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Sep 13 - Sep 14
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Sep 14 - Sep 15
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Sep 18 - Sep 20
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Our top choices for Effingham hotels

A spacious lobby with a checkered floor, a reception desk, and a chandelier.
A two-story building with a brick facade, a flat roof, and a covered entrance area.
A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.
A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.

1. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
Florence
United States
HOMERO
$64 nightly
$71 total
Oct 13 - Oct 14
Total with taxes and fees
Howard Johnson by Wyndham Florence
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.
A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.
A modern hotel with a 'Park Inn by Radisson' sign, featuring a covered entrance, multiple windows, and a parking lot.

2. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
Florence
United States
frank
$89 nightly
$100 total
Sep 20 - Sep 21
Total with taxes and fees
Park Inn by Radisson Florence, SC
A hotel lobby with a reception desk, seating area, and a television screen.
A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.
A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.
A hotel room with a bed, a sofa, an ottoman, and a lamp.

3. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
Florence
United States
Mike
$105 nightly
$118 total
Oct 4 - Oct 5
Total with taxes and fees
Comfort Inn & Suites Florence Center Area
A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.
A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.
A modern lounge area with brick walls, large windows, and contemporary furniture.

4. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
Florence
United States
Evan
$110 nightly
$123 total
Oct 1 - Oct 2
Total with taxes and fees
Hyatt Place Florence Downtown
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.
An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.
A hotel room with two beds, a desk with a chair, a television, and a window with curtains.
A modern cafeteria with long wooden tables, green chairs, and yellow accents.

5. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
Florence
United States
Michelle
$85 nightly
$95 total
Oct 4 - Oct 5
Total with taxes and fees
Spark by Hilton Florence North I-95, SC
A swimming pool with lounge chairs and a building with balconies.
A hotel dining area with wooden tables and chairs, a fireplace, and a television.
A hotel with a green roof, a sign reading 'Quality Inn & Suites by Choice Hotels,' and a landscaped front yard with small trees and shrubs.
A swimming pool with a metal ladder, lounge chairs, and a building with balconies.

6. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
Florence
Canada
Noémie
$89 nightly
$100 total
Sep 20 - Sep 21
Total with taxes and fees
Quality Inn & Suites Florence Civic Center
An outdoor patio area with tables and chairs, a brick wall, and a glass door leading to the interior.
A spacious dining area with multiple tables and chairs, wooden flooring, and a modern chandelier.
A spacious lobby with a grand staircase, plush seating, and a modern kitchen area.
A spacious living room with hardwood flooring, a staircase, and a large window.

7. The Inn at the Crossroads

The Inn at the Crossroads
Lake City
United States
Paige
$91 nightly
$102 total
Oct 14 - Oct 15
Total with taxes and fees
The Inn at the Crossroads
A hotel entrance with a stone facade, glass doors, and a number '501' above.
A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.
A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.
An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.

8. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
Florence
United States
Felecia
$127 nightly
$142 total
Sep 17 - Sep 18
Total with taxes and fees
Fairfield Inn & Suites by Marriott Florence I-20
A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.
A hotel room with a bed, a sofa, a desk, and a TV.
A La Quinta Inn & Suites hotel with a modern facade, a well-lit entrance, and a landscaped garden area.
A hotel room with a bed, sofa, TV, and a desk.

9. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
Florence
United States
Heather
$86 nightly
$96 total
Sep 20 - Sep 21
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Florence
A building with two red doors, one labeled 'Office' and the other '101'. There is a welcome sign and a mailbox on the wall.
A compact kitchen with a dining area, a TV, and a small table.
A compact living space with a dining area, kitchenette, and seating area.
A house with a stone-paved entrance, a bench, and two red doors labeled "OFFICE" and "PRIVATE."

10. Affordable Suites Florence

Affordable Suites Florence
Florence
United States
Cheyenne
$77 nightly
$86 total
Sep 14 - Sep 15
Total with taxes and fees
Affordable Suites Florence
A restaurant with brick walls, framed awards, and a bar area.
A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.
An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.
A bar area with a curved counter, multiple stools, and a brick wall backdrop.

11. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
Florence
United States
Ankh
$139 nightly
$155 total
Sep 20 - Sep 21
Total with taxes and fees
Hotel Florence, Tapestry Collection by Hilton
A Courtyard by Marriott hotel with a covered entrance, multiple floors, and a parking lot.
An indoor swimming pool with clear water, surrounded by tiled walls and a wooden floor. There are chairs and a table near the pool, and large windows allow natural light to enter.
A hotel room with two beds, a desk, a chair, and a TV.
A modern bar area with a counter, stools, and tables.

12. Courtyard by Marriott Florence

Courtyard by Marriott Florence
Florence
United States
George
$102 nightly
$114 total
Sep 22 - Sep 23
Total with taxes and fees
Courtyard by Marriott Florence
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.
A modern kitchen with a coffee station, a dining area with a table and chairs, and a living area with a sofa and a coffee table.
A self-service beverage station with refrigerated and non-refrigerated drink options, snack shelves, and a sign indicating the location.
A modern lounge area with a sofa, armchairs, and small tables.

13. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
Florence
United Kingdom
William
$118 nightly
$132 total
Sep 14 - Sep 15
Total with taxes and fees
TownePlace Suites by Marriott Florence
A spacious room with a large window, a coffee machine, two chairs, and a potted plant.
A hotel room with a large bed, a nightstand, a wall-mounted light, a painting, and a separate bathroom with a bathtub.
A modern office entrance with a glass door, a pull handle, and a "PULL" sign.
A reception area with a reception desk, a large window, and a door.

14. Florence Inn and Suites

Florence Inn and Suites
Florence
United States
Anthony
$47 nightly
$53 total
Sep 21 - Sep 22
Total with taxes and fees
Florence Inn and Suites
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
A lobby with a fireplace, seating area, and a television.
A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.
A hotel lobby with a reception desk, seating area, and a welcome mat.

15. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
Florence
United States
Jennifer
$111 nightly
$124 total
Sep 20 - Sep 21
Total with taxes and fees
Hampton Inn & Suites Florence Center
A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.
A large, two-story building with a central entrance flanked by columns, labeled "DIR FRANK B. LEE NURSING BUILDING."
A swimming pool with lounge chairs and a view of the outdoors.

16. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
Florence
United States
Christopher
$135 nightly
$151 total
Oct 12 - Oct 13
Total with taxes and fees
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.
A hotel entrance with a covered walkway, a brick pathway, and a well-maintained garden.
A hotel room with a sofa, a dining table, a coffee maker, a TV, and artwork on the wall.
A swimming pool area with lounge chairs and umbrellas, surrounded by a white building with large windows.

17. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
Florence
United States
Frederick
$135 nightly
$151 total
Sep 20 - Sep 21
Total with taxes and fees
Staybridge Suites Florence - Civic Center by IHG
A hotel room with two beds, a wooden headboard, a nightstand, and three sunset paintings on the wall.
A modern kitchen with a central island, a dining area with chairs, a large window with a view of palm trees, and a flat-screen TV mounted on the wall.
A modern hotel room with a large bed, two armchairs, a desk with a computer, and a decorative wall.
A lobby with a reception desk, seating area, and artwork on the walls.

18. Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center
Florence
United States
BRANDY
$64 nightly
$72 total
Sep 28 - Sep 29
Total with taxes and fees
Days Inn by Wyndham Florence Near Civic Center
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.
A Hampton Inn & Suites hotel with a well-lit entrance, multiple floors, and a parking area.
An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.
A corridor with shelves stocked with snacks and a frozen food display.

19. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
Florence
United States
Michelle
$118 nightly
$132 total
Sep 20 - Sep 21
Total with taxes and fees
Hampton Inn & Suites Florence-North-I-95
A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.
A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.
A spacious lobby with a reception desk, a large window display, and a 'market' sign on the wall.

20. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
Florence
United States
Florence
$109 nightly
$122 total
Sep 20 - Sep 21
Total with taxes and fees
SpringHill Suites by Marriott Florence
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Top Effingham Hotel Reviews

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG

10/10 Excellent
"Let me start with staff they were very friendly, helpful, and very welcoming.. The room was very clean when I come back to Florence S.C. to visit with my sister and her family I will definitely book again."
Victoria 2-night trip
Posted 1 hour ago
Staybridge Suites Florence - Civic Center by IHG
The Inn at the Crossroads

The Inn at the Crossroads

10/10 Excellent
"Housekeeping was very respectful and pleasant. Some hotels the interactions with housekeeping makes you don't want them in your room even while you're there. Not The Inn at Crossroads. You will love the hospitality through out the whole hotel."
Bernard 1-night trip
Posted 5 hours ago
The Inn at the Crossroads
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

10/10 Excellent
"The room was clean and comfortable. The breakfast was hot and plentiful. We would stay here again."
Karen 1-night trip
Posted 17 hours ago
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Super 8 by Wyndham Florence

Super 8 by Wyndham Florence

8/10 Good
"Clean, good value, breakfast needed some hot food, coffee was weak & no coffee taste. Very bad. Air conditioner was nice and cool."
Agnes 1-night trip
Posted 19 hours ago
Super 8 by Wyndham Florence
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

10/10 Excellent
"Second time we’ve stopped at this hotel overnight and both times was a pleasant experience. The hotel is clean and our bedroom was very comfortable. We didn’t have any issues during our visits. If I had to mention something less favorable, it would be the room carpet in a pet friendly hotel. But that’s not a big issue for us. The staff here are wonderful, had a great conversation with the morning breakfast crew during our first visit. You can really feel the southern hospitality. We will be back when we’re in the area again."
Erwin 1-night trip
Posted 23 hours ago
Comfort Inn & Suites Florence Center Area
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

10/10 Excellent
"Good value for quick stop on Florence, SC"
Edward 1-night trip
Posted 3 days ago
Spark by Hilton Florence North I-95, SC
SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence

10/10 Excellent
"All very good"
Bonnie 1-night trip
Posted 8 days ago
SpringHill Suites by Marriott Florence

More cheap stays in Effingham

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC
$64 nightly
$71 total
Oct 13 - Oct 14
Total with taxes and fees
Howard Johnson by Wyndham Florence
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

150 Dunbarton Dr Florence SC
$89 nightly
$100 total
Sep 20 - Sep 21
Total with taxes and fees
Quality Inn & Suites Florence Civic Center
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

1729 Mandeville Road Florence SC
$89 nightly
$100 total
Sep 20 - Sep 21
Total with taxes and fees
Park Inn by Radisson Florence, SC
The Inn at the Crossroads

The Inn at the Crossroads

128 West Main Street Lake City SC
$91 nightly
$102 total
Oct 14 - Oct 15
Total with taxes and fees
9.4/10 Exceptional! (968 reviews)
The Inn at the Crossroads
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

527 Woody Jones Blvd Florence SC
$105 nightly
$118 total
Oct 4 - Oct 5
Total with taxes and fees
9/10 Wonderful! (1,361 reviews)
Comfort Inn & Suites Florence Center Area
Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

3000 W Radio Dr Florence SC
$111 nightly
$124 total
Sep 20 - Sep 21
Total with taxes and fees
Hampton Inn & Suites Florence Center

Hotels in Effingham with star-rating

Frequently asked questions

What is the best area to stay in Effingham?
The best area to stay in Effingham is near the intersection of US-301 and I-95, as this offers the most convenient access to amenities and onward travel.This area is primarily characterized by its array of hotels, restaurants, and gas stations, strategically located for travelers passing through or needing a stopover. You'll find most services concentrated along US-301, just off the I-95 exits. While not a tourist destination in itself, it provides all the necessary conveniences for a comfortable stay.For solo travelers or couples on a road trip, this location is ideal. It offers quick access to the interstate, making it easy to continue your journey. The concentration of dining options, from casual eateries to sit-down restaurants, provides variety without requiring extensive travel.
When is the best time to go to Effingham?
The best time to visit Effingham, South Carolina, is during the spring (March to May) and fall (September to November) months.These seasons offer pleasant weather with mild temperatures, ideal for enjoying outdoor activities without the intense heat and humidity of summer or the cooler, sometimes unpredictable, temperatures of winter. Spring brings blooming flora, while fall showcases colorful foliage, making for scenic drives and comfortable exploration of the local area.For travelers who prefer warm weather and don't mind higher humidity, the summer months (June to August) are also an option. During this time, the days are long, allowing for extended outdoor enjoyment, though afternoon thunderstorms can occur.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Effingham.
How much is the nightly rate at a Effingham hotel?
Prices for hotels in Effingham often vary, but you can find a great deal from $71 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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