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Sep 26 - Sep 27
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Sep 27 - Sep 28
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Oct 2 - Oct 4
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Oct 9 - Oct 11

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Our top choices for Effingham hotels

A spacious lobby with a checkered floor, a reception desk, and a chandelier.
A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.
A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.
A two-story building with a brick facade, a flat roof, and a covered entrance area.

1. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
Florence
United States
HOMERO
$65 nightly
$72 total
Sep 27 - Sep 28
Total with taxes and fees
Howard Johnson by Wyndham Florence
A hotel lobby with a reception desk, seating area, and a television screen.
A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.
A hotel room with a bed, a sofa, an ottoman, and a lamp.
A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.

2. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
Florence
United States
Mila
$101 nightly
$113 total
Oct 18 - Oct 19
Total with taxes and fees
Comfort Inn & Suites Florence Center Area
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.
A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.
A modern hotel with a 'Park Inn by Radisson' sign, featuring a covered entrance, multiple windows, and a parking lot.

3. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
Florence
United States
Windia
$89 nightly
$100 total
Oct 4 - Oct 5
Total with taxes and fees
Park Inn by Radisson Florence, SC
A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
A modern lounge area with brick walls, large windows, and contemporary furniture.
A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.
A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.

4. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
Florence
United States
Shanti
$110 nightly
$123 total
Oct 5 - Oct 6
Total with taxes and fees
Hyatt Place Florence Downtown
A hotel room with a desk, chair, bed, and a yellow sofa.
A hotel dining area with wooden tables and chairs, a fireplace, and a television.
A hotel with a green roof, a sign reading 'Quality Inn & Suites by Choice Hotels,' and a landscaped front yard with small trees and shrubs.
A swimming pool with lounge chairs and a building with balconies.

5. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
Florence
Canada
Noémie
$95 nightly
$107 total
Oct 3 - Oct 4
Total with taxes and fees
Quality Inn & Suites Florence Civic Center
An outdoor patio area with tables and chairs, a brick wall, and a glass door leading to the interior.
A spacious lobby with a grand staircase, plush seating, and a modern kitchen area.
A spacious bar area with a wooden floor, multiple bar stools, and a variety of bottles on shelves.
A spacious living room with hardwood flooring, a staircase, and a large window.

6. The Inn at the Crossroads

The Inn at the Crossroads
Lake City
United States
Paige
$91 nightly
$102 total
Oct 27 - Oct 28
Total with taxes and fees
The Inn at the Crossroads
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.
An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.
A hotel room with two beds, a desk with a chair, a television, and a window with curtains.
A hotel with a modern design, featuring a prominent sign for the 'Country Inn & Suites by Radisson.'

7. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
Florence
United States
Tienia
$85 nightly
$95 total
Oct 18 - Oct 19
Total with taxes and fees
Spark by Hilton Florence North I-95, SC
A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.
A spacious lobby with a reception desk, a large window display, and a 'market' sign on the wall.
A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.

8. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
Florence
United States
John
$102 nightly
$114 total
Oct 18 - Oct 19
Total with taxes and fees
SpringHill Suites by Marriott Florence
A restaurant with brick walls, framed awards, and a bar area.
A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.
A spacious kitchen with a dining area, a living room with a fireplace, and a cozy seating arrangement.
An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.

9. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
Florence
United States
Ankh
$127 nightly
$142 total
Oct 22 - Oct 23
Total with taxes and fees
Hotel Florence, Tapestry Collection by Hilton
A Courtyard by Marriott hotel with a covered entrance, multiple floors, and a parking lot.
A hotel room with two beds, a desk, a chair, and a TV.
A hotel room with a flat-screen TV, a desk with a chair, a sofa, a small table, and a balcony with outdoor seating.
A modern bar area with a counter, stools, and tables.

10. Courtyard by Marriott Florence

Courtyard by Marriott Florence
Florence
United States
George
$102 nightly
$114 total
Oct 4 - Oct 5
Total with taxes and fees
Courtyard by Marriott Florence
A hotel entrance with a stone facade, glass doors, and a number '501' above.
A corner market with shelves stocked with snacks and beverages, and two large refrigerators.
A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.
An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.

11. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
Florence
United States
Felecia
$127 nightly
$142 total
Oct 1 - Oct 2
Total with taxes and fees
Fairfield Inn & Suites by Marriott Florence I-20
A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.
A modern office space with two desks, chairs, a printer, and a colorful abstract painting on the wall.
A coffee station with two coffee machines and a display of coffee pods and cups.
A conference room with a long table, chairs, a coffee station, and a clock on the wall.

12. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Florence
United States
Leigh
$126 nightly
$141 total
Oct 26 - Oct 27
Total with taxes and fees
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A building with two red doors, one labeled 'Office' and the other '101'. There is a welcome sign and a mailbox on the wall.
A room with a sofa, a small table, a chair, a lamp, and a door.
A compact kitchen with a dining area, a TV, and a small table.
A house with a stone-paved entrance, a bench, and two red doors labeled "OFFICE" and "PRIVATE."

13. Affordable Suites Florence

Affordable Suites Florence
Florence
United States
Cheyenne
$84 nightly
$94 total
Oct 7 - Oct 8
Total with taxes and fees
Affordable Suites Florence
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.
A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.
A modern kitchen with a coffee station, a dining area with a table and chairs, and a living area with a sofa and a coffee table.
A modern lounge area with a sofa, armchairs, and small tables.

14. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
Florence
United Kingdom
William
$118 nightly
$132 total
Sep 27 - Sep 28
Total with taxes and fees
TownePlace Suites by Marriott Florence
A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.
A modern breakfast area with a buffet setup, including a microwave, coffee maker, and various food items.
A La Quinta Inn & Suites hotel with a modern facade, a well-lit entrance, and a landscaped garden area.
A hotel room with a bed, a sofa, a desk, and a TV.

15. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
Florence
United States
Heather
$89 nightly
$100 total
Sep 29 - Sep 30
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Florence
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.
A hotel room with two beds, a desk, a TV, and a window with patterned curtains.
A hotel lobby with a reception desk, seating area, and a welcome mat.

16. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
Florence
United States
Bill
$110 nightly
$123 total
Oct 25 - Oct 26
Total with taxes and fees
Hampton Inn & Suites Florence Center
A hotel room with two beds, a wooden headboard, a nightstand, and three sunset paintings on the wall.
A lobby with a reception desk, seating area, and artwork on the walls.
A Days Inn hotel with a modern design, featuring a parking lot and well-maintained landscaping.
A modern hotel room with a large bed, two armchairs, a desk with a computer, and a decorative wall.

17. Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center
Florence
United States
Jefferson
$69 nightly
$77 total
Sep 27 - Sep 28
Total with taxes and fees
Days Inn by Wyndham Florence Near Civic Center
A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.
A hotel room with a bed, a desk, a TV, a refrigerator, and a painting on the wall.
A hotel room with a sofa, a dining table, a coffee maker, a TV, and artwork on the wall.
A conference room with round tables, chairs, and a carpeted floor.

18. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
Florence
United States
Tishia
$143 nightly
$160 total
Oct 4 - Oct 5
Total with taxes and fees
Staybridge Suites Florence - Civic Center by IHG
A spacious room with a large window, a kitchenette, and two chairs.
A hotel room with a large bed, a nightstand, a wall-mounted light, a painting, and a separate bathroom with a bathtub.
A reception area with a reception desk, a large window, and a door.
A modern office entrance with a glass door, a 'PULL' sign, a reception desk, and a view of the parking area.

19. Florence Inn and Suites

Florence Inn and Suites
Florence
United States
Anthony
$41 nightly
$46 total
Sep 29 - Sep 30
Total with taxes and fees
Florence Inn and Suites
A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.
A buffet with various food items, including omelets and baked goods, served in metal containers.
A hotel reception desk with two computer monitors, a desk lamp, and framed artwork on the wall.

20. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
Florence
United States
Christopher
$132 nightly
$148 total
Oct 25 - Oct 26
Total with taxes and fees
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
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Top Effingham Hotel Reviews

The Inn at the Crossroads

The Inn at the Crossroads

8/10 Good
"Everything was great. No problems"
Scarline 1-night trip
Posted 2 hours ago
The Inn at the Crossroads
SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence

8/10 Good
"Breakfast was very good, friendly and helpful staff. A bit rundown in some aspects and the pull out trundle mattress was like laying on steel springs. Otherwise was a good stay overall."
Daniel 1-night trip
Posted 3 hours ago
SpringHill Suites by Marriott Florence
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

10/10 Excellent
"The front desk person was amazing!"
Debbie 1-night trip
Posted 19 hours ago
Park Inn by Radisson Florence, SC
Comfort Suites Florence I-95

Comfort Suites Florence I-95

10/10 Excellent
"Parfait"
Meyranie 1-night trip
Posted 23 hours ago
Comfort Suites Florence I-95
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

10/10 Excellent
"Rooms are clean, beds are comfortable, the shower is great!! Staff are great also!"
Dave 1-night trip
Posted 23 hours ago
Howard Johnson by Wyndham Florence
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

10/10 Excellent
"Lately I have been disappointed in my motels when I travel. I have to say this one was a great experience. Very clean and comfortable."
Robert 1-night trip
Posted 2 days ago
La Quinta Inn & Suites by Wyndham Florence
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

10/10 Excellent
"Stayed for a wedding nearby. It was perfect! The breakfast was also a huge plus with the fresh ground coffee."
Collin 2-night trip
Posted 2 days ago
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

10/10 Excellent
"Great stay! Would definitely stay again!"
Vincent 1-night trip
Posted 3 days ago
Quality Inn & Suites Florence Civic Center
TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

10/10 Excellent
"Many special touches were evident from the entrance to everything in my room, through breakfast and departure. The desk attendant recommended a wonderful Mexican restaurant only 3 minutes away. Absolutely amazing service!"
Ron 1-night trip
Posted 4 days ago
TownePlace Suites by Marriott Florence

More cheap stays in Effingham

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC
$65 nightly
$72 total
Sep 27 - Sep 28
Total with taxes and fees
Howard Johnson by Wyndham Florence
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

140 Dunbarton Dr Florence SC
$69 nightly
$77 total
Sep 27 - Sep 28
Total with taxes and fees
Days Inn by Wyndham Florence Near Civic Center
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

1729 Mandeville Road Florence SC
$89 nightly
$100 total
Oct 4 - Oct 5
Total with taxes and fees
9/10 Wonderful! (2,455 reviews)
Park Inn by Radisson Florence, SC
The Inn at the Crossroads

The Inn at the Crossroads

128 West Main Street Lake City SC
$91 nightly
$102 total
Oct 27 - Oct 28
Total with taxes and fees
9.4/10 Exceptional! (983 reviews)
The Inn at the Crossroads
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

150 Dunbarton Dr Florence SC
$95 nightly
$107 total
Oct 3 - Oct 4
Total with taxes and fees
Quality Inn & Suites Florence Civic Center
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

527 Woody Jones Blvd Florence SC
$101 nightly
$113 total
Oct 18 - Oct 19
Total with taxes and fees
Comfort Inn & Suites Florence Center Area

Hotels in Effingham with star-rating

Frequently asked questions

What is the best area to stay in Effingham?
The best area to stay in Effingham is near the intersection of US-301 and I-95, as this offers the most convenient access to amenities and onward travel.This area is primarily characterized by its array of hotels, restaurants, and gas stations, strategically located for travelers passing through or needing a stopover. You'll find most services concentrated along US-301, just off the I-95 exits. While not a tourist destination in itself, it provides all the necessary conveniences for a comfortable stay.For solo travelers or couples on a road trip, this location is ideal. It offers quick access to the interstate, making it easy to continue your journey. The concentration of dining options, from casual eateries to sit-down restaurants, provides variety without requiring extensive travel.
When is the best time to go to Effingham?
The best time to visit Effingham, South Carolina, is during the spring (March to May) and fall (September to November) months.These seasons offer pleasant weather with mild temperatures, ideal for enjoying outdoor activities without the intense heat and humidity of summer or the cooler, sometimes unpredictable, temperatures of winter. Spring brings blooming flora, while fall showcases colorful foliage, making for scenic drives and comfortable exploration of the local area.For travelers who prefer warm weather and don't mind higher humidity, the summer months (June to August) are also an option. During this time, the days are long, allowing for extended outdoor enjoyment, though afternoon thunderstorms can occur.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Effingham.
How much is the nightly rate at a Effingham hotel?
Prices for hotels in Effingham often vary, but you can find a great deal from $46 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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