Find hotels in Effingham, SC from $63

  • Upfront pricing

    Our total price for your stay includes taxes and fees
  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Effingham hotels

Quality Inn Mullins - Marion

Quality Inn Mullins - Marion
2.5 star property
Marion
7.8 out of 10, Good, (391 reviews)
"It was ok clean would stay there again. "
United States
jeff
$98 nightly
The price is $107
Mar 27 - Mar 28
Total with taxes and fees
Quality Inn Mullins - Marion

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.4 out of 10, Very Good, (1,011 reviews)
"The stay was great"
United States
Dianne
$131 nightly
The price is $147
Mar 29 - Mar 30
Total with taxes and fees
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Best Western Executive Inn

Best Western Executive Inn
2.5 star property
Latta
8.2 out of 10, Very Good, (964 reviews)
"Would definitely stay again !!!"
United States
Tracy
$104 nightly
The price is $114
Apr 7 - Apr 8
Total with taxes and fees
Best Western Executive Inn

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2,573 reviews)
"Can’t beat the price for a clean room, comfy bed and complementary breakfast items. "
United States
Mary
$67 nightly
The price is $75
Mar 15 - Mar 16
Total with taxes and fees
Howard Johnson by Wyndham Florence

Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center
2.5 star property
Florence
7.0 out of 10, Good, (1,002 reviews)
"Everything was great. I slept very well. Bed and linen were clean. Staff was friendly"
United States
Elvira
$60 nightly
The price is $68
Apr 7 - Apr 8
Total with taxes and fees
Days Inn by Wyndham Florence Near Civic Center

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2,226 reviews)
"Staff was helpful and the room/bathroom were very nice."
United States
Diane
$86 nightly
The price is $96
Mar 29 - Mar 30
Total with taxes and fees
Park Inn by Radisson Florence, SC

Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
3.0 star property
Florence
9.2 out of 10, Wonderful, (595 reviews)
"Great place to stay while we have long trip from FL to NY"
United States
Sergii
$110 nightly
The price is $123
Mar 29 - Mar 30
Total with taxes and fees
Fairfield Inn & Suites by Marriott Florence I-20

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (873 reviews)
"Busy hotel. Nice rooms awesome free breakfast "
United States
Ken
$110 nightly
The price is $123
Apr 5 - Apr 6
Total with taxes and fees
Hampton Inn & Suites Florence-North-I-95

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.2 out of 10, Wonderful, (1,222 reviews)
"Clean room, good breakfast...very nice overnight stay."
United States
Gerry
$101 nightly
The price is $113
Mar 29 - Mar 30
Total with taxes and fees
Comfort Inn & Suites Florence Center Area

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
9.0 out of 10, Wonderful, (1,001 reviews)
"It was a beautiful room and breakfast was great. Staff was wonderful "
United States
Stephanie
$122 nightly
The price is $137
Mar 30 - Mar 31
Total with taxes and fees
Hyatt Place Florence Downtown

Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence
2.0 star property
Florence
6.8 out of 10, (1,001 reviews)
"Friendly staff, clean room, very comfortable bed "
United States
Willie
$61 nightly
The price is $68
Mar 15 - Mar 16
Total with taxes and fees
Microtel Inn & Suites by Wyndham Florence

Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG
2.5 star property
Latta
9.4 out of 10, Exceptional, (563 reviews)
"I only visited for a quick over night stay. But the hotel was clean and inviting. It was easy to check in and the bed was very comfortable. "
United States
Randolph
$122 nightly
The price is $133
Apr 6 - Apr 7
Total with taxes and fees
Holiday Inn Express & Suites Latta by IHG

Super 8 by Wyndham Florence

Super 8 by Wyndham Florence
2.0 star property
Florence
7.0 out of 10, Good, (1,004 reviews)
"Perfect overnight spot"
United States
Martin
$58 nightly
The price is $65
Mar 23 - Mar 24
Total with taxes and fees
Super 8 by Wyndham Florence

Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
Florence
8.4 out of 10, Very Good, (1,000 reviews)
"Great accommodations and courteous staff"
United States
Leslie
$107 nightly
The price is $119
Mar 29 - Mar 30
Total with taxes and fees
Comfort Suites Florence I-95

Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North
2.0 star property
Florence
6.8 out of 10, (1,001 reviews)
"Great room and reasonable price "
United States
Hattab
$62 nightly
The price is $70
Mar 15 - Mar 16
Total with taxes and fees
Days Inn by Wyndham Florence/I-95 North

Florence Inn and Suites

Florence Inn and Suites
2.5 star property
Florence
6.4 out of 10, (335 reviews)
"Easy close secure"
United States
Kathryn
$55 nightly
The price is $62
Apr 12 - Apr 13
Total with taxes and fees
Florence Inn and Suites

Budget Inn Timmonsville

Budget Inn Timmonsville
2.0 star property
Timmonsville
7.0 out of 10, Good, (329 reviews)
"Very nice, always clean and easy on off access from route 95."
United States
Debbie
$61 nightly
The price is $68
Mar 15 - Mar 16
Total with taxes and fees
Budget Inn Timmonsville

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
8.0 out of 10, Very Good, (1,645 reviews)
"Clean rooms, friendly staff, great breakfast "
United States
Donna
$103 nightly
The price is $115
Mar 15 - Mar 16
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Florence

TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
Florence
9.0 out of 10, Wonderful, (775 reviews)
"Clean room excellent staff good breakfast "
United States
Brian
$114 nightly
The price is $128
Mar 15 - Mar 16
Total with taxes and fees
TownePlace Suites by Marriott Florence

Best Western Inn

Best Western Inn
2.5 star property
Florence
7.8 out of 10, Good, (1,000 reviews)
"Very friendly staff. The room was very spacious. "
United States
Arika
$99 nightly
The price is $111
Mar 15 - Mar 16
Total with taxes and fees
Best Western Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.
Save an average of 15% on thousands of hotels when you're signed in

Top Effingham Hotel Reviews

More cheap stays in Effingham

Hotels in Effingham with star-rating

Frequently asked questions

What is the best area to stay in Effingham?
The best area to stay in Effingham is near the intersection of US-301 and I-95, as this offers the most convenient access to amenities and onward travel.

This area is primarily characterized by its array of hotels, restaurants, and gas stations, strategically located for travelers passing through or needing a stopover. You'll find most services concentrated along US-301, just off the I-95 exits. While not a tourist destination in itself, it provides all the necessary conveniences for a comfortable stay.

For solo travelers or couples on a road trip, this location is ideal. It offers quick access to the interstate, making it easy to continue your journey. The concentration of dining options, from casual eateries to sit-down restaurants, provides variety without requiring extensive travel.
When is the best time to go to Effingham?
The best time to visit Effingham, South Carolina, is during the spring (March to May) and fall (September to November) months.

These seasons offer pleasant weather with mild temperatures, ideal for enjoying outdoor activities without the intense heat and humidity of summer or the cooler, sometimes unpredictable, temperatures of winter. Spring brings blooming flora, while fall showcases colorful foliage, making for scenic drives and comfortable exploration of the local area.

For travelers who prefer warm weather and don't mind higher humidity, the summer months (June to August) are also an option. During this time, the days are long, allowing for extended outdoor enjoyment, though afternoon thunderstorms can occur.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Effingham.
How can I save on a Effingham hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Effingham hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Effingham hotel?
Prices for hotels in Effingham often vary, but you can find a great deal from $63 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia