
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Florence

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
7.8 out of 10, Good, (1,268 reviews)
"Clean, quiet and safe location to spend the night. "
Canada
David
$93 nightly
The price is $104
Mar 23 - Mar 24
Total with taxes and fees
Quality Inn & Suites Florence Civic Center
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Top Effingham Hotel Reviews

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Frequently asked questions

What is the best area to stay in Effingham?
The best area to stay in Effingham is near the intersection of US-301 and I-95, as this offers the most convenient access to amenities and onward travel.

This area is primarily characterized by its array of hotels, restaurants, and gas stations, strategically located for travelers passing through or needing a stopover. You'll find most services concentrated along US-301, just off the I-95 exits. While not a tourist destination in itself, it provides all the necessary conveniences for a comfortable stay.

For solo travelers or couples on a road trip, this location is ideal. It offers quick access to the interstate, making it easy to continue your journey. The concentration of dining options, from casual eateries to sit-down restaurants, provides variety without requiring extensive travel.
When is the best time to go to Effingham?
The best time to visit Effingham, South Carolina, is during the spring (March to May) and fall (September to November) months.

These seasons offer pleasant weather with mild temperatures, ideal for enjoying outdoor activities without the intense heat and humidity of summer or the cooler, sometimes unpredictable, temperatures of winter. Spring brings blooming flora, while fall showcases colorful foliage, making for scenic drives and comfortable exploration of the local area.

For travelers who prefer warm weather and don't mind higher humidity, the summer months (June to August) are also an option. During this time, the days are long, allowing for extended outdoor enjoyment, though afternoon thunderstorms can occur.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Effingham.
How can I save on a Effingham hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Effingham hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Effingham hotel?
Prices for hotels in Effingham often vary, but you can find a great deal from $63 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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