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Our top choices for Effingham hotels

Quality Inn Mullins - Marion

Quality Inn Mullins - Marion
2.5 star property
Marion
7.8 out of 10, Good, (398 reviews)
"It was ok clean would stay there again. "
United States
jeff
$98 nightly
The price is $107
May 21 - May 22
Total with taxes and fees
Quality Inn Mullins - Marion

Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG
2.5 star property
Latta
9.4 out of 10, Exceptional, (583 reviews)
"Great stay"
United States
Nicole
$110 nightly
The price is $120
May 17 - May 18
Total with taxes and fees
Holiday Inn Express & Suites Latta by IHG

Best Western Executive Inn

Best Western Executive Inn
2.5 star property
Latta
8.2 out of 10, Very Good, (987 reviews)
"I had a wonderful stay at the hotel, where the staff was incredibly friendly and attentive. The clean and comfortable rooms, along with the convenient location, made my experience truly enjoyable!"
United States
Taras
$106 nightly
The price is $116
May 5 - May 6
Total with taxes and fees
Best Western Executive Inn

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2,655 reviews)
"Great stay"
United States
Priscila
$66 nightly
The price is $74
Apr 29 - Apr 30
Total with taxes and fees
Howard Johnson by Wyndham Florence

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,269 reviews)
"I love this place I would stay again "
United States
Shunicee
$90 nightly
The price is $101
May 24 - May 25
Total with taxes and fees
Comfort Inn & Suites Florence Center Area

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.0 out of 10, Very Good, (85 reviews)
"Clean rooms. Helpful staff good location. It will be better if they offer better options in breakfast."
United States
TORAL
$93 nightly
The price is $104
May 5 - May 6
Total with taxes and fees
Spark by Hilton Florence North I-95, SC

Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
Florence
8.4 out of 10, Very Good, (1,003 reviews)
"The breakfast was great and the rooms were super comfortable "
United States
Jessica
$99 nightly
The price is $110
May 26 - May 27
Total with taxes and fees
Comfort Suites Florence I-95

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (899 reviews)
"Great staff. Great place to stay!"
United States
Debra
$103 nightly
The price is $116
May 10 - May 11
Total with taxes and fees
Hampton Inn & Suites Florence-North-I-95

Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center
2.5 star property
Florence
7.0 out of 10, Good, (1,010 reviews)
"Location"
United States
Lester
$66 nightly
The price is $74
Apr 29 - Apr 30
Total with taxes and fees
Days Inn by Wyndham Florence Near Civic Center

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2,266 reviews)
"Great stay!"
United States
Lisa
$76 nightly
The price is $85
May 25 - May 26
Total with taxes and fees
Park Inn by Radisson Florence, SC

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
8.6 out of 10, Excellent, (111 reviews)
"Great place to stop and rest "
United States
Juan Miguel
$95 nightly
The price is $106
May 10 - May 11
Total with taxes and fees
Quality Inn & Suites Florence Civic Center

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1,003 reviews)
"One night stay"
United States
Dalet
$127 nightly
The price is $142
May 3 - May 4
Total with taxes and fees
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Best Western Inn

Best Western Inn
2.5 star property
Florence
7.8 out of 10, Good, (1,001 reviews)
"For a roadside hotel it felt clean and pleasant. "
United States
Marianna
$99 nightly
The price is $111
Apr 29 - Apr 30
Total with taxes and fees
Best Western Inn

Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
Florence
8.8 out of 10, Excellent, (631 reviews)
"Nice room. Good breakfast. Interesting town"
United States
Noel
$130 nightly
The price is $146
May 7 - May 8
Total with taxes and fees
Hotel Florence, Tapestry Collection by Hilton

Aloft Florence

Aloft Florence
3.0 star property
Florence
8.6 out of 10, Excellent, (317 reviews)
"Room was very clean smaller but clean. "
United States
Lashader
$111 nightly
The price is $124
May 25 - May 26
Total with taxes and fees
Aloft Florence

Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.4 out of 10, Very Good, (1,003 reviews)
"It was clean and breakfast was good "
United States
Samina
$101 nightly
The price is $113
May 5 - May 6
Total with taxes and fees
Tru by Hilton Florence I-95

Super 8 by Wyndham Florence

Super 8 by Wyndham Florence
2.0 star property
Florence
7.0 out of 10, Good, (1,002 reviews)
"Clean room and great staff."
United States
Sameer
$57 nightly
The price is $64
Apr 29 - Apr 30
Total with taxes and fees
Super 8 by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
7.8 out of 10, Good, (1,603 reviews)
"Very nice place to spend the night."
United States
Sharon
$97 nightly
The price is $109
May 3 - May 4
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Florence

Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North
2.0 star property
Florence
6.6 out of 10, (1,007 reviews)
"Very nice rooms."
United States
Robert
$54 nightly
The price is $60
Apr 29 - Apr 30
Total with taxes and fees
Days Inn by Wyndham Florence/I-95 North

Courtyard by Marriott Florence

Courtyard by Marriott Florence
3.0 star property
Florence
7.8 out of 10, Good, (729 reviews)
"Very nice stay, quiet & clean. Staff was very nice as well. "
United States
Eric
$97 nightly
The price is $109
May 7 - May 8
Total with taxes and fees
Courtyard by Marriott Florence
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Top Effingham Hotel Reviews

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Frequently asked questions

What is the best area to stay in Effingham?
The best area to stay in Effingham is near the intersection of US-301 and I-95, as this offers the most convenient access to amenities and onward travel.

This area is primarily characterized by its array of hotels, restaurants, and gas stations, strategically located for travelers passing through or needing a stopover. You'll find most services concentrated along US-301, just off the I-95 exits. While not a tourist destination in itself, it provides all the necessary conveniences for a comfortable stay.

For solo travelers or couples on a road trip, this location is ideal. It offers quick access to the interstate, making it easy to continue your journey. The concentration of dining options, from casual eateries to sit-down restaurants, provides variety without requiring extensive travel.
When is the best time to go to Effingham?
The best time to visit Effingham, South Carolina, is during the spring (March to May) and fall (September to November) months.

These seasons offer pleasant weather with mild temperatures, ideal for enjoying outdoor activities without the intense heat and humidity of summer or the cooler, sometimes unpredictable, temperatures of winter. Spring brings blooming flora, while fall showcases colorful foliage, making for scenic drives and comfortable exploration of the local area.

For travelers who prefer warm weather and don't mind higher humidity, the summer months (June to August) are also an option. During this time, the days are long, allowing for extended outdoor enjoyment, though afternoon thunderstorms can occur.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Effingham.
How can I save on a Effingham hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Effingham hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Effingham hotel?
Prices for hotels in Effingham often vary, but you can find a great deal from $60 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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