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Find hotels in Effingham, SC from $72

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Oct 21 - Oct 22
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Oct 22 - Oct 23
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Oct 23 - Oct 25
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Our top choices for Effingham hotels

A spacious lobby with a checkered floor, a reception desk, and a chandelier.
A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.
A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.
A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.

1. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
Florence
United States
Alanda
$65 nightly
$72 total
Oct 22 - Oct 23
Total with taxes and fees
Howard Johnson by Wyndham Florence
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.
A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.
A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.

2. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
Florence
United States
Juan
$90 nightly
$101 total
Oct 25 - Oct 26
Total with taxes and fees
Park Inn by Radisson Florence, SC
A hotel lobby with a reception desk, seating area, and a television screen.
A hotel room with a bed, a sofa, an ottoman, and a lamp.
A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.
A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.

3. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
Florence
United States
Mila
$101 nightly
$113 total
Nov 11 - Nov 12
Total with taxes and fees
Comfort Inn & Suites Florence Center Area
A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.
A modern lounge area with brick walls, large windows, and contemporary furniture.
A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.

4. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
Florence
United States
JEFFREY
$100 nightly
$112 total
Nov 3 - Nov 4
Total with taxes and fees
Hyatt Place Florence Downtown
An outdoor patio area with tables and chairs, a brick wall, and a glass door leading to the interior.
A spacious dining area with multiple tables and chairs, wooden flooring, and a modern chandelier.
A spacious bar area with a wooden floor, multiple bar stools, and a variety of bottles on shelves.
A spacious lobby with a grand staircase, plush seating, and a modern kitchen area.

5. The Inn at the Crossroads

The Inn at the Crossroads
Lake City
United States
Paige
$126 nightly
$142 total
Nov 19 - Nov 20
Total with taxes and fees
The Inn at the Crossroads
A hotel room with a desk, chair, bed, and a yellow sofa.
A hotel with a green roof, a sign reading 'Quality Inn & Suites by Choice Hotels,' and a landscaped front yard with small trees and shrubs.
A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.
A hotel dining area with wooden tables and chairs, a fireplace, and a television.

6. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
Florence
United States
Sharhonda
$89 nightly
$100 total
Oct 27 - Oct 28
Total with taxes and fees
Quality Inn & Suites Florence Civic Center
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.
A hotel with a modern design, featuring a prominent sign for the 'Country Inn & Suites by Radisson.'
An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.
A modern cafeteria with long wooden tables, green chairs, and yellow accents.

7. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
Florence
United States
Tienia
$100 nightly
$112 total
Oct 27 - Oct 28
Total with taxes and fees
Spark by Hilton Florence North I-95, SC
A Courtyard by Marriott hotel with a covered entrance, multiple floors, and a parking lot.
A hotel room with a flat-screen TV, a desk with a chair, a sofa, a small table, and a balcony with outdoor seating.
An indoor swimming pool with clear water, surrounded by tiled walls and a wooden floor. There are chairs and a table near the pool, and large windows allow natural light to enter.
A hotel room with two beds, a desk, a chair, and a TV.

8. Courtyard by Marriott Florence

Courtyard by Marriott Florence
Florence
United States
Willie
$111 nightly
$124 total
Oct 28 - Oct 29
Total with taxes and fees
Courtyard by Marriott Florence
A restaurant with brick walls, framed awards, and a bar area.
A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.
An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.
A spacious kitchen with a dining area, a living room with a fireplace, and a cozy seating arrangement.

9. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
Florence
United States
Ankh
$139 nightly
$155 total
Oct 30 - Oct 31
Total with taxes and fees
Hotel Florence, Tapestry Collection by Hilton
A hotel entrance with a stone facade, glass doors, and a number '501' above.
A corner market with shelves stocked with snacks and beverages, and two large refrigerators.
A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.
A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.

10. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
Florence
United States
Alma
$118 nightly
$132 total
Oct 25 - Oct 26
Total with taxes and fees
Fairfield Inn & Suites by Marriott Florence I-20
A multi-story hotel with a prominent entrance and signage for Springhill Suites by Marriott.
A spacious lobby with a reception desk, a large window display, and a 'market' sign on the wall.
A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.
A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.

11. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
Florence
United States
John
$107 nightly
$119 total
Oct 26 - Oct 27
Total with taxes and fees
SpringHill Suites by Marriott Florence
A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.
A modern office space with multiple workstations, ergonomic chairs, and pendant lighting.
A hotel room with a sofa, a dining table, a coffee maker, a TV, and artwork on the wall.
A modern kitchen with a central island, built-in appliances, and a stone backsplash.

12. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
Florence
United States
Tishia
$131 nightly
$147 total
Nov 15 - Nov 16
Total with taxes and fees
Staybridge Suites Florence - Civic Center by IHG
A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.
A snack and beverage display area with shelves stocked with various brands and a refrigerator with beverages.
A coffee station with two coffee machines and a display of coffee pods and cups.
An outdoor patio area with lounge chairs and tables, a brick building, and a clear sky.

13. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Florence
United States
Leigh
$114 nightly
$128 total
Oct 25 - Oct 26
Total with taxes and fees
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A building with two red doors, one labeled 'Office' and the other '101'. There is a welcome sign and a mailbox on the wall.
A house with a stone-paved entrance, a bench, and two red doors labeled "OFFICE" and "PRIVATE."
A room with a sofa, a small table, a chair, a lamp, and a door.
A compact living space with a dining area, kitchenette, and seating area.

14. Affordable Suites Florence

Affordable Suites Florence
Florence
United States
Cheyenne
$86 nightly
$97 total
Nov 19 - Nov 20
Total with taxes and fees
Affordable Suites Florence
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.
A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.
A self-service beverage station with refrigerated and non-refrigerated drink options, snack shelves, and a sign indicating the location.
A modern hotel room with a kitchenette, a grey sofa, a dining area, and a sign that reads "A Great Day Starts With Breakfast."

15. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
Florence
United States
Crystal
$110 nightly
$123 total
Nov 1 - Nov 2
Total with taxes and fees
TownePlace Suites by Marriott Florence
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.
A modern hotel with a prominent 'TRU by Hilton' sign, a well-lit entrance, and a landscaped front yard.
A modern lounge area with seating, tables, and a pool table.
A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.

16. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
Florence
United States
Margarita
$115 nightly
$129 total
Oct 27 - Oct 28
Total with taxes and fees
Tru by Hilton Florence I-95
A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.
A hotel room with a bed, sofa, TV, and a desk.
A modern breakfast area with a buffet setup, including a microwave, coffee maker, and various food items.
A La Quinta Inn & Suites hotel with a modern facade, a well-lit entrance, and a landscaped garden area.

17. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
Florence
United States
LaShanda
$86 nightly
$96 total
Oct 25 - Oct 26
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Florence
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
A hotel room with two beds, a desk, a TV, and a window with patterned curtains.
A hotel lobby with a reception desk, seating area, and a welcome mat.
A lobby with a fireplace, seating area, and a television.

18. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
Florence
United States
William
$114 nightly
$128 total
Nov 1 - Nov 2
Total with taxes and fees
Hampton Inn & Suites Florence Center
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.
A lobby with leather sofas, a coffee table, potted plants, and a reception desk.
A Hampton Inn & Suites hotel with a well-lit entrance, multiple floors, and a parking area.
A corridor with shelves stocked with snacks and a frozen food display.

19. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
Florence
United States
Ladavish
$122 nightly
$137 total
Oct 27 - Oct 28
Total with taxes and fees
Hampton Inn & Suites Florence-North-I-95
A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.
A large, two-story building with a central entrance flanked by columns, labeled "DIR FRANK B. LEE NURSING BUILDING."
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.
A hotel lobby with a reception desk, a seating area with green sofas, and a dining area with tables and chairs.

20. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
Florence
United States
Christopher
$131 nightly
$147 total
Oct 25 - Oct 26
Total with taxes and fees
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
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Top Effingham Hotel Reviews

The Inn at the Crossroads

The Inn at the Crossroads

10/10 Excellent
"they were very helpful and friendly."
Jamie 3-night trip
Posted 13 hours ago
The Inn at the Crossroads
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

10/10 Excellent
"The staff was amazing, went over and beyond the call of customer service. Everything was reasonably priced especially with all that is offered with the hotel and the surrounding area."
Katie 1-night trip
Posted 18 hours ago
Hyatt Place Florence Downtown
Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

8/10 Good
"very attentive staff"
Daniel 1-night trip
Posted 1 day ago
Hampton Inn & Suites Florence Center
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

10/10 Excellent
"Hotel was good, the breakfast was great, with a huge selection. Price was very good. The rooms were nice, too."
David and Farah 1-night trip
Posted 1 day ago
Howard Johnson by Wyndham Florence
Best Western Executive Inn

Best Western Executive Inn

10/10 Excellent
"Overnight stay while solo traveling. Clean, safe and friendly. Breakfast was the usual. Not bad but not great. For the price this was a great choice."
Lisa 1-night trip
Posted 6 days ago
Best Western Executive Inn

More cheap stays in Effingham

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC
$65 nightly
$72 total
Oct 22 - Oct 23
Total with taxes and fees
8.6/10 Excellent! (2,746 reviews)
Howard Johnson by Wyndham Florence
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

140 Dunbarton Dr Florence SC
$69 nightly
$77 total
Oct 22 - Oct 23
Total with taxes and fees
Days Inn by Wyndham Florence Near Civic Center
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

150 Dunbarton Dr Florence SC
$89 nightly
$100 total
Oct 27 - Oct 28
Total with taxes and fees
Quality Inn & Suites Florence Civic Center
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

1729 Mandeville Road Florence SC
$90 nightly
$101 total
Oct 25 - Oct 26
Total with taxes and fees
Park Inn by Radisson Florence, SC
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

527 Woody Jones Blvd Florence SC
$101 nightly
$113 total
Nov 10 - Nov 11
Total with taxes and fees
Comfort Inn & Suites Florence Center Area
The Inn at the Crossroads

The Inn at the Crossroads

128 West Main Street Lake City SC
$126 nightly
$142 total
Nov 19 - Nov 20
Total with taxes and fees
9.4/10 Exceptional! (1,003 reviews)
The Inn at the Crossroads

Hotels in Effingham with star-rating

Frequently asked questions

What is the best area to stay in Effingham?
The best area to stay in Effingham is near the intersection of US-301 and I-95, as this offers the most convenient access to amenities and onward travel.This area is primarily characterized by its array of hotels, restaurants, and gas stations, strategically located for travelers passing through or needing a stopover. You'll find most services concentrated along US-301, just off the I-95 exits. While not a tourist destination in itself, it provides all the necessary conveniences for a comfortable stay.For solo travelers or couples on a road trip, this location is ideal. It offers quick access to the interstate, making it easy to continue your journey. The concentration of dining options, from casual eateries to sit-down restaurants, provides variety without requiring extensive travel.
When is the best time to go to Effingham?
The best time to visit Effingham, South Carolina, is during the spring (March to May) and fall (September to November) months.These seasons offer pleasant weather with mild temperatures, ideal for enjoying outdoor activities without the intense heat and humidity of summer or the cooler, sometimes unpredictable, temperatures of winter. Spring brings blooming flora, while fall showcases colorful foliage, making for scenic drives and comfortable exploration of the local area.For travelers who prefer warm weather and don't mind higher humidity, the summer months (June to August) are also an option. During this time, the days are long, allowing for extended outdoor enjoyment, though afternoon thunderstorms can occur.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Effingham.
How much is the nightly rate at a Effingham hotel?
Prices for hotels in Effingham often vary, but you can find a great deal from $72 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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